20.plot-compounds.ipynb

{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "# Visualize Tamai et al screen data"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {},
   "outputs": [],
   "source": [
    "import pandas\n",
    "\n",
    "import plotly.graph_objects as go\n",
    "import plotly.express as px"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {},
   "outputs": [
    {
     "data": {
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       "\n",
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       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>compound_name</th>\n",
       "      <th>compound_set</th>\n",
       "      <th>concentration</th>\n",
       "      <th>period_before</th>\n",
       "      <th>period_change</th>\n",
       "      <th>plate</th>\n",
       "      <th>notes</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td>Clindamycin·HCl</td>\n",
       "      <td>fda</td>\n",
       "      <td>1 uM</td>\n",
       "      <td>21.5</td>\n",
       "      <td>0.02917</td>\n",
       "      <td>1</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td>Felbamate</td>\n",
       "      <td>fda</td>\n",
       "      <td>1 uM</td>\n",
       "      <td>21.7</td>\n",
       "      <td>0.06250</td>\n",
       "      <td>1</td>\n",
       "      <td></td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
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      ],
      "text/plain": [
       "     compound_name compound_set concentration  period_before  period_change  \\\n",
       "0  Clindamycin·HCl          fda          1 uM           21.5        0.02917   \n",
       "1        Felbamate          fda          1 uM           21.7        0.06250   \n",
       "\n",
       "   plate notes  \n",
       "0      1        \n",
       "1      1        "
      ]
     },
     "execution_count": 2,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "screen_df = pandas.read_table(\"data/tamai-screen/combined-results.tsv\")\n",
    "screen_df.notes.fillna(\"\", inplace=True)\n",
    "screen_df.head(2)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {
    "scrolled": false
   },
   "outputs": [
    {
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       "        if (typeof require !== 'undefined') {\n",
       "        require.undef(\"plotly\");\n",
       "        requirejs.config({\n",
       "            paths: {\n",
       "                'plotly': ['https://cdn.plot.ly/plotly-latest.min']\n",
       "            }\n",
       "        });\n",
       "        require(['plotly'], function(Plotly) {\n",
       "            window._Plotly = Plotly;\n",
       "        });\n",
       "        }\n",
       "        </script>\n",
       "        "
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    },
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Mesylate\", \"Betaine \", \"Bethanechol Chloride\", \"Bimatoprost\", \"Esmolol\", \"Brompheniramine Maleate\", \"Budesonide\", \"Bupropion \", \"Busulfan\", \"Butorphanol-(+)-Tartrate (Schedule Iv)\", \"Capreomycin Sulfate\", \"Cefaclor\", \"Cefadroxil\", \"Cefazolin\\u00b7Na\", \"Cefdinir\", \"Cefditoren Pivoxil\", \"Cefixime\", \"Ceftibuten\", \"Ceftizoxim\\u00b7Na\", \"Ceftriaxone\\u00b7Na\", \"Cefuroxime Axetil\", \"Cefuroxime\\u00b7Na\", \"Cephalexin Monohydrate\", \"Acetohexamide\", \"Acetohydroxamic Acid\", \"Acetylcysteine\", \"Acrivastine\", \"Chlorpropamide\", \"Chlorthalidone\", \"Chlorzoxazone\", \"Blank\", \"Ambrisentan\", \"Amcinonide\", \"Amikacin Disulfate\", \"Cladribine\", \"Clavulanate Potassium\", \"Blank\", \"Artemether\", \"Articaine\\u00b7HCl\", \"L-Ascorbic Acid\", \"Asenapine Maleate\", \"Colistin Sulfate\", \"Cortisone Acetate\", \"Cyclobenzaprine\\u00b7HCl\", \"Baclofen\", \"Balsalazide\", \"Beclomethasone Dipropionate\", \"Benazepril\\u00b7HCl\", \"Daptomycin\", \"Darifenacin\\u00b7HBr\", \"Darunavir\", \"Biperiden\\u00b7HCl\", \"Bisoprolol Fumarate\", \"Brimonidine\", \"Bromfenac \", \"Desonide\", \"Desoximetasone\", \"Desvenlafaxine Succinate Hydrate\", \"Carbinoxamine Maleate\", \"Carglumic Acid\", \"Blank\", \"Carmustine\", \"Dicyclomine\\u00b7HCl\", \"Dienogest\", \"Blank\", \"Cefotetan Disodium\", \"Cefoxitin\\u00b7Na\", \"Cefpodoxime Proxetil\", \"Cefprozil\", \"Doxepin\\u00b7HCl\", \"Droperidol\", \"Drospirenone\", \"Chenodiol (Chenodeoxycholic Acid)\", \"Blank\", \"Chlorhexidine Dihydrochloride\", \"Chlorothiazide\", \"Epirubicin\\u00b7HCl\", \"Eplerenone\", \"Eptifibatide\", \"Ciclesonide\", \"Ciclopirox\", \"Cidofovir\", \"Cilostazol\", \"Cinacalcet\\u00b7HCl\", \"Cisatracurium Besylate\", \"Cisplatin (Cis-Diamineplatinum(Ii) Dichloride )\", \"Clofazimine\", \"Clomipramine\\u00b7HCl\", \"Blank\", \"Clotrimazole\", \"Cloxacillin\\u00b7Na \", \"Colchicine\", \"Colistimethate\\u00b7Na\", \"Cyclopentolate \", 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\"Everolimus\", \"Ezetimibe\", \"Flavoxate\\u00b7HCl\", \"Flucytosine\", \"Fludarabine Phosphate\", \"Fludrocortisone Acetate\", \"Flunisolide\", \"Fluocinonide\", \"Fluorometholone\", \"Fluvoxamine Maleate\", \"Fomepizole\", \"Formoterol\", \"Foscarnet\\u00b7Na (Sodium Phosphonoformate Tribasic Hexahydrate) \", \"Fosfomycin Calcium\", \"Fosphenytoin\\u00b7Na Pentahydrate\", \"Gemifloxacin \", \"Halcinonide\", \"Halobetasol Propionate\", \"Hexachlorophene\", \"Homatropine Methylbromide\", \"Hydralazine\\u00b7HCl\", \"Hydrochlorothiazide\", \"Hydroflumethiazide\", \"Hydroxyzine Dihydrochloride\", \"Ibutilide Fumarate\", \"Iloperidone\", \"Indinavir \", \"Irbesartan\", \"Irinotecan\\u00b7HCl\", \"Isocarboxazid\", \"Kanamycin Sulfate\", \"Ketorolac Tromethamine\", \"Labetalol\\u00b7HCl\", \"Lacosamide\", \"Lactulose\", \"Lamivudine\", \"Lansoprazole\", \"Levobunolol\\u00b7HCl\", \"Levocarnitine\", \"Levocetirizine Dihydrochloride\", \"Levothyroxine\\u00b7Na\", \"Blank\", \"Liothyronine\\u00b7Na\", \"Lopinavir\", \"Mafenide\\u00b7HCl\", \"Malathion\", \"Mannitol\", \"Maraviroc\", \"blank\", \"Meclizine Dihydrochloride\", \"Meclofenamate\\u00b7Na\", \"Febuxostat\", \"Fexofenadine\\u00b7HCl\", \"Fingolimod\", \"Blank\", \"Mequinol\", \"Mercaptopurine Hydrate\", \"Mesna\", \"Flurandrenolide\", \"Blank\", \"Fluticasone Propionate\", \"Methenamine Hippurate\", \"Methocarbamol\", \"Methotrexate \", \"Methoxsalen (Xanthotoxin)\", \"Glycopyrrolate Iodide\", \"Griseofulvin\", \"Guanidine\\u00b7HCl\", \"Metyrapone\", \"Blank\", \"Mexiletine\\u00b7HCl\", \"Micafungin \", \"Hydroxocobalamin\\u00b7HCl\", \"Hydroxychloroquine Sulfate\", \"Hydroxyurea\", \"Mitotane\", \"Blank\", \"Moexipril\\u00b7HCl\", \"Mometasone Furoate\", \"Isosorbide Dinitrate\", \"Isotretinoin (13-Cis-Retinoic Acid)\", \"Isradipine\", \"Nebivolol\\u00b7HCl\", \"Nelarabine\", \"Nepafenac\", \"Nevirapine\", \"Lenalidomide\", \"Leucovorin Calcium Pentahydrate\", \"Levalbuterol\\u00b7HCl\", \"Nitrofurantoin\", \"Nizatidine\", \"Nortriptyline\\u00b7HCl\", \"Olsalazine\\u00b7Na\", \"Blank\", \"Loteprednol Etabonate\", \"Loxapine Succinate\", \"Paliperidone\", \"Palonosetron\\u00b7HCl\", \"Paromomycin Sulfate\", \"Pazopanib\\u00b7HCl\", \"Mefloquine\\u00b7HCl\", \"Mepenzolate Bromide\", \"Mepivacaine\\u00b7HCl\", \"Perindopril Erbumine\", \"Permethrin\", \"Perphenazine\", \"Phenelzine Sulfate\", \"Mestranol\", \"Metaproterenol Hemisulfate (Orciprenaline)\", \"Metaraminol Bitartrate\", \"Metaxalone\", \"Methacholine Chloride\", \"Methazolamide\", \"Posaconazole\", \"Methscopolamine Bromide ((\\u2212)-Scopolamine Methyl Bromide)\", \"Methsuximide\", \"Methyclothiazide\", \"Methyl Aminolevulinate\\u00b7HCl\", \"Methylergonovine Maleate\", \"Metolazone\", \"Propylthiouracil\", \"Miconazole\", \"Blank\", \"Midodrine\\u00b7HCl\", \"Miglitol\", \"Milnacipran\\u00b7HCl\", \"Mirtazapine\", \"Regadenoson\", \"Mupirocin\", \"Nadolol\", \"Nafcillin\\u00b7Na\", \"Naftifine\\u00b7HCl\", 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\"Rabeprazole\\u00b7Na\", \"Raltegravir\", \"Repaglinide\", \"Reserpine\", \"Rifabutin\", \"Rifapentine\", \"Rifaximin\", \"Ritonavir\", \"Rizatriptan Benzoate\", \"Rufinamide\", \"Saquinavir Mesylate\", \"Blank\", \"Sertraline\\u00b7HCl\", \"Silver Sulfadiazine\", \"Sitagliptin Phosphate\", \"Sorafenib Tosylate\", \"Sulfacetamide\\u00b7Na\", \"Sulfamethoxazole\", \"Sulfanilamide\", \"Blank\", \"Tacrolimus (Fk506)\", \"Tadalafil\", \"Tazarotene\", \"Blank\", \"Teniposide\", \"Tenofovir\", \"Terbutaline Hemisulfate\", \"Terconazole\", \"Testosterone Enanthate\", \"Tetrabenazine\", \"Thiotepa\", \"Blank\", \"Tiagabine\\u00b7HCl\", \"Tigecycline\", \"Tiludronate Disodium\", \"Tiopronin\", \"Tirofiban\\u00b7HCl\", \"Torsemide\", \"Trandolapril\", \"Travoprost\", \"Trazodone\\u00b7HCl\", \"Tretinoin\", \"Triamcinolone Acetonide\", \"Triamterene\", \"Blank\", \"Proparacaine\\u00b7HCl\", \"Trihexyphenidyl\\u00b7HCl\", \"Valsartan\", \"Ziprasidone \", \"Ramelteon\", \"Rasagiline Mesylate\", 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\"Phentolamine\\u00b7HCl\", \"Quinine\\u00b7HCl\\u00b7H2O\", \"Propafenone\\u00b7HCl\", \"Flecainide Acetate\", \"Rosiglitazone \", \"Amantadine\\u00b7HCl\", \"Prazosin\\u00b7HCl\", \"Clonidine\\u00b7HCl\", \"Guanabenz Acetate \", \"Dihydroergotamine Mesylate\", \"(S)-Timolol Maleate\", \"Salbutamol Hemisulfate\", \"Pindolol\", \"Dobutamine\\u00b7HCl\", \"Sotalol\\u00b7HCl\", \"Maprotiline\\u00b7HCl\", \"Pilocarpine\\u00b7HCl\", \"Ivermectin\", \"Haloperidol \", \"Cimetidine\", \"Zonisamide\", \"Zoledronic Acid Monohydrate\", \"Naltrexone\\u00b7HCl\", \"Zolmitriptan\", \"Aminophylline \", \"Nateglinide\", \"(\\u00b1) Isoproterenol\\u00b7HCl \", \"Acetylcholine Chloride\", \"Atropine Sulfate Monohydrate\", \"Apomorphine\\u00b7HCl Hemihydrate\", \"Chlorpromazine\\u00b7HCl\", \"Promethazine\\u00b7HCl\", \"Ranitidine\\u00b7HCl\", \"Epinephrine (L-(-)-Epinephrine-(+)-Bitartrate)\", \"Norepinephrine Bitartrate Monohydrate\", \"Quetiapine Fumarate\", \"Imipramine\\u00b7HCl\", \"Amoxapine\", \"Famotidine\", \"Isoniazid\", \"Ticlopidine\\u00b7HCl\", \"Clemastine Fumarate\", \"Vardenafil \", \"Blank\", \"Docetaxel (Taxotere)\", \"Spectinomycin\\u00b7HCl Pentahydrate\", \"Amiodarone\\u00b7HCl\", \"Nicardipine\\u00b7HCl\", \"Nisoldipine\", \"Olanzapine\", \"Lovastatin\", \"Lamotrigine\", \"Phenytoin\", \"Procainamide\\u00b7HCl\", \"Lidocaine\\u00b7HCl\\u00b7H2O\", \"Candesartan\", \"Butenafine\\u00b7HCl\", \"Dorzolamide\\u00b7HCl\", \"Escitalopram \", \"Emtricitabine\", \"Betaxolol\\u00b7HCl\", \"Caffeine \", \"Flumazenil\", \"Gefitinib\", \"Imatinib Mesylate\", \"Idarubicin\\u00b7HCl\", \"Ipratropium\\u00b7Br\", \"Tropicamide\", \"Pancuronium\\u00b72Br\", \"Erlotinib\", \"Tacrine\\u00b7HCl\", \"Galantamine\\u00b7HBr\", \"Amiloride\\u00b7HCl\\u00b72H2O\", \"Memantine\\u00b7HCl\", \"Riluzole\\u00b7HCl\", \"Propofol\", \"Felodipine\", \"Phenoxybenzamine\\u00b7HCl\", \"Trifluoperazine\\u00b7HCl\", \"Latanoprost\", \"Fluphenazine\\u00b7HCl\", \"Risperidone\", \"Diphenhydramine\\u00b7HCl\", \"Cromolyn\\u00b7Na (Disodium Cromoglycate)\", \"Capsaicin\", \"Dexamethasone\", \"Dipyridamole\", \"Metoclopramide\\u00b7HCl\", \"Nalbuphine\\u00b7HCl Dihydrate\", \"Carbachol (Carbamylcholine ) Chloride\", \"Auranofin\", \"Captopril\", \"Tranylcypromine Hemisulfate\", \"Piroxicam\", \"Olopatadine\", \"Tolcapone\", \"Olmesartan\", \"Simvastatin\", \"Goserelin Acetate\", \"Raloxifene\\u00b7HCl\", \"Rifampin (Rifampicin)\", \"Azathioprine\", \"Sildenafil Citrate\", \"Atovaquone\", \"Sertaconazole\", \"Cefepime\\u00b7HCl Hydrate\", \"Aripiprazole\", \"Lapatinib Ditosylate\", \"Eprosartan Mesylate\", \"Entacapone\", \"Bleomycin Sulfate\", \"Guanfacine\\u00b7HCl\", \"Tizanidine\\u00b7HCl\", \"Carvedilol\", \"Diazoxide\", \"Montelukast\\u00b7Na\", \"Exemestane\", \"Dinoprostone\", \"Metformin\\u00b7HCl\", \"Anagrelide\", \"Dofetilide\", \"Bicalutamide\", \"Amlodipine\", \"Diltiazem\\u00b7HCl\", \"Nifedipine\", \"Nimodipine\", \"Verapamil\\u00b7HCl\", \"Gabapentin\", \"Oxaliplatin\", \"Alfuzosin\", \"Bromocriptine Mesylate\", \"Clozapine\", \"Acitretin\", \"Calcitriol\", \"Ketoconazole\", \"Oseltamivir Phosphate\", \"Ethacrynic Acid\", \"Indomethacin\", \"Naproxen\", \"Ibuprofen\", \"Bumetanide\", \"Neomycin Sulfate\", \"Acyclovir (Acycloguanosine) Zovirax\", \"Moxifloxacin\\u00b7HCl\", \"Carbidopa\", \"Ketoprofen\", \"Meloxicam\", \"Terbinafine\\u00b7HCl\", \"Sodium Phenylbutyrate\", \"Ampicillin Trihydrate\", \"Etoposide\", \"Mitomycin C\", \"Delavirdine Mesylate\", \"Daunorubicin\\u00b7HCl\", \"Doxorubicin\\u00b7HCl\", \"Cetirizine 2HCl\", \"Carbamazepine\", \"Pioglitazone\\u00b7HCl\", \"Rivastigmine Tartrate\", \"Blank\", \"Sulindac\", \"Valproic Acid\", \"Calcipotriene\", \"Zafirlukast\", \"Glyburide\", \"Minoxidil\", \"Tolazamide\", \"Bexarotene\", \"Tranexamic Acid\", \"Blank\", \"Levetiracetam\", \"Clindamycin Palmitate\\u00b7HCl\", \"Vorinostat\", \"Didanosine\", \"Dolasetron\", \"Enalaprilat Maleate\", \"Fluvastatin\\u00b7Na\", \"Fosinopril\\u00b7Na\", \"Atazanavir\", \"Mycophenolate Mofetil\", \"Clofarabine\", \"Cabergoline\", \"Ibandronate\\u00b7Na Monohydrate\", \"Imipenem\", \"Lomustine\", \"Pamidronate Disodium  Pentahydrate (Pamidronic Acid)\", \"Pramipexole Dihydrochloride Monohydrate\", \"Triptorelin Acetate\", \"Risredonic Acid\", \"Rocuronium Bromide\", \"Vinorelbine \", \"Salmeterol \", \"Zidovudine (3'-Azido-3'-Deoxythymidine)\", \"Allopurinol\", \"Altretamine\", \"Alendronate\\u00b7Na Trihydrate\", \"Albendazole\", \"Sumatriptan Succinate\", \"Amifostine\", \"(\\u00b1)-Atenolol\", \"Atracurium Besylate\", \"Vinblastine Sulfate\", \"Azithromycin\", \"Aztreonam\", \"Betamethasone\", \"Bisacodyl\", \"Cefotaxime Acid\", \"Ceftazidime\", \"Chloramphenicol\", \"Chlorambucil\", \"Chlorpheniramine Maleate\", \"Chloroquine Diphosphate\", \"Thalidomide\", \"Zileuton\", \"Bortezomib\", \"Clarithromycin\", \"Clomiphene Citrate\", \"Clopidogrel Hydrogen Sulfate \", \"Clobetasol Propionate\", \"Orphenadrine Citrate\", \"Letrozole\", \"Anastrozole\", \"Desloratadine\", \"Dextromethorphan\", \"Diclofenac\\u00b7Na Salt\", \"Zalcitabine (2',3'-Dideoxycytidine)\", \"Diflunisal\", \"Gemcitabine\\u00b7HCl\", \"Granisetron\\u00b7HCl\", \"Estradiol\", \"Estrone\", \"Etidronate Disodium\", \"Famciclovir\", \"Fenoldopam Mesylate\", \"Adapalene\", \"Meropenem\", \"Amitriptyline\\u00b7HCl\", \"Floxuridine\", \"Fluocinolone Acetonide\", \"Flutamide\", \"Fluconazole\", \"Vincristine Sulfate\", \"Aspirin (Acetylsalicylic Acid)\", \"Glimepiride\", \"Hydrocortisone\", \"Hydrocortisone Acetate\", \"Idoxuridine\", \"Ifosfamide\", \"4-Aminosalicylic Acid\", \"Mesalamine (5-Aminosalicylic Acid)\", \"Leflunomide\", \"Lisinopril\\u00b72H2O\", \"Loratadine\", \"Losartan Potassium\", \"Mebendazole\", \"Buspirone\\u00b7HCl\", \"Carboplatin\", \"Metoprolol Tartrate\", \"Methimazole\", \"Metronidazole\", \"Minocycline \", \"Mitoxantrone\\u00b7HCl\", \"Ciprofloxacin\", \"Citalopram\\u00b7HBr\", \"Norfloxacin\", \"Nystatin\", \"Ofloxacin\", \"Omeprazole\", \"Oxcarbazepine\", \"Crotamiton\", \"Cyclophosphamide (Free Base)\", \"Cytarabine\", \"Dacarbazine\", \"Danazol\", \"Pentoxifylline\", \"Penicillin V Potassium\", \"Disulfiram\", \"Doxazosin Mesylate\", \"Doxycycline Monohydrate\", \"Enalapril\", \"Esomeprazole Potassium\", \"Ranolazine\\u00b72HCl\", \"Ramipril\", \"Fenoprofen Calcium\", \"Fenofibrate\", \"Finasteride\", \"Fluorouracil (5-Fluorouracil)\", \"Flurbiprofen\", \"Sulfasalazine\", \"Tamsulosin\\u00b7HCl\", \"Furosemide\", \"Ganciclovir\", \"Gatifloxacin\", \"Gentamycin Sulfate\", \"Gemfibrozil\", \"Tolmetin\\u00b7Na\", \"Amoxicillin\", \"Imiquimod\", \"Indapamide\", \"Itraconazole\", \"Levonorgestrel\", \"Levofloxacin\\u00b7HCl\", \"Fluoxetine\\u00b7HCl\", \"Ondansetron\", \"Medroxyprogesterone Acetate\", \"Mefenamic Acid\", \"Melphalan\", \"Methyldopa Sesquihydrate (L-\\u0391-Methyl-Dopa Sesquihyrate)\", \"Methylprednisolone\", \"Butoconazole Nitrate\", \"Mifepristone\", \"Paclitaxel (Taxol)\", \"Nabumetone\", \"Naphazoline\\u00b7HCl\", \"Nefazodone\\u00b7HCl\", \"Norethindrone\", \"Capecitabine\", \"Succinylcholine Chloride\\u00b72H2O\", \"Oxiconazole Nitrate\", \"Oxacillin\\u00b7Na\", \"Pantoprazole\", \"Paroxetine\\u00b7HCl\", \"Penciclovir\", \"Piperacillin\", \"Prednisolone\", \"Progesterone\", \"Procarbazine\\u00b7HCl\", \"Prednisone\", \"Primaquine Phosphate\", \"Praziquantel\", \"Ribavirin\", \"Nelfinavir Mesylate\", \"Rimantadine\\u00b7HCl\", \"Propranolol\\u00b7HCl\", \"Scopolamine\\u00b7HBr\", \"Spironolactone\", \"Streptomycin Sulfate\", \"Telmisartan\", \"Terazosin\\u00b7HCl\", \"Tetracycline\", \"Temozolomide\", \"Tinidazole\", \"Tobramycin\", \"Topotecan\\u00b7HCl\", \"Tramadol\\u00b7HCl\", \"Trimethoprim\", \"Valacyclovir\\u00b7HCl\", \"Vecuronium Bromide\", \"Venlafaxine\\u00b7HCl\", \"Bupivacaine\\u00b7HCl\", \"Ketotifen Fumarate\", \"Tiotropium Bromide Monohydrate\", \"Thioridazine\\u00b7HCl\", \"Amrinone\", \"Milrinone\", \"Alprostadil\", \"Misoprostol\", \"Argatroban\", \"Megestrol Acetate\", \"Tamoxifen Citrate\", \"Aprepitant\", \"Bosentan\", \"Efavirenz\", \"Miglustat (N-Butyldeoxynojirimycin\\u00b7HCl)\", \"Fulvestrant\", \"Cyproheptadine\\u00b7HCl Sesquihydrate\", \"Quinapril\\u00b7HCl\", \"Abacavir Sulfate\", \"Acamprosate \", \"Acarbose\", \"Acebutolol\\u00b7HCl\", \"Acetaminophen\", \"Acetazolamide\", \"Sulfadiazine\", \"Adefovir Dipivoxil\", \"Adenosine\", \"Blank\", \"Alitretinoin\", \"Almotriptan\", \"Alosetron\\u00b7HCl\", \"Toremifene Base\", \"Aminocaproic Acid\", \"Aminohippurate\\u00b7Na\", \"Aminolevulinic Acid\\u00b7HCl\", \"Amlexanox\", \"Amphotericin B\", \"Arsenic Trioxide\", \"Naloxone\\u00b7HCl\", \"Atomoxetine\\u00b7HCl\", \"Atorvastatin Calcium\", \"Azacitidine\", \"Azelaic Acid\", \"Azelastine\\u00b7HCl\", \"Bacitracin\", \"Cilastatin\\u00b7Na\", \"Bendamustine\\u00b7HCl\", \"Bendroflumethiazide\", \"Benztropine Mesylate\", \"Betaine \", \"Bethanechol Chloride\", \"Bimatoprost\", \"Esmolol\", \"Brompheniramine Maleate\", \"Budesonide\", \"Bupropion \", \"Busulfan\", \"Butorphanol-(+)-Tartrate (Schedule Iv)\", \"Capreomycin Sulfate\", \"Cefaclor\", \"Cefadroxil\", \"Cefazolin\\u00b7Na\", \"Cefdinir\", \"Cefditoren Pivoxil\", \"Cefixime\", \"Ceftibuten\", \"Ceftizoxim\\u00b7Na\", \"Ceftriaxone\\u00b7Na\", \"Cefuroxime Axetil\", \"Cefuroxime\\u00b7Na\", \"Cephalexin Monohydrate\", \"Acetohexamide\", \"Acetohydroxamic Acid\", \"Acetylcysteine\", \"Acrivastine\", \"Chlorpropamide\", \"Chlorthalidone\", \"Chlorzoxazone\", \"Blank\", \"Ambrisentan\", \"Amcinonide\", \"Amikacin Disulfate\", \"Cladribine\", \"Clavulanate Potassium\", \"Blank\", \"Artemether\", \"Articaine\\u00b7HCl\", \"L-Ascorbic Acid\", \"Asenapine Maleate\", \"Colistin Sulfate\", \"Cortisone Acetate\", \"Cyclobenzaprine\\u00b7HCl\", \"Baclofen\", \"Balsalazide\", \"Beclomethasone Dipropionate\", \"Benazepril\\u00b7HCl\", 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Acetate\", \"Flunisolide\", \"Fluocinonide\", \"Fluorometholone\", \"Fluvoxamine Maleate\", \"Fomepizole\", \"Formoterol\", \"Foscarnet\\u00b7Na (Sodium Phosphonoformate Tribasic Hexahydrate) \", \"Fosfomycin Calcium\", \"Fosphenytoin\\u00b7Na Pentahydrate\", \"Gemifloxacin \", \"Halcinonide\", \"Halobetasol Propionate\", \"Hexachlorophene\", \"Homatropine Methylbromide\", \"Hydralazine\\u00b7HCl\", \"Hydrochlorothiazide\", \"Hydroflumethiazide\", \"Hydroxyzine Dihydrochloride\", \"Ibutilide Fumarate\", \"Iloperidone\", \"Indinavir \", \"Irbesartan\", \"Irinotecan\\u00b7HCl\", \"Isocarboxazid\", \"Kanamycin Sulfate\", \"Ketorolac Tromethamine\", \"Labetalol\\u00b7HCl\", \"Lacosamide\", \"Lactulose\", \"Lamivudine\", \"Lansoprazole\", \"Levobunolol\\u00b7HCl\", \"Levocarnitine\", \"Levocetirizine Dihydrochloride\", \"Levothyroxine\\u00b7Na\", \"Blank\", \"Liothyronine\\u00b7Na\", \"Lopinavir\", \"Mafenide\\u00b7HCl\", \"Malathion\", \"Mannitol\", \"Maraviroc\", \"blank\", \"Meclizine 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Succinate\", \"Paliperidone\", \"Palonosetron\\u00b7HCl\", \"Paromomycin Sulfate\", \"Pazopanib\\u00b7HCl\", \"Mefloquine\\u00b7HCl\", \"Mepenzolate Bromide\", \"Mepivacaine\\u00b7HCl\", \"Perindopril Erbumine\", \"Permethrin\", \"Perphenazine\", \"Phenelzine Sulfate\", \"Mestranol\", \"Metaproterenol Hemisulfate (Orciprenaline)\", \"Metaraminol Bitartrate\", \"Metaxalone\", \"Methacholine Chloride\", \"Methazolamide\", \"Posaconazole\", \"Methscopolamine Bromide ((\\u2212)-Scopolamine Methyl Bromide)\", \"Methsuximide\", \"Methyclothiazide\", \"Methyl Aminolevulinate\\u00b7HCl\", \"Methylergonovine Maleate\", \"Metolazone\", \"Propylthiouracil\", \"Miconazole\", \"Blank\", \"Midodrine\\u00b7HCl\", \"Miglitol\", \"Milnacipran\\u00b7HCl\", \"Mirtazapine\", \"Regadenoson\", \"Mupirocin\", \"Nadolol\", \"Nafcillin\\u00b7Na\", \"Naftifine\\u00b7HCl\", \"Naratriptan\\u00b7HCl\", \"Natamycin\", \"Rosuvastatin Calcium\", \"Niacin (Known As Vitamin B3, Nicotinic Acid And Vitamin Pp) \", 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\"Rizatriptan Benzoate\", \"Rufinamide\", \"Saquinavir Mesylate\", \"Blank\", \"Sertraline\\u00b7HCl\", \"Silver Sulfadiazine\", \"Sitagliptin Phosphate\", \"Sorafenib Tosylate\", \"Sulfacetamide\\u00b7Na\", \"Sulfamethoxazole\", \"Sulfanilamide\", \"Blank\", \"Tacrolimus (Fk506)\", \"Tadalafil\", \"Tazarotene\", \"Blank\", \"Teniposide\", \"Tenofovir\", \"Terbutaline Hemisulfate\", \"Terconazole\", \"Testosterone Enanthate\", \"Tetrabenazine\", \"Thiotepa\", \"Blank\", \"Tiagabine\\u00b7HCl\", \"Tigecycline\", \"Tiludronate Disodium\", \"Tiopronin\", \"Tirofiban\\u00b7HCl\", \"Torsemide\", \"Trandolapril\", \"Travoprost\", \"Trazodone\\u00b7HCl\", \"Tretinoin\", \"Triamcinolone Acetonide\", \"Triamterene\", \"Blank\", \"Proparacaine\\u00b7HCl\", \"Trihexyphenidyl\\u00b7HCl\", \"Valsartan\", \"Ziprasidone \", \"Ramelteon\", \"Rasagiline Mesylate\", \"Trimethadione\", \"Vancomycin\\u00b7HCl\", \"Ropinirole\\u00b7HCl\", \"Ropivacaine\\u00b7HCl Monohydrate\", \"Trimethobenzamide\\u00b7HCl\", \"Blank\", \"Stavudine\", \"Streptozocin\", \"Trimipramine Maleate\", \"Vigabatrin\", \"Telbivudine \", \"Telithromycin\", \"Trospium Chloride\", \"Voriconazole\", \"Tetrahydrozoline\\u00b7HCl\", \"Theophylline\", \"Ursodiol\", \"Warfarin\\u00b7Na\", \"Tolterodine Tartrate\", \"Tolvaptan\", \"Valganciclovir\\u00b7HCl\", \"Zaleplon\", \"Blank\", \"Trientine Dihydrochloride\", \"Valproate\\u00b7Na\", \"Zanamivir\"], \"legendgroup\": \"\", \"marker\": {\"color\": \"#636efa\", \"symbol\": \"circle\"}, \"mode\": \"markers\", \"name\": \"\", \"showlegend\": false, \"type\": \"scattergl\", \"x\": [\"Clindamycin\\u00b7HCl\", \"Felbamate\", \"Cyclosporine A\", \"Donepezil\\u00b7HCl\", \"Lincomycin\\u00b7HCl\", \"Mycophenolic Acid\", \"Sirolimus (Rapamycin)\", \"Pimozide\", \"Loperamide\\u00b7HCl\", \"Tolbutamide\", \"Glipizide\", \"Phentolamine\\u00b7HCl\", \"Quinine\\u00b7HCl\\u00b7H2O\", \"Propafenone\\u00b7HCl\", \"Flecainide Acetate\", \"Rosiglitazone \", \"Amantadine\\u00b7HCl\", \"Prazosin\\u00b7HCl\", \"Clonidine\\u00b7HCl\", \"Guanabenz Acetate \", \"Dihydroergotamine Mesylate\", \"(S)-Timolol Maleate\", \"Salbutamol Hemisulfate\", \"Pindolol\", \"Dobutamine\\u00b7HCl\", \"Sotalol\\u00b7HCl\", \"Maprotiline\\u00b7HCl\", \"Pilocarpine\\u00b7HCl\", \"Ivermectin\", \"Haloperidol \", \"Cimetidine\", \"Zonisamide\", \"Zoledronic Acid Monohydrate\", \"Naltrexone\\u00b7HCl\", \"Zolmitriptan\", \"Aminophylline \", \"Nateglinide\", \"(\\u00b1) Isoproterenol\\u00b7HCl \", \"Acetylcholine Chloride\", \"Atropine Sulfate Monohydrate\", \"Apomorphine\\u00b7HCl Hemihydrate\", \"Chlorpromazine\\u00b7HCl\", \"Promethazine\\u00b7HCl\", \"Ranitidine\\u00b7HCl\", \"Epinephrine (L-(-)-Epinephrine-(+)-Bitartrate)\", \"Norepinephrine Bitartrate Monohydrate\", \"Quetiapine Fumarate\", \"Imipramine\\u00b7HCl\", \"Amoxapine\", \"Famotidine\", \"Isoniazid\", \"Ticlopidine\\u00b7HCl\", \"Clemastine Fumarate\", \"Vardenafil \", \"Blank\", \"Docetaxel (Taxotere)\", \"Spectinomycin\\u00b7HCl Pentahydrate\", \"Amiodarone\\u00b7HCl\", \"Nicardipine\\u00b7HCl\", \"Nisoldipine\", \"Olanzapine\", \"Lovastatin\", \"Lamotrigine\", \"Phenytoin\", \"Procainamide\\u00b7HCl\", \"Lidocaine\\u00b7HCl\\u00b7H2O\", \"Candesartan\", \"Butenafine\\u00b7HCl\", \"Dorzolamide\\u00b7HCl\", \"Escitalopram \", \"Emtricitabine\", \"Betaxolol\\u00b7HCl\", \"Caffeine \", \"Flumazenil\", \"Gefitinib\", \"Imatinib Mesylate\", \"Idarubicin\\u00b7HCl\", \"Ipratropium\\u00b7Br\", \"Tropicamide\", \"Pancuronium\\u00b72Br\", \"Erlotinib\", \"Tacrine\\u00b7HCl\", \"Galantamine\\u00b7HBr\", \"Amiloride\\u00b7HCl\\u00b72H2O\", \"Memantine\\u00b7HCl\", \"Riluzole\\u00b7HCl\", \"Propofol\", \"Felodipine\", \"Phenoxybenzamine\\u00b7HCl\", \"Trifluoperazine\\u00b7HCl\", \"Latanoprost\", \"Fluphenazine\\u00b7HCl\", \"Risperidone\", \"Diphenhydramine\\u00b7HCl\", \"Cromolyn\\u00b7Na (Disodium Cromoglycate)\", \"Capsaicin\", \"Dexamethasone\", \"Dipyridamole\", \"Metoclopramide\\u00b7HCl\", \"Nalbuphine\\u00b7HCl Dihydrate\", \"Carbachol (Carbamylcholine ) Chloride\", \"Auranofin\", \"Captopril\", \"Tranylcypromine Hemisulfate\", \"Piroxicam\", \"Olopatadine\", \"Tolcapone\", \"Olmesartan\", \"Simvastatin\", \"Goserelin Acetate\", \"Raloxifene\\u00b7HCl\", \"Rifampin (Rifampicin)\", \"Azathioprine\", \"Sildenafil Citrate\", \"Atovaquone\", \"Sertaconazole\", \"Cefepime\\u00b7HCl Hydrate\", \"Aripiprazole\", \"Lapatinib Ditosylate\", \"Eprosartan Mesylate\", \"Entacapone\", \"Bleomycin Sulfate\", \"Guanfacine\\u00b7HCl\", \"Tizanidine\\u00b7HCl\", \"Carvedilol\", \"Diazoxide\", \"Montelukast\\u00b7Na\", \"Exemestane\", \"Dinoprostone\", \"Metformin\\u00b7HCl\", \"Anagrelide\", \"Dofetilide\", \"Bicalutamide\", \"Amlodipine\", \"Diltiazem\\u00b7HCl\", \"Nifedipine\", \"Nimodipine\", \"Verapamil\\u00b7HCl\", \"Gabapentin\", \"Oxaliplatin\", \"Alfuzosin\", \"Bromocriptine Mesylate\", \"Clozapine\", \"Acitretin\", \"Calcitriol\", \"Ketoconazole\", \"Oseltamivir Phosphate\", \"Ethacrynic Acid\", \"Indomethacin\", \"Naproxen\", \"Ibuprofen\", \"Bumetanide\", \"Neomycin Sulfate\", \"Acyclovir (Acycloguanosine) Zovirax\", \"Moxifloxacin\\u00b7HCl\", \"Carbidopa\", \"Ketoprofen\", \"Meloxicam\", \"Terbinafine\\u00b7HCl\", \"Sodium Phenylbutyrate\", \"Ampicillin Trihydrate\", \"Etoposide\", \"Mitomycin C\", \"Delavirdine Mesylate\", \"Daunorubicin\\u00b7HCl\", \"Doxorubicin\\u00b7HCl\", \"Cetirizine 2HCl\", \"Carbamazepine\", \"Pioglitazone\\u00b7HCl\", \"Rivastigmine Tartrate\", \"Blank\", \"Sulindac\", \"Valproic Acid\", \"Calcipotriene\", \"Zafirlukast\", \"Glyburide\", \"Minoxidil\", \"Tolazamide\", \"Bexarotene\", \"Tranexamic Acid\", \"Blank\", \"Levetiracetam\", \"Clindamycin Palmitate\\u00b7HCl\", \"Vorinostat\", \"Didanosine\", \"Dolasetron\", \"Enalaprilat Maleate\", \"Fluvastatin\\u00b7Na\", \"Fosinopril\\u00b7Na\", \"Atazanavir\", \"Mycophenolate Mofetil\", \"Clofarabine\", \"Cabergoline\", \"Ibandronate\\u00b7Na Monohydrate\", \"Imipenem\", \"Lomustine\", \"Pamidronate Disodium  Pentahydrate (Pamidronic Acid)\", \"Pramipexole Dihydrochloride Monohydrate\", \"Triptorelin Acetate\", \"Risredonic Acid\", \"Rocuronium Bromide\", \"Vinorelbine \", \"Salmeterol \", \"Zidovudine (3'-Azido-3'-Deoxythymidine)\", \"Allopurinol\", \"Altretamine\", \"Alendronate\\u00b7Na Trihydrate\", \"Albendazole\", \"Sumatriptan Succinate\", \"Amifostine\", \"(\\u00b1)-Atenolol\", \"Atracurium Besylate\", \"Vinblastine Sulfate\", \"Azithromycin\", \"Aztreonam\", \"Betamethasone\", \"Bisacodyl\", \"Cefotaxime Acid\", \"Ceftazidime\", \"Chloramphenicol\", \"Chlorambucil\", \"Chlorpheniramine Maleate\", \"Chloroquine Diphosphate\", \"Thalidomide\", \"Zileuton\", \"Bortezomib\", \"Clarithromycin\", \"Clomiphene Citrate\", \"Clopidogrel Hydrogen Sulfate \", \"Clobetasol Propionate\", \"Orphenadrine Citrate\", \"Letrozole\", \"Anastrozole\", \"Desloratadine\", \"Dextromethorphan\", \"Diclofenac\\u00b7Na Salt\", \"Zalcitabine (2',3'-Dideoxycytidine)\", \"Diflunisal\", \"Gemcitabine\\u00b7HCl\", \"Granisetron\\u00b7HCl\", \"Estradiol\", \"Estrone\", \"Etidronate Disodium\", \"Famciclovir\", \"Fenoldopam Mesylate\", \"Adapalene\", \"Meropenem\", \"Amitriptyline\\u00b7HCl\", \"Floxuridine\", \"Fluocinolone Acetonide\", \"Flutamide\", \"Fluconazole\", \"Vincristine Sulfate\", \"Aspirin (Acetylsalicylic Acid)\", \"Glimepiride\", \"Hydrocortisone\", \"Hydrocortisone Acetate\", \"Idoxuridine\", \"Ifosfamide\", \"4-Aminosalicylic Acid\", \"Mesalamine (5-Aminosalicylic Acid)\", \"Leflunomide\", \"Lisinopril\\u00b72H2O\", \"Loratadine\", \"Losartan Potassium\", \"Mebendazole\", \"Buspirone\\u00b7HCl\", \"Carboplatin\", \"Metoprolol Tartrate\", \"Methimazole\", \"Metronidazole\", \"Minocycline \", \"Mitoxantrone\\u00b7HCl\", \"Ciprofloxacin\", \"Citalopram\\u00b7HBr\", \"Norfloxacin\", \"Nystatin\", \"Ofloxacin\", \"Omeprazole\", \"Oxcarbazepine\", \"Crotamiton\", \"Cyclophosphamide (Free Base)\", \"Cytarabine\", \"Dacarbazine\", \"Danazol\", \"Pentoxifylline\", \"Penicillin V Potassium\", \"Disulfiram\", \"Doxazosin Mesylate\", \"Doxycycline Monohydrate\", \"Enalapril\", \"Esomeprazole Potassium\", \"Ranolazine\\u00b72HCl\", \"Ramipril\", \"Fenoprofen Calcium\", \"Fenofibrate\", \"Finasteride\", \"Fluorouracil (5-Fluorouracil)\", \"Flurbiprofen\", \"Sulfasalazine\", \"Tamsulosin\\u00b7HCl\", \"Furosemide\", \"Ganciclovir\", \"Gatifloxacin\", \"Gentamycin Sulfate\", \"Gemfibrozil\", \"Tolmetin\\u00b7Na\", \"Amoxicillin\", \"Imiquimod\", \"Indapamide\", \"Itraconazole\", \"Levonorgestrel\", \"Levofloxacin\\u00b7HCl\", \"Fluoxetine\\u00b7HCl\", \"Ondansetron\", \"Medroxyprogesterone Acetate\", \"Mefenamic Acid\", \"Melphalan\", \"Methyldopa Sesquihydrate (L-\\u0391-Methyl-Dopa Sesquihyrate)\", \"Methylprednisolone\", \"Butoconazole Nitrate\", \"Mifepristone\", \"Paclitaxel (Taxol)\", \"Nabumetone\", \"Naphazoline\\u00b7HCl\", \"Nefazodone\\u00b7HCl\", \"Norethindrone\", \"Capecitabine\", \"Succinylcholine Chloride\\u00b72H2O\", \"Oxiconazole Nitrate\", \"Oxacillin\\u00b7Na\", \"Pantoprazole\", \"Paroxetine\\u00b7HCl\", \"Penciclovir\", \"Piperacillin\", \"Prednisolone\", \"Progesterone\", \"Procarbazine\\u00b7HCl\", \"Prednisone\", \"Primaquine Phosphate\", \"Praziquantel\", \"Ribavirin\", \"Nelfinavir Mesylate\", \"Rimantadine\\u00b7HCl\", \"Propranolol\\u00b7HCl\", \"Scopolamine\\u00b7HBr\", \"Spironolactone\", \"Streptomycin Sulfate\", \"Telmisartan\", \"Terazosin\\u00b7HCl\", \"Tetracycline\", \"Temozolomide\", \"Tinidazole\", \"Tobramycin\", \"Topotecan\\u00b7HCl\", \"Tramadol\\u00b7HCl\", \"Trimethoprim\", \"Valacyclovir\\u00b7HCl\", \"Vecuronium Bromide\", \"Venlafaxine\\u00b7HCl\", \"Bupivacaine\\u00b7HCl\", \"Ketotifen Fumarate\", \"Tiotropium Bromide Monohydrate\", \"Thioridazine\\u00b7HCl\", \"Amrinone\", \"Milrinone\", \"Alprostadil\", \"Misoprostol\", \"Argatroban\", \"Megestrol Acetate\", \"Tamoxifen Citrate\", \"Aprepitant\", \"Bosentan\", \"Efavirenz\", \"Miglustat (N-Butyldeoxynojirimycin\\u00b7HCl)\", \"Fulvestrant\", \"Cyproheptadine\\u00b7HCl Sesquihydrate\", \"Quinapril\\u00b7HCl\", \"Abacavir Sulfate\", \"Acamprosate \", \"Acarbose\", \"Acebutolol\\u00b7HCl\", \"Acetaminophen\", \"Acetazolamide\", \"Sulfadiazine\", \"Adefovir Dipivoxil\", \"Adenosine\", \"Blank\", \"Alitretinoin\", \"Almotriptan\", \"Alosetron\\u00b7HCl\", \"Toremifene Base\", \"Aminocaproic Acid\", \"Aminohippurate\\u00b7Na\", \"Aminolevulinic Acid\\u00b7HCl\", \"Amlexanox\", \"Amphotericin B\", \"Arsenic Trioxide\", \"Naloxone\\u00b7HCl\", \"Atomoxetine\\u00b7HCl\", \"Atorvastatin Calcium\", \"Azacitidine\", \"Azelaic Acid\", \"Azelastine\\u00b7HCl\", \"Bacitracin\", \"Cilastatin\\u00b7Na\", \"Bendamustine\\u00b7HCl\", \"Bendroflumethiazide\", \"Benztropine Mesylate\", \"Betaine \", \"Bethanechol Chloride\", \"Bimatoprost\", \"Esmolol\", \"Brompheniramine Maleate\", \"Budesonide\", \"Bupropion \", \"Busulfan\", \"Butorphanol-(+)-Tartrate (Schedule Iv)\", \"Capreomycin Sulfate\", \"Cefaclor\", \"Cefadroxil\", \"Cefazolin\\u00b7Na\", \"Cefdinir\", \"Cefditoren Pivoxil\", \"Cefixime\", \"Ceftibuten\", \"Ceftizoxim\\u00b7Na\", \"Ceftriaxone\\u00b7Na\", \"Cefuroxime Axetil\", \"Cefuroxime\\u00b7Na\", \"Cephalexin Monohydrate\", \"Acetohexamide\", \"Acetohydroxamic Acid\", \"Acetylcysteine\", \"Acrivastine\", \"Chlorpropamide\", \"Chlorthalidone\", \"Chlorzoxazone\", \"Blank\", \"Ambrisentan\", \"Amcinonide\", \"Amikacin Disulfate\", \"Cladribine\", \"Clavulanate Potassium\", \"Blank\", \"Artemether\", \"Articaine\\u00b7HCl\", \"L-Ascorbic Acid\", \"Asenapine Maleate\", \"Colistin Sulfate\", \"Cortisone Acetate\", \"Cyclobenzaprine\\u00b7HCl\", \"Baclofen\", \"Balsalazide\", \"Beclomethasone Dipropionate\", \"Benazepril\\u00b7HCl\", \"Daptomycin\", \"Darifenacin\\u00b7HBr\", \"Darunavir\", \"Biperiden\\u00b7HCl\", \"Bisoprolol Fumarate\", \"Brimonidine\", \"Bromfenac \", \"Desonide\", \"Desoximetasone\", \"Desvenlafaxine Succinate Hydrate\", \"Carbinoxamine Maleate\", \"Carglumic Acid\", \"Blank\", \"Carmustine\", \"Dicyclomine\\u00b7HCl\", \"Dienogest\", \"Blank\", \"Cefotetan Disodium\", \"Cefoxitin\\u00b7Na\", \"Cefpodoxime Proxetil\", \"Cefprozil\", \"Doxepin\\u00b7HCl\", \"Droperidol\", \"Drospirenone\", \"Chenodiol (Chenodeoxycholic Acid)\", \"Blank\", \"Chlorhexidine Dihydrochloride\", \"Chlorothiazide\", \"Epirubicin\\u00b7HCl\", \"Eplerenone\", \"Eptifibatide\", \"Ciclesonide\", \"Ciclopirox\", \"Cidofovir\", \"Cilostazol\", \"Cinacalcet\\u00b7HCl\", \"Cisatracurium Besylate\", \"Cisplatin (Cis-Diamineplatinum(Ii) Dichloride )\", \"Clofazimine\", \"Clomipramine\\u00b7HCl\", \"Blank\", \"Clotrimazole\", \"Cloxacillin\\u00b7Na \", \"Colchicine\", \"Colistimethate\\u00b7Na\", \"Cyclopentolate \", \"Cycloserine\", \"Cysteamine\\u00b7HCl\", \"Dactinomycin (= Actinomycin D)\", \"Dalfampridine (4-Aminopyridine)\", \"Dantrolene\\u00b7Na\", \"Dapsone\", \"Dasatinib\", \"Decitabine\", \"Deferasirox\", \"Deferoxamine Mesylate\", \"Demeclocycline\\u00b7HCl\", \"Desipramine\\u00b7HCl\", \"Desogestrel\", \"Dexchlorpheniramine Maleate\", \"Dexmedetomidine\\u00b7HCl\", \"Blank\", \"Dexrazoxane \", \"Diatrizoate Meglumine\", \"Blank\", \"Dicloxacillin\\u00b7Na Salt Monohydrate\", \"Difluprednate\", \"Digoxin\", \"Dimenhydrinate\", \"Disopyramide \", \"Dopamine\\u00b7HCl\", \"Doripenem\", \"Doxapram\\u00b7HCl\", \"Duloxetine\\u00b7HCl\", \"Dutasteride\", \"Dyphylline\", \"Econazole Nitrate\", \"Blank\", \"Eflornithine\\u00b7HCl\", \"Epinastine\\u00b7HCl\", \"Erythromycin\", \"Estramustine Phosphate\\u00b7Na\", \"Estropipate\", \"Eszopiclone\", \"Ethambutol Dihydrochloride\", \"Blank\", \"Ethinyl Estradiol\", \"Ethionamide\", \"Ethosuximide\", \"Etodolac\", \"Etomidate\", \"Etonogestrel\", \"Everolimus\", \"Ezetimibe\", \"Flavoxate\\u00b7HCl\", \"Flucytosine\", \"Fludarabine Phosphate\", \"Fludrocortisone Acetate\", \"Flunisolide\", \"Fluocinonide\", \"Fluorometholone\", \"Fluvoxamine Maleate\", \"Fomepizole\", \"Formoterol\", \"Foscarnet\\u00b7Na (Sodium Phosphonoformate Tribasic Hexahydrate) \", \"Fosfomycin Calcium\", \"Fosphenytoin\\u00b7Na Pentahydrate\", \"Gemifloxacin \", \"Halcinonide\", \"Halobetasol Propionate\", \"Hexachlorophene\", \"Homatropine Methylbromide\", \"Hydralazine\\u00b7HCl\", \"Hydrochlorothiazide\", \"Hydroflumethiazide\", \"Hydroxyzine Dihydrochloride\", \"Ibutilide Fumarate\", \"Iloperidone\", \"Indinavir \", \"Irbesartan\", \"Irinotecan\\u00b7HCl\", \"Isocarboxazid\", \"Kanamycin Sulfate\", \"Ketorolac Tromethamine\", \"Labetalol\\u00b7HCl\", \"Lacosamide\", \"Lactulose\", \"Lamivudine\", \"Lansoprazole\", \"Levobunolol\\u00b7HCl\", \"Levocarnitine\", \"Levocetirizine Dihydrochloride\", \"Levothyroxine\\u00b7Na\", \"Blank\", \"Liothyronine\\u00b7Na\", \"Lopinavir\", \"Mafenide\\u00b7HCl\", \"Malathion\", \"Mannitol\", \"Maraviroc\", \"blank\", \"Meclizine Dihydrochloride\", \"Meclofenamate\\u00b7Na\", \"Febuxostat\", \"Fexofenadine\\u00b7HCl\", 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       "var outputEl = gd.closest('.output');\n",
       "if (outputEl) {{\n",
       "    x.observe(outputEl, {childList: true});\n",
       "}}\n",
       "\n",
       "                        })\n",
       "                };\n",
       "                });\n",
       "            </script>\n",
       "        </div>"
      ]
     },
     "metadata": {},
     "output_type": "display_data"
    }
   ],
   "source": [
    "fig = px.scatter(\n",
    "    data_frame=screen_df.reset_index(),\n",
    "    x=\"compound_name\",\n",
    "    y=\"period_change\",\n",
    "    facet_row=\"concentration\",\n",
    "    facet_col=\"compound_set\",\n",
    "    hover_name=\"compound_name\",\n",
    "    hover_data=[\"notes\", \"period_before\", \"compound_set\"],\n",
    "    # same y-axis range as Figure 1A of Tamai et al.\n",
    "    range_y=(-2, 5),\n",
    "    labels={\"period_change\": \"Period Change (hours)\", \"concentration\": \"Concentration\"},\n",
    ")\n",
    "fig.update_xaxes(matches=None, showticklabels=False, title_text=None)\n",
    "fig.show(renderer=\"notebook_connected\")"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "Compare to Figure 1A from [Tamai et al](https://doi.org/10.15252/emmm.201708724):\n",
    "\n",
    "> ![Figure 1A from Tamai et al](https://www.embopress.org/cms/asset/8b16fca1-f8a6-4de3-baa1-66924671a46a/emmm201708724-fig-0001-m.jpg)"
   ]
  }
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