If your scRNA-seq data have two conditions, e.g., disease and control, and you'd like to know which cells changed the most in the disease condition, then Emergene is the tool for you. Similarly, if you are studying development, and want to understand the emergence of cell type diversity, Emergene can help you with that. Not only scRNA-seq data, but also the spatial transcriptomics data could be used as the input for Emergene.
We are now preparing detailed tutorials and lauching a website for Emergene. Thank you for your interest in our tool!
If Emergene is useful for your research, please consider citing Wu et al., Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes, bioRxiv (2024).
Min Dai Email: dai@broadinstitute.org, Fishell Lab