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Generalized Linear Model (GLM) point process model for spike trains - matlab code by J Pillow
danstowell/code_GLM
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README_glm.txt J Pillow Feb 1, 2010 (version 1) DESCRIPTION OF THE CODE CONTAINED IN THE ARCHIVE: code_glm_v1.tgz Performs simulation and maximum-likelihood fitting for several versions of a generalized linear point process model (GLM) for neural spike train data. INSTALLATION ============ (1) Unnpack the archive using a compression utility such as WinZip (or, from the command line in linux: 'tar -xvzf FILENAME.tgz'). (2) Launch matlab and cd into the main directory containing the code (e.g. '/code_GLM/'). (3) CD to the sub-directory 'tools_mexcode/' and run the initialization script 'initialize_mexcode' from the command line. This will compile the C files in the sub-directory 'mexcode' using the default compiler settings USE === (1) From the main code directory, run "setpaths" to add relevant sub-directories to the matlab path and initialize the global variable ("RefreshRate"). (2) Examine scripts in sub-directory "testscripts/" to see simple examples of simulation and fitting to spike data using the code: Test Scripts: ------------- 1. testscript_GLM.m - fits plain GLM (temporal stimulus kernel only). 2. testscript_GLM_coupled.m - fits GLM with two coupled neurons.m 3. testscript_GLM_spatialStim.m - fits GLM using two different parametrizations of stimulus kernel (linear vs. bilinear) 4. testscript_GLM_splineNlin.m - fits GLM incorporating an arbitrary nonlinearity parametrized by cubic splines. - uses coordinate ascent of filter and nonlinearity params (not concave!) - illustrates code for plotting spike rasters NOTES ===== - time is represented in units of "stimulus frames", which is controlled by the global variable RefreshRate (Hz). Thus, for example, if RefreshRate=100, each unit of time is 10ms, and a post-spike kernel discretized in time bins of width dt=.02 has time bins of length 0.2 ms. - fitting code relies on the matlab optimization toolbox ("fminunc", "fmincon"). - this code is published under the GNU General Public License. You may freely redistribute it and/or modify it under the terms of the GNU General Public License (GPLv3), available at http://www.opensource.org/licenses/gpl-3.0.html
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