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RSANet: Recurrent Slice-wise Attention Network for Multiple Sclerosis Lesion Segmentation (MICCAI 2019)

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Pytorch

Hang Zhang, Jinwei Zhang, Qihao Zhang, Jeremy Kim, Shun Zhang, Susan A. Gauthier, Pascal Spincemaille, Thanh D. Nguyen, Mert R. Sabuncu, and Yi Wang.

Background

In this paper, we propose a novel recurrent slice-wise attention network (RSANet), which models 3D MRI images as sequences of slices and captures long-range dependencies through a recurrent manner to utilize global contextual information of MS lesions. Three major advantages of RSANet are listed as follows:

  • Slice-wise attention (SA) block can help capture long-range dependencies among slices of any direction in 3D medical images;
  • By recurrently aggregating information from SA blocks along different directions can help capture global conetextual dependency information in 3D medical images;
  • Our recurrent mechanism makes the module GPU memory friendly and high computational efficient, which can be plugged into any existing 3D CNN structure with negligible cost.

Usage

The dataset used to verify the performance of the proposed method is unvailable per the policy of Weill Cornell Medicine. However, algorithms mentioned in the MICCAI'2019 paper are available in this repositorty.

We use a simple U-Net as backbone to show how our RSA block can be pugged into existing network.
./src/RSANet.py contains unet structure with detailed module import from ./src/backbones/unet.py. only three lines of code are needed to use RSA block from ./src/attModules/rsaModules.py, as can be read from ./src/RSANet.py.

Slice-wise Attention (SA) Block

SA block along one particular direction can be applied in your model based on your own needs.

Recurrent Slice-wise Attention (RSA) Block

RSA block can be considered as an approximation and regularization of non-local neural networks but with highly efficient memory and computation consumption.

An Example of Information Propagation in RSA Block

Qualitative Results

We choose one slice from a testing image, and compare the qualitative results of different models with ground truth labels. As we can see from the following figrues, since both 3D U-Net and non-local network are not able to efficiently capture the long-range dependencies between MS lesions and brain structure, they suffer from an over-segmenting problem.

From left to right are ground truth label, results of RSA-111, NCL-010 and 3D U-Net. (More details in the paper)

Citation

If you are inspired by RSANet or use our code, please cite:

@inproceedings{zhang2019rsanet,
  title = {RSANet: Recurrent Slice-Wise Attention Network for Multiple Sclerosis Lesion Segmentation},
  author = {Zhang, Hang and Zhang, Jinwei and Zhang, Qihao and Kim, Jeremy and Zhang, Shun and Gauthier, Susan A and Spincemaille, Pascal and Nguyen, Thanh D and Sabuncu, Mert and Wang, Yi},
  booktitle = {International Conference on Medical Image Computing and Computer-Assisted Intervention},
  pages = {411--419},
  year = {2019},
  organization = {Springer}
}