optopi

Modeling light inducible protein interaction systems via ODEs.

Getting Started

1. Install UV

$ curl -LsSf https://astral.sh/uv/install.sh | sh

2. Run Code

Fit model to ddFP data for LOVTRAP and iLID.

$ uv run fit_model

Simulate the response of the composite system RA-LOVfast + Zdk-iLIDslow + B3-sspBn to light stimulation.

$ uv run sim_model

Workflow

1. ddFP Biosensor Images

| RA-LOVfast + B3-Zdk |

Before Stimulation	After Stimulation

2. ODE Model Fit

LOVfast	LOVslow

LIDfast	LIDslow

3. Sparse Decoder Response Prediction

4. FM Response Prediction