UpSet ReadMe

Created: August 11, 2022 Created by: Anonymous Tags: Andersen Lab, CeNGEN Project, R

Overview

This code allows for the generation of UpSet plots to visualize data from the CeNGEN database.

Required Packages:

• R/ComplexUpset
• R/Tidyverse

Data Acquisition

Expression data for various genes by neuronal cell subtype can be downloaded directly from CeNGEN.

Neurotransmitter classification of each neuronal cell subtype was adapted from the Neurotransmitters Table on WormAtlas.

• These data were adapted to be compatible with CeNGEN data. Edits were made to include the novel neuronal cell subtypes as described by Taylor et al. 2021. The adapted data table is available within this repository in the “data” folder, titled “ModifiedforCeNGEN-Ce_NTtables_Loer&Rand2022.csv”

Example Code

Example code is available comparing the expression of four genes: avr-14, avr-15, glc-1, and ben-1.

• The data downloaded from CeNGEN for this example are available within this repository in the “data” folder.