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Merge pull request #5 from OpenSourceBrain/development
Tests on mac and mac14 too, mainly to check EDEN behaviour
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<?xml version="1.0" encoding="ISO-8859-1"?> | ||
<neuroml xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.github.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd" id="Ca_conc"> | ||
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<notes>NeuroML file describing intracellular Calcium dynamics, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<fixedFactorConcentrationModel id="Ca_conc" restingConc="0.0mM" decayConstant="0.1s" ion="ca" rho="9543.150099999999mol_per_m_per_A_per_s"/> | ||
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</neuroml> |
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@@ -1,70 +1,106 @@ | ||
<?xml version="1.0" encoding="ISO-8859-1"?> | ||
<neuroml xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.github.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd" id="Ca_pyr"> | ||
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<notes>NeuroML file containing a single Calcium Channel description, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<ionChannel id="Ca_pyr" conductance="10pS" type="ionChannelHH" species="ca"> | ||
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<notes>NeuroML file containing a single Calcium Channel description, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<notes>NeuroML file containing a single Calcium Channel description, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<annotation> | ||
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"> | ||
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<rdf:Description rdf:about="Ca_pyr"> | ||
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<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> | ||
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<rdf:Bag> | ||
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<rdf:li>Traub, R. D., Wong, R. K., Miles, R., and Michelson, H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of neurophysiology, 66(2), 635-50.</rdf:li> | ||
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<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/1663538"/> | ||
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</rdf:Bag> | ||
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</bqmodel:isDescribedBy> | ||
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<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/"> | ||
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<rdf:Bag> | ||
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<rdf:li>Ca channels</rdf:li> | ||
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<rdf:li rdf:resource="http://senselab.med.yale.edu/neurondb/NeuronProp.aspx?id=259&mo=1&re=&pr=C"/> | ||
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</rdf:Bag> | ||
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</bqbiol:isVersionOf> | ||
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</rdf:Description> | ||
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</rdf:RDF> | ||
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</annotation> | ||
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<gate id="m" type="gateHHrates" instances="2"> | ||
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<forwardRate type="HHSigmoidRate" rate="1.6e3per_s" scale="0.01389V" midpoint="5e-03V"/> | ||
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<reverseRate type="HHExpLinearRate" rate="1e2per_s" scale="-0.005V" midpoint="-8.9e-3V"/> | ||
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</gate> | ||
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<gate id="h" type="gateHHtauInf" instances="1"> | ||
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<timeCourse type="Ca_pyr_h_tau_tau"/> | ||
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<steadyState type="Ca_pyr_h_inf_inf"/> | ||
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</gate> | ||
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</ionChannel> | ||
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<ComponentType name="Ca_pyr_h_tau_tau" extends="baseVoltageDepTime"> | ||
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<Constant name="TIME_SCALE" dimension="time" value="1 s"/> | ||
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<Constant name="VOLT_SCALE" dimension="voltage" value="1 V"/> | ||
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<Dynamics> | ||
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<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/> | ||
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<DerivedVariable name="t" exposure="t" dimension="time" value="(0.2) * TIME_SCALE"/> | ||
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</Dynamics> | ||
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</ComponentType> | ||
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<ComponentType name="Ca_pyr_h_inf_inf" extends="baseVoltageDepVariable"> | ||
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<Constant name="TIME_SCALE" dimension="time" value="1 s"/> | ||
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<Constant name="VOLT_SCALE" dimension="voltage" value="1 V"/> | ||
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<Dynamics> | ||
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<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/> | ||
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<ConditionalDerivedVariable name="x" exposure="x" dimension="none"> | ||
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<Case condition="V .gt. ( -0.06 )" value=" (exp (-50*(V + 0.06))) "/> | ||
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<Case value=" 1"/> | ||
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</ConditionalDerivedVariable> | ||
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</Dynamics> | ||
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</ComponentType> | ||
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</neuroml> |
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<?xml version="1.0" encoding="ISO-8859-1"?> | ||
<neuroml xmlns="http://www.neuroml.org/schema/neuroml2" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.github.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd" id="Kahp_pyr"> | ||
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<notes>NeuroML file containing a single Calcium-dependent Potassium Channel description, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<ionChannel id="Kahp_pyr" conductance="10pS" type="ionChannelHH" species="k"> | ||
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<notes>NeuroML file containing a single Calcium-dependent Potassium Channel description, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<notes>NeuroML file containing a single Calcium-dependent Potassium Channel description, from the Hippocampal CA3 neuron model presented in Traub et al., 1991.</notes> | ||
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<annotation> | ||
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<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"> | ||
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<rdf:Description rdf:about="Kahp_pyr"> | ||
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<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/"> | ||
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<rdf:Bag> | ||
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<rdf:li>Traub, R. D., Wong, R. K., Miles, R., and Michelson, H. (1991). A model of a CA3 hippocampal pyramidal neuron incorporating voltage-clamp data on intrinsic conductances. Journal of neurophysiology, 66(2), 635-50.</rdf:li> | ||
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<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/1663538"/> | ||
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</rdf:Bag> | ||
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</bqmodel:isDescribedBy> | ||
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<bqbiol:isVersionOf xmlns:bqbiol="http://biomodels.net/biology-qualifiers/"> | ||
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<rdf:Bag> | ||
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<rdf:li>K channels</rdf:li> | ||
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<rdf:li rdf:resource="http://senselab.med.yale.edu/neurondb/NeuronProp.aspx?id=259&mo=1&re=&pr=C"/> | ||
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</rdf:Bag> | ||
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</bqbiol:isVersionOf> | ||
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</rdf:Description> | ||
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</rdf:RDF> | ||
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</annotation> | ||
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<gate id="z" type="gateHHrates" instances="1"> | ||
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<forwardRate type="Kahp_pyr_z_alpha_rate"/> | ||
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<reverseRate type="Kahp_pyr_z_beta_rate"/> | ||
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</gate> | ||
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</ionChannel> | ||
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<ComponentType name="Kahp_pyr_z_alpha_rate" extends="baseVoltageConcDepRate"> | ||
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<Constant name="TIME_SCALE" dimension="time" value="1 s"/> | ||
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<Constant name="VOLT_SCALE" dimension="voltage" value="1 V"/> | ||
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<Constant name="CONC_SCALE" dimension="concentration" value="1 mM"/> | ||
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<Dynamics> | ||
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<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/> | ||
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<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/> | ||
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<ConditionalDerivedVariable name="r" exposure="r" dimension="per_time"> | ||
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<Case condition="ca_conc .lt. ( 500.0 )" value="( 0.4 * ca_conc ) / TIME_SCALE"/> | ||
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<Case value="( 200) / TIME_SCALE"/> | ||
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</ConditionalDerivedVariable> | ||
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</Dynamics> | ||
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</ComponentType> | ||
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<ComponentType name="Kahp_pyr_z_beta_rate" extends="baseVoltageConcDepRate"> | ||
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<Constant name="TIME_SCALE" dimension="time" value="1 s"/> | ||
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<Constant name="VOLT_SCALE" dimension="voltage" value="1 V"/> | ||
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<Constant name="CONC_SCALE" dimension="concentration" value="1 mM"/> | ||
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<Dynamics> | ||
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<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/> | ||
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<DerivedVariable name="ca_conc" dimension="none" value="caConc / CONC_SCALE"/> | ||
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<DerivedVariable name="r" exposure="r" dimension="per_time" value="(20) / TIME_SCALE"/> | ||
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</Dynamics> | ||
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</ComponentType> | ||
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</neuroml> |
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