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mschatz committed Apr 7, 2017
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# GenomeScope: Fast genome analysis from unassembled short reads
## Vurture, GW, Sedlazeck, FJ, Nattestad, M, Underwood, CJ, Fang, H, Gurtowski, J, Schatz, MC (2017) *Bioinformatics* doi: https://doi.org/10.1093/bioinformatics/btx153

Current developments in de novo assembly technologies have been focused on relatively simple genomes. Even the human genome, with a heterozygosity rate of only ~0.1% and 2n diploid structure, is significantly simpler than many other species, especially plants. However, genomics is rapidly advancing towards sequencing more complex species such as pineapple, sugarcane, or wheat that have much higher rates of heterozygosity (>1% for pineapple), much higher ploidy (8n for sugarcane), and much larger genomes (16Gbp for wheat).

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