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lee-t committed Sep 19, 2024
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108 changes: 54 additions & 54 deletions DESCRIPTION
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Expand Up @@ -2,68 +2,68 @@ Package: AlphaMissenseR
Title: Accessing AlphaMissense Data Resources in R
Version: 1.1.5
Authors@R:
c(person(
"Martin", "Morgan", role = c("aut", "cre"),
email = "mtmorgan.xyz@gmail.com",
comment = c(ORCID = "0000-0002-5874-8148")
), person(
"Tram", "Nguyen",
role = "aut"
), person(
"Tyrone", "Lee",
role = "ctb"
), person(
"Nitesh", "Turaga",
role = "ctb"
), person(
"Chan Zuckerberg Initiative DAF CZF2019-002443",
role = "fnd"
), person(
"NIH NCI ITCR U24CA180996",
role = "fnd"
), person(
"NIH NCI IOTN U24CA232979",
role = "fnd"
), person(
"NIH NCI ARTNet U24CA274159",
role = "fnd"
))
c(person(
"Martin", "Morgan", role = c("aut", "cre"),
email = "mtmorgan.xyz@gmail.com",
comment = c(ORCID = "0000-0002-5874-8148")
), person(
"Tram", "Nguyen",
role = "aut"
), person(
"Tyrone", "Lee",
role = "ctb"
), person(
"Nitesh", "Turaga",
role = "ctb"
), person(
"Chan Zuckerberg Initiative DAF CZF2019-002443",
role = "fnd"
), person(
"NIH NCI ITCR U24CA180996",
role = "fnd"
), person(
"NIH NCI IOTN U24CA232979",
role = "fnd"
), person(
"NIH NCI ARTNet U24CA274159",
role = "fnd"
))
Description:
The AlphaMissense publication
<https://www.science.org/doi/epdf/10.1126/science.adg7492>
outlines how a variant of AlphaFold / DeepMind was used to predict
missense variant pathogenicity. Supporting data on Zenodo
<https://zenodo.org/record/10813168> include, for instance, 71M
variants across hg19 and hg38 genome builds. The 'AlphaMissenseR'
package allows ready access to the data, downloading individual
files to DuckDB databases for exploration and integration into *R*
and *Bioconductor* workflows.
The AlphaMissense publication
<https://www.science.org/doi/epdf/10.1126/science.adg7492>
outlines how a variant of AlphaFold / DeepMind was used to predict
missense variant pathogenicity. Supporting data on Zenodo
<https://zenodo.org/record/10813168> include, for instance, 71M
variants across hg19 and hg38 genome builds. The 'AlphaMissenseR'
package allows ready access to the data, downloading individual
files to DuckDB databases for exploration and integration into *R*
and *Bioconductor* workflows.
License: Artistic-2.0
URL: https://mtmorgan.github.io/AlphaMissenseR/
BugReports: https://github.com/mtmorgan/AlphaMissenseR/issues
Depends:
R (>= 4.3.0),
dplyr
R (>= 4.3.0),
dplyr
Imports:
rjsoncons (>= 1.0.1), DBI, duckdb (>= 0.9.1), rlang,
curl, BiocFileCache, spdl, memoise, BiocBaseUtils,
utils, stats, methods, whisker, ggplot2
rjsoncons (>= 1.0.1), DBI, duckdb (>= 0.9.1), rlang,
curl, BiocFileCache, spdl, memoise, BiocBaseUtils,
utils, stats, methods, whisker, ggplot2
Suggests:
BiocManager,
BiocGenerics,
GenomicRanges,
GenomeInfoDb,
AnnotationHub,
ensembldb,
httr,
tidyr,
r3dmol, bio3d, shiny, shiny.gosling,
colorspace,
knitr,
rmarkdown,
testthat (>= 3.0.0)
BiocManager,
BiocGenerics,
GenomicRanges,
GenomeInfoDb,
AnnotationHub,
ensembldb,
httr,
tidyr,
r3dmol, bio3d, shiny, shiny.gosling,
colorspace,
knitr,
rmarkdown,
testthat (>= 3.0.0)
biocViews: SNP, Annotation, FunctionalGenomics, StructuralPrediction,
Transcriptomics, VariantAnnotation, GenePrediction, ImmunoOncology
Transcriptomics, VariantAnnotation, GenePrediction, ImmunoOncology
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
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