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Merge pull request #229 from nextstrain/top-level-readme
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Add Quickstart section to the top level README
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joverlee521 authored Jan 20, 2024
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18 changes: 16 additions & 2 deletions README.md
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This repository contains three workflows for the analysis of mpox virus (MPXV) data:

- [`ingest/`](./ingest) - Download data from GenBank, clean and curate it and upload it to S3
- [`phylogenetic/`](./phylogenetic) - Make phylogenetic trees for nextstrain.org
- [`phylogenetic/`](./phylogenetic) - Filter sequences, align, construct phylogeny and export for visualization
- [`nextclade/`](./nextclade) - Make Nextclade datasets for nextstrain/nextclade_data

Each folder contains a README.md with more information.
Each folder contains a README.md with more information. The results of running both workflows are publicly visible at [nextstrain.org/mpox](https://nextstrain.org/mpox).

## Installation

Follow the [standard installation instructions](https://docs.nextstrain.org/en/latest/install.html) for Nextstrain's suite of software tools.

## Quickstart

Run the default phylogenetic workflow via:
```
cd phylogenetic/
nextstrain build .
nextstrain view .
```

## Documentation

- [Running a pathogen workflow](https://docs.nextstrain.org/en/latest/tutorials/running-a-workflow.html)
- [Contributor documentation](./CONTRIBUTING.md)
19 changes: 18 additions & 1 deletion phylogenetic/README.md
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## Software requirements

Follow the [standard installation instructions](https://docs.nextstrain.org/en/latest/install.html) for Nextstrain's suite of software tools.
Follow the [standard installation instructions](https://docs.nextstrain.org/en/latest/install.html)
for Nextstrain's suite of software tools.

## Usage

If you're unfamiliar with Nextstrain builds, you may want to follow our
[Running a Pathogen Workflow guide][] first and then come back here.

The easiest way to run this pathogen build is using the Nextstrain
command-line tool from within the `phylogenetic/` directory:

cd phylogenetic/
nextstrain build .

Once you've run the build, you can view the results with:

nextstrain view .

### Example build

You can run an example build using the example data provided in this repository via:
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* [sequences.fasta.xz](https://data.nextstrain.org/files/workflows/mpox/sequences.fasta.xz)
* [metadata.tsv.gz](https://data.nextstrain.org/files/workflows/mpox/metadata.tsv.gz)

The above datasets have been preprocessed and cleaned from GenBank using the
[ingest/](../ingest/) workflow and are updated at regular intervals.

Note that these data are generously shared by many labs around the world.
If you analyze and plan to publish using these data, please contact these labs first.

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