Fantasista.DNA

A library for reading, handling and working with bioinformatic files and formats.
The library is work in progress, and it is mainly created to be able to work with this stuff myself.

Roadmap

The first versions will prioritize reading different kinds of file formats. See list below over supported files.

Next versions:

• Reading Cram files
• Reading Bam files

Install

$ dotnet add package Fantasista.DNA

Documentation

Examples
Complete API Documentation

Supported file formats:

File format	Class	Description
Variant Call Format (VCF)	VcfStreamReader	Reads variations between reference genomes and sequences aligned to it
FASTA	FastaStreamReader	Reads the sequence format FASTA
FASTQ	FastqStreamReader	Reads the sequence format FASTQ
SAM	SamStreamReader	Reads SAM Files
Gff3	Gff3StreamReader	Reads Gff3 Files

Other supported parses

Type	Class	Description
HGVS	HgvsVariant	Human Genome Variation Society Formatting iternationally-recognized standard for the description of DNA, RNA, and protein sequence variants.

I found a bug

Please use Github Issues, or even better, send a pull request.

Where to find data

Are you new to bioinformatics?
There are a lot of places to find data files you could use for starting in bioinformatics.

• The ftp server at ClinVar
• Uniprot have a Download page