In this app, you can prioritize transcription factors (TFs) and pathways based on time concordance from TG-GATEs in vivo liver data for any histopathological finding or combination thereof. Also it is possible to explore in further detail in which compound-dose combinations time concordance is observed and at which times the events are activated.
🚧 Currently deployed at: https://anikaliu.shinyapps.io/dili_cascades
Deriving time-concordant event cascades from gene expression data: A case study for Drug-Induced Liver Injury (DILI)
Anika Liu, Namshik Han, Jordi Munoz-Muriedas, Andreas Bender