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Slingshot in Python

This is a Python implementation of the Slingshot pseudotime algorithm (Street et al., 2018). The original implementation is written in R: https://github.com/kstreet13/slingshot.

A complete working example is located in slingshot.ipynb, using a synthetically generated dataset.

Installation:

  • Requires numpy, scipy, sklearn

  • My fork of pcurvepy (https://github.com/mossjacob/pcurvepy):

    • pip install git+https://github.com/mossjacob/pcurvepy
  • Finally install pyslingshot:

    • pip install pyslingshot

[1] Street, K., Risso, D., Fletcher, R.B., Das, D., Ngai, J., Yosef, N., Purdom, E. and Dudoit, S., 2018. Slingshot: cell lineage and pseudotime inference for single-cell transcriptomics. BMC genomics, 19(1), pp.1-16.