Releases: Open-Systems-Pharmacology/PK-Sim
Releases · Open-Systems-Pharmacology/PK-Sim
Version 11.3.208
Version 11.3.208, released with the OSP Suite 11 Update 3
Downloads
- PK-Sim Portable version
MD5-Hash SHA256-Hash b35a7e90b09a08bd8cd0ce259b7e250b60d2b51a93892665e472707aea10a24a27c353d3de3bfb753663bf6daed6a766 - PK-Sim Installer
MD5-Hash SHA256-Hash dcdf515e7f83c947f34365dce1eea0dc2e594dabb5000c03dc7613a4a60c61525507cb9bb95ad47062b516bd7a2182cb
What's Changed
- Observed data mappings get duplicated when cloning a simulation
- Changing the transport direction in the expression profile is not applied in the simulation.
- Projects created with version
$\leq 10$ are sometimes not exported correctly to a snapshot with version$\geq 11$ . - Error displaying PK analysis in population simulation in some scenarios
- Create Individual: wrongly memorized age
- Unit of t1/2 in individual enzyme expression not updated when changing unit in expression profile
Concentrationparameter must be created withCanBeVaried = false
Version 11.2.142
Version 11.2.142, released with the OSP Suite 11 Update 2
Downloads
- PK-Sim Portable version
MD5-Hash SHA256-Hash d82801ad16fe7f29b09672cb9c90b676049edf8ec97a3990fd313467756d14fc8db1ea0a287dab88a68dd1520da6f695 - PK-Sim Installer
MD5-Hash SHA256-Hash 17b1be42056f453b4280fc689d57ed0b69b9563f0d18bbcb528fc330f75f7575161704e77311c4fae7dc3ef5c08446c0
What's Changed
- Fixes #2553 pksim changes molecule name by @msevestre in #2561
- Fixes #2536 loading project from snapshot observed data by @msevestre in #2560
- Fixes #2558 project created with v10< do not export properly by @msevestre in #2559
- Fixes #2563 notification weird column no image data by @msevestre in #2564
- Fixes #1488 number of cells missing by @msevestre in #2579
- Small change to make test pass again by @msevestre in #2582
- updating to latest core by @georgeDaskalakis in #2588
- Version 11.2 by @Yuri05 in #2607
Full Changelog: v11.1.137...v11.2.142
Contributors
msevestre, Yuri05, and georgeDaskalakis
Assets 4
Version 11.1.137
Version 11.1.137, released with the OSP Suite 11 Update 1
Downloads
- PK-Sim Portable version
(MD5-Hash:317a908550c63e572044c27daa623dee; SHA256-Hash:50e0b1381d65672ffaec88c360afc2e4e6f3e05cfc7cf00e1fd4d5612e76933f) - PK-Sim Installer
(MD5-Hash:6677078cc77663f5ebe30f05cff6efcb; SHA256-Hash:79c647b83df642bcae4b442772adde7b569cb9436308db738f383390c2a8b9b9)
What's Changed
- 2253 initial concentration error by @msevestre in #2257
- include pk properties for population simulations by @abdelr in #2227
- Fixes #2249 scale button by @msevestre in #2269
- Fixes #2256 snapshot initial concentration issue by @msevestre in #2267
- Fixes #2241 initial concentration value by @msevestre in #2268
- Fixes #2251 also load metabolites by @msevestre in #2266
- Fixes #2135 rename column "rate"=>"formula_rate" by @Yuri05 in #2280
- Fixes #2281 PK-Sim DB: unused tables by @Yuri05 in #2288
- 2248 empty sapces by @msevestre in #2294
- Fixes #2287 create sim by @msevestre in #2295
- Fixes #2274 UI axes by @msevestre in #2296
- Fixes #2289, Fixes #2273, Fixes #2263 by @msevestre in #2297
- Fixes #2276 expression profile by @msevestre in #2298
- Update to latest core by @msevestre in #2307
- Fixes #2318 tab empty by @msevestre in #2319
- Fixes #2270 remove reset button by @msevestre in #2320
- Update dll to latest by @msevestre in #2326
- Fixes #2254 refresh problem by @msevestre in #2321
- Fixes #2302 bug influx by @msevestre in #2327
- Fixes #2322 pk parameters tab empty by @msevestre in #2332
- 2328 db by @Yuri05 in #2333
- Fixes #2331 Rename tabs for pk analysis on population simulations by @rwmcintosh in #2337
- Fixes #2324 PopSim: PK parameters not shown for all compounds by @rwmcintosh in #2340
- 2323 Popsim pk parameters not shown correctly for ranges by @rwmcintosh in #2343
- Fixes #2323 Popsim PkParameters not shown correctly for all ranges by @rwmcintosh in #2346
- Fixes #2338 Aggregate population PK values with median instead of ari… by @rwmcintosh in #2350
- Fixes update core by @rwmcintosh in #2349
- Fixes #2316 bb markdown difference by @msevestre in #2352
- update core to 11.1.22 by @rwmcintosh in #2355
- Fixes #2356 Update to SimModel 4.0.0.52 causes a PK-Sim test to fail by @Yuri05 in #2357
- Fixes #2260 - including "Global" PK-Parameters into the box-plot/scatter plot by @rwmcintosh in #2359
- Plugin new Simulation OutputMapings and Charts by @georgeDaskalakis in #2361
- Plugging in IWithHasChanged by @georgeDaskalakis in #2362
- Update dimensions, dlls, templates, pk parameters by @msevestre in #2375
- 2358 calculation of global pk parameters by @rwmcintosh in #2369
- Fixes #2377 Reword global PK Analysis description by @rwmcintosh in #2378
- Fixes #2409 Error when adding Bioavailability by @rwmcintosh in #2412
- Fixes #2410 some calculation in global pk wrong by @rwmcintosh in #2413
- Fixes #2405 disappear with clone by @msevestre in #2415
- Fixes #2402 Observed data tab in a simulation not refreshed if previo… by @rwmcintosh in #2418
- Fixes #2403 observed data mapping not saved in snapshot. Also Fixes #… by @msevestre in #2423
- Fixes #2424 output mapping serialization by @msevestre in #2425
- Fixes #2401 plots lost during clone by @msevestre in #2428
- Fixes #2424 output mapping serializatin extra by @msevestre in #2426
- 2419 inconsistencies in comparison chart by @georgeDaskalakis in #2431
- Fixes #2430 order of tab by @msevestre in #2432
- update core to latest by @rwmcintosh in #2433
- Make PKSim compile again by @msevestre in #2435
- Fixes CKD not experimental by @msevestre in #2441
- 2438 outptu mappings not cleared by @georgeDaskalakis in #2444
- Fixes #2439 Misleading info in global POP PK Analysis if no parameter… by @rwmcintosh in #2459
- Fixes #2469 show hidden entities by @msevestre in #2488
- Fixes buil failing by @msevestre in #2489
- Fixes #2495 failing tests by @msevestre in #2499
- Fixes #2485 observed added mobi by @msevestre in #2500
- Fixes #2484 bug when exporting pop simulation by @msevestre in #2503
- Fixes #2275 #2279 #2277 by updating OSPSuite.Core by @rwmcintosh in #2506
- Fixes #2405 mapping lost after configure by @msevestre in #2507
- Fixes #2255 resetting concentration issue by @msevestre in #2512
- update core by @rwmcintosh in #2514
- Prepare for v11_1 by @msevestre in #2515
- Fixes #2516 Cannot run population simulations imported from pkml by @rwmcintosh in #2517
- Fixes #2518 11.1 Cannot show PK-Analysis in a population simulations … by @rwmcintosh in #2520
- Updated OSPSuite.Core and OSPSuite.BuildingBlockTemplates by @Yuri05 in #2524
- Version 11.1 by @msevestre in #2527
Full Changelog: v11.0.150...v11.1.137
Contributors
rwmcintosh, msevestre, and 3 other contributors
Assets 4
Version 11.0.150
Version 11.0.150 delivered with the OSP Suite 11.
Downloads
- PK-Sim Portable version
(MD5-Hash:1008f9e7ad3fdc7d38a7c01167606879; SHA256-Hash:a58fe45b3ccb46fd75a80090cb8197a56ae18d595507add634e9582abdc11366) - PK-Sim Installer
(MD5-Hash:51f71a6e7b2eca2b6acfdb38d38c6cf8; SHA256-Hash:9cfaa927f3e91f84d90b801ede746eab8ca339c2c97bc9cfc12945ad99b1ad76)
What's Changed
- Fixes #1904 and Fixes #1905 by @msevestre in #1907
- 1930 lumen mucosa transporter by @msevestre in #1940
- Fixes #1860 Predefined templates using main file defined in github by @msevestre in #1891
- Fixes #1929 hill transporter issue by @msevestre in #1941
- Fixes #1912 initial conc variable pop by @msevestre in #1937
- Fixes update core exp profile by @msevestre in #1942
- Added Cat as copy of Beagle; added Cattle as copy of Minipig; no species-specific values set yet by @Yuri05 in #1956
- Cat cattle 2 by @Yuri05 in #1960
- Fixes #1977 Cat and Cattle: small fixes by @Yuri05 in #1978
- Fixes #1983 Cat Integration. Integration tests failing by @Yuri05 in #1985
- Fixes #1984 brain transporter by @msevestre in #1992
- Expression profile feature by @msevestre in #1949
- Update devexpress by @msevestre in #1999
- Investigate differences batch by @msevestre in #2002
- 2041 remove example project by @msevestre in #2045
- 2041 remove example project by @msevestre in #2046
- Fixes #834 multi select delete by @msevestre in #2044
- Fixes #1939 template db auto update by @msevestre in #2043
- Ckd population feature by @msevestre in #2008
- Work on #2042 remove duplicates by @msevestre in #2048
- Fixes #2041 by @msevestre in #2054
- Fixes #2052 renaming uses the wrong type by @msevestre in #2056
- Get a graph again by @msevestre in #2057
- 2039 red blood cells by @msevestre in #2058
- Fixes #1933 Add urine compartment by @msevestre in #2049
- Change default value in code by @msevestre in #2060
- 2061 importer dimensions by @georgeDaskalakis in #2062
- Control size issue by @msevestre in #2064
- Fixes #2065 cannot load project by @msevestre in #2066
- Fixes #2068 hide disease state by @msevestre in #2076
- 2073 molweight correction by @georgeDaskalakis in #2077
- Fixes #1522 symbol does not match by @msevestre in #2067
- Fixes #2081 PKSim CLI filter simulation by @msevestre in #2082
- updating pk-sim by @georgeDaskalakis in #2079
- Fixes #2084 problem with expression profile by @msevestre in #2085
- WIP #2071 ux issue by @msevestre in #2080
- Multiple PI in parallel by @abdelr in #2047
- updating nugets by @georgeDaskalakis in #2091
- return null if subject not implementing IWithId by @abdelr in #2094
- Fixes #1755 aucr cmax r not calculated properly by @msevestre in #2093
- 2055 old values not scaled by @msevestre in #2092
- Perf oroptimization: Create / Edit Simulation by @msevestre in #2097
- FIxes #2099 export all when empty by @msevestre in #2100
- Fixes #2059 add explanation phenotype by @msevestre in #2101
- 2059 add explanation phenotypoe by @msevestre in #2108
- Fixes #2105 qualified status by @msevestre in #2109
- Fixes #2025 remove pdf export by @msevestre in #2110
- 2112 fraction expressed should be formula by @msevestre in #2115
- 2113 property molecule psv by @msevestre in #2117
- Layout issue by @msevestre in #2119
- Update for new modal by @msevestre in #2120
- Fixes #2123 rename target eGFR by @msevestre in #2124
- Fixes #2127 snapshot simulation count by @msevestre in #2128
- Layout issue by @msevestre in #2130
- Fixes #2118 sum formula for volume plasma by @msevestre in #2131
- Fixes update svg support by @msevestre in #2137
- 2138 plot title and description not copied by @msevestre in #2139
- Fixes #2140 fraction basolateral not set properly by @msevestre in #2144
- Fixes #2142 remove unused observers by @msevestre in #2145
- Fixes #2143 missing icons by @msevestre in #2146
- Fixes #2133 liver zonation wrong formula by @msevestre in #2150
- Fixes #2034 info missing by @msevestre in #2147
- Fixes #2151 ontogeny like by @msevestre in #2152
- Fixes #2154 scale wrong size by @msevestre in #2156
- 2153 template issue by @msevestre in #2155
- Fixes #2158 add check box disable run by @msevestre in #2159
- Fixes #2160 population snapshot disease state by @msevestre in #2161
- Fixes #2162 export settings always by @msevestre in #2163
- 2170 some issue with fraciton expressed by @msevestre in #2171
- Fixes #2169 demographic order and Fixes #2164 listing by @msevestre in #2172
- 2166 adding expression profile filter existing by @msevestre in #2173
- 2132 better formulas by @msevestre in #2157
- Fixes #2121 default values by @msevestre in #2174
- Fixes #2175 renaming expression profile by @msevestre in #2177
- Fixes #2176 rename pgp to deprecated by @msevestre in #2178
- 2181 project conversion issue by @msevestre in #2182
- Fixes #2179 pgp error by @msevestre in #2180
- Color grouping od feature by @georgeDaskalakis in #2148
- Fixes #2183 wrong error range by @msevestre in #2184
- Fixes #2188 jacobian option by @msevestre in #2189
- 2190 project conversion issue by @msevestre in #2191
- Fixes #2192 revert change in kidney clearance by @msevestre in https://github.com/O...
Contributors
msevestre, abdelr, and 2 other contributors
Assets 4
Version 10.0.257
Version 10.0.257 delivered with the OSP Suite 10.
Downloads
- PK-Sim Portable version
(MD5-Hash:9b399ca80923d6df5f76522dc3964182; SHA256-Hash:63c9f384bed7056dd2fca8f8c9189f40c97d53ce00cf11e1a53643438d2b4a73) - PK-Sim Installer
(MD5-Hash:9dcc7f7ae093031057b5c539ae30efbf; SHA256-Hash:35514ae17f7fc7db07c655e52dc1cc19ad7d08d12a24f9fc5bff263db1f3ed1a)
Version 9.1
Hotfix/v9.1
Downloads
- PK-Sim Portable version
(MD5-Hash:a2dccf0c0cb225b04ae1843b3efb514f; SHA256-Hash:1470f95a4aef6d767fa20fdd420fff888ef28869b2b840e949994fb5143eb41f) - PK-Sim Installer
(MD5-Hash:8b4499a3e7725b0eb3d9e6f7634047e1; SHA256-Hash:efd628260fcea154c1cd3992a51f663c82a460bfc4f21018224f616046e0cfe7)
Version 9.0
Version 9.0 delivered with OSP Suite Version 9
Downloads
- PK-Sim Portable version
(MD5-Hash:4d4e78fa25900bee3d46fe2f821192b4; SHA256-Hash:6d6664d6e9e38990fba2c28d340b25d10edeebe4726149a26b0dbe8910922d59) - PK-Sim Installer
(MD5-Hash:16d60b16a3ab6d0081a6325a0e688d00; SHA256-Hash:9333bbef20d64a0fd43e98694decce3320d2ebab5eaa59be1cd141077a8a4368)
Version 8.0
Version 8.0 delivered with OSP Suite Version 8
Downloads
- PK-Sim Portable version
(MD5-Hash:73ed849a2b1973ed65f7dae8da4cd732; SHA256-Hash:ed7c4b749aaf61abb8107dadee8c62eb05477f138e0504f1b9011ea56dc281d7) - PK-Sim Installer
(MD5-Hash:0678dd4bc25883bfc77693e76553c1b1; SHA256-Hash:10119a4507a3bdc813e53b03a03c3ff84dea77e426f2983a8534dd9bea7d04ed)
Version 7.4.0
Version 7.4.0 released with Open Systems Pharmacology Suite Version 7.4.0
Downloads
- PK-Sim Portable version
(MD5-Hash:150019b16073dbf2c6d9b30151442f5a; SHA256-Hash:a537434cc8e5ed710c524e5148ef413ee8232e34dd2e85f1e0fd23dbc69b1b3b) - PK-Sim Installer
(MD5-Hash:d9883deed5c87b543dce390e37370f61; SHA256-Hash:450ee530f30e59d1e9bb57d7c9d9144f4b826f0d285e2199d8f94212951af9b5)
Version 7.3.0
Version 7.3.0 released with Open Systems Pharmacology Suite Version 7.3.0
Downloads
- PK-Sim Portable version
(MD5-Hash:58e1902357570c6e6f4d9ca8861ecbc4; SHA256-Hash:afac0886ace395c389235a5888bb54eddbf45158ca448b31015a5174e8bc3fd3) - PK-Sim Installer
(MD5-Hash:9f709be7f1a3fcefdf653768bab3e1bb; SHA256-Hash:7163ad871aed6f457b80dc8d686824760166264e533442b0821298c63f87e423)