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eBayes fails on dataset #1291

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ppavlidis opened this issue Nov 14, 2024 · 0 comments
Open

eBayes fails on dataset #1291

ppavlidis opened this issue Nov 14, 2024 · 0 comments
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@ppavlidis
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GSE272296

This dataset yields a prior dof that is infinite. It's a lower-quality data set (low effective library sizes), but I'm not sure why the algorithm is failing, investigation needed.

I'm considering this a bug for now, assuming we can make the algorithm work with this dataset. This should never fail or have a fallback to vanilla linear modelling. That can be done manually when running the DEA (-noBayes) but that's not a stable solution.

@ppavlidis ppavlidis added the bug label Nov 14, 2024
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