Transcranial magnetic stimulation (TMS) coil holder for concurrent MRI and TMS

We present a transcranial magnetic stimulation (TMS) holder for concurrent TMS-MRI studies. This holder features one-knob fixation to allow for high degrees of rotations and translation between the TMS coil at the distant end and the holder base at the proximal end via in-plane rotation and omni-direction rotation.

The current design is compatible with 3T MRI scanner from Siemens (Prisma).

Reference: "Design of coil holder for the improved maneuvering in concurrent TMS-MRI",Hsin-Ju Lee, K.J. Woudsma, Mohammed F. Ishraq, Fa-Hsuan Lin, Brain Stimulation (2023), DOI:10.1016/j.brs.2023.06.001.

A. The design of the TMS coil holder for TMS-MRI experiments. B. The experimental setup of TMS-MRI with an MRI-compatible TMS coil, 8-channel MRI coil array, and coil holder. IPR: In-plane rotation joint. ODR: Omni-directional rotation joint. C. Three ways to place the TMS and MRI coils at the same locations and positions, illustrating the degree of freedom offered by the holder. D. An exemplary setup of two holders at the MRI. The empty Holder 2 can mount a TMS coil, MRI coil, supporting pad, or mirror.

Publications

• US Provisional Patent No. 63/459,799
• "Design of coil holder for the improved maneuvering in concurrent TMS-MRI",Hsin-Ju Lee, K.J. Woudsma, Mohammed F. Ishraq, Fa-Hsuan Lin, Brain Stimulation (2023), DOI:10.1016/j.brs.2023.06.001

coil_holder_01s.mov

coil_holder_02s.mov

Documents

• Holder CAD file (STL format)
• Holder CAD file (eprt format)

FIG. 1

A first perspective view of an example implementation of a multi-axis lockable positioning system.

FIG. 2

A second perspective view of an example implementation of a multi-axis lockable positioning system.

FIG. 3

A third perspective view of an example implementation of a multi-axis lockable positioning system.

FIG. 4

A first cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane passing through an axis of a distal member that supports the distal functional component.

FIG. 5

A second cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that includes the rotation axis of the intermediate uniaxial locking joint and also passes through the locking mechanism.

FIG. 6

A seventh cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that passes through a central portion of the intermediate uniaxial locking joint.

FIG. 7

A third cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that includes a central axis of symmetry within the proximal arm, and also includes passes through the intermediate uniaxial locking joint and the locking mechanism.

FIG. 8

A fourth cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane passing perpendicular to the central axis of the distal member at a first location along this central axis.

FIG. 9

A fifth cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that passes perpendicular to the rotation axis of the intermediate uniaxial locking joint and also includes a central axis of the proximal member.

FIG. 10

A sixth cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that passes perpendicular to the rotation axis of the intermediate uniaxial locking joint and also lies parallel to a central axis of the proximal member.

FIG. 11

An eighth cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that includes a central axis of the intermediate arm.

FIG. 12

A ninth cutaway view of an example implementation of a multi-axis lockable positioning system, with a cut plane that lies parallel to a central axis of the intermediate arm.

FIG. 13

A perspective view of an example implementation of a multi-axis lockable positioning system, showing both the external actuator of the locking mechanism and the distal functional component.