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Merge pull request #18 from HannahVMeyer/dev
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Dev
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HannahVMeyer authored Sep 25, 2019
2 parents e8934e0 + e2a0fc8 commit a875b9f
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1 change: 1 addition & 0 deletions .Rbuildignore
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Expand Up @@ -15,3 +15,4 @@ inst/extdata/createData
inst/extdata/plink_log
pkgdown/
^cran-comments\.md$
pkgdown/
2 changes: 2 additions & 0 deletions NEWS.md
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Expand Up @@ -20,6 +20,8 @@
containing only related individuals; fixes #11
* Fix command for genotype conversion in 1000Genomes vignette, addressing issue
#10
* fix missing rownames error for overviewPerIndividualQC, when relatedness check
was included (issue #16, fc7a38b1f2b345d9c6c5d69f5dcf0bc57a857f62)


# plinkQC 0.2.2
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6 changes: 4 additions & 2 deletions docs/articles/plinkQC.html

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9 changes: 8 additions & 1 deletion vignettes/plinkQC.Rmd
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Expand Up @@ -115,6 +115,10 @@ individual IDs to the qcdir. These IDs will be removed in the computation of the
`perMarkerQC`. If the list is not present, `perMarkerQC` will send a message
about conducting the quality control on the entire dataset.

NB: To reduce the data size of the example data in `plinkQC`,
data.genome has already been reduced to the individuals that are related. Thus
the relatedness plots in C only show counts for related individuals only.

NB: To demonstrate the results of the ancestry check, the required eigenvector
file of the combined study and reference datasets have been precomputed and
for the purpose of this example will be copied to the `qcdir`. In practice,
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```{r load overviewIndividualQC, out.width = "500px", echo=FALSE}
par(mfrow=c(2,1), las=1)
knitr::include_graphics("overviewQC.png")
knitr::include_graphics("overviewAncestryQC.png")
```


Expand Down Expand Up @@ -273,6 +276,10 @@ complex family structures, the unrelated individuals per family are selected
(e.g. in a parents-offspring trio, the offspring will be marked as fail, while
the parents will be kept in the analysis).

NB: To reduce the data size of the example data in `plinkQC`,
data.genome has already been reduced to the individuals that are related. Thus
the relatedness plots in C only show counts for related individuals only.

```{r check related, eval=FALSE, fig.height=3, fig.width=5, fig.align='center'}
exclude_relatedness <- check_relatedness(indir=indir, qcdir=qcdir, name=name,
interactive=TRUE,
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