PIASO

Precise Integrative Analysis of Single-cell Omics

Current available functionalities

1. side-by-side cell embedding plots, e.g., split by Conditions
2. stacked violin plots for multiple features, including genes and cell metrics
3. perform dimensionality reduction by GDR
4. integration of scRNA-seq datasets by GDR
5. integration of scRNA-seq data and MERFISH data by GDR
6. run clustering on selected cluster(s)

Coming functionalities

1. preprocessing of scATAC-seq datasets
2. integration of scRNA-seq and scATAC-seq datasets (not replying on gene activities)
3. and others

Citation

If PIASO is useful for your research, please consider citing Wu et al., Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes, bioRxiv (2024).

Contact

Min Dai

Email: dai@broadinstitute.org