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user_scenarios
The aim of this document and its subdocuments is to outline realistic scenarios for users of VFB, to assess the extent to which the site lets them achieve their aims, and to suggest improvements wherever VFB falls short.
This page is intended to briefly outline the questions users want answers to, given a specified starting point. Each starting point should link to an assesment page detailing how users can answer the listed questions using VFB, or what development would be needed to ensure that they can.
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Starting point: An image of a neuron expressing some specified transgene (e.g. obtained by a user from their own experiment.)
- Is anything known about this neuron?
- Find images and descriptions of neurons based on the brain region(s) it overlaps - do any match?
- From the literature
- From bulk datasets of single neuron images.
- Find image and descriptions of neurons known to express the specified transgene - do any match?
- Find images and descriptions of lineage clones based on its location - do any look like they include the neuron?
- Find images and descriptions of expression patterns that overlaps the same brain region(s) as these neuron - do any look like they include the neuron?
- Is anything known about this neuron?
- Find images and descriptions of neurons based on the brain region(s) it overlaps - do any match?
- From the literature
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Starting point: An identified, published neuron class:
- I have a neuron name from a paper, how can I find if VFB has a record for this?
- Show me images
- What transgenes does it express/can I use to drive expression in it?
- What neurotransmitter/neuro-peptides does it release?
- Find known or potential circuit partners
- Find publication that mention this neuron class (or its subclasses)
- I have a neuron name from a paper, how can I find if VFB has a record for this?
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Starting point: A brain region:
- Show me an image of the region
- Find publications that mention this brain region or its parts
- What neurons innervate this region?
- Known from the literature - presynaptic terminals - postsynaptic terminals
- Candidates from bulk datasets
- What tracts are connected to it?
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Starting point: 2 specified brain regions:
- What neurons connect these two brain regions?
- What tracts connect these two regions
- And what neurons fasciculated with these tracts.
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Starting point: A tract or nerve
- What does it innervate?
- What neurons fasciculate with it?
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Starting point: A transgene.
- Show me an image
- in 2D
- in 3D
- That I can compare directly to other images of expression/neurons/clones
- What neurons/brain regions express this transgene?.
- What phenotypes is it associated with?
- Show me an image
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Starting point: A publication
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Show me information about all the neurons mentioned in this paper - from whatever source.
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Show me information about all the transgenes mentioned in this paper - from whatever source.
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