Comprehensive design of CRISPR gRNAs for nucleases and base editors

On-Target and Off-Target Scoring Algorithms for CRISPR gRNAs

A gRNA database generation tool.

Collection of R packages that work in harmony for CRISPR gRNA design

CRISPR, faster, better – The Crackling method for whole-genome target detection

Tutorials for the crisprVerse

A guideRNA design tool for the modern era.

CRISPR Guide RNA Designer

Base functions and classes for CRISPR gRNA design

Useful human and mouse data for the crisprVerse ecosystem

Visualization of CRISPR guide RNAs (gRNAs)

Bowtie-based alignment of CRISPR gRNA spacer sequences

A Snakemake workflow for the design of small guide RNAs (sgRNAs) for CRISPR applications.

Shiny interface for CRISPR gRNAs designed with the crisprVerse

Pre-trained models for the crisprScore package

BWA-based alignment of CRISPR gRNA spacer sequences

Creates a construct developed by the Niles Lab at MIT, designed to deliver a 3' UTR post-transcriptional regulatory element payload to a specific given gene in Plasmodium falciparum.

ALLEGRO: An Algorithm Leveraging Linear Programing to Enhance Guide RNA Optimization

Fork of Azimuth (Machine Learning-Based Predictive Modelling of CRISPR/Cas9 guide efficiency), updated to work with Python 3.10+

⛓️ Automating construction of oligo library sequences for oligo array synthesis.