Fixes #1929 hill transporter issue (#1941)

* Fixes #1929 hill transporter issue * Using the right project
Open-Systems-Pharmacology · Nov 3, 2021 · 30d820c · 30d820c
1 parent 31a3db1
commit 30d820c
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Showing 5 changed files with 37 additions and 5 deletions.
diff --git a/src/Db/Diff/PKSimDB_diff.txt b/src/Db/Diff/PKSimDB_diff.txt
@@ -1,2 +1,2 @@
-UPDATE tab_populations SET display_name='Japanese (Schlender, 2015)', description='Japanese (Schlender, 2015)' WHERE population='Japanese_Population';
-UPDATE tab_populations SET display_name='Preterm (Claassen, 2015)', description='Preterm (Claassen, 2015)' WHERE population='Preterm';
+INSERT INTO tab_rate_generic_parameters(calculation_method,formula_rate,path_id,parameter_name,alias) VALUES('LinksCommon','MucosaActiveInfluxFromLumen_Hill',2690,'Effective concentration in lumen','EffectiveLumenConcentration');
+DELETE FROM tab_rate_generic_parameters WHERE calculation_method='LinksCommon' AND formula_rate='MucosaActiveInfluxFromLumen_Hill' AND path_id=2704 AND parameter_name='Effective concentration in lumen';
diff --git a/src/Db/Dump/PKSimDB_dump.txt b/src/Db/Dump/PKSimDB_dump.txt
@@ -88234,7 +88234,7 @@ INSERT INTO tab_rate_generic_parameters VALUES('Lumen_PKSim','PARAM_EffectiveLum
 INSERT INTO tab_rate_generic_parameters VALUES('Lumen_PKSim','PARAM_EffectiveLumenConcentration',139,'Solubility','Solubility');
 INSERT INTO tab_rate_generic_parameters VALUES('Lumen_PKSim','PARAM_EffectiveLumenConcentration',140,'Liquid','Liquid');
 INSERT INTO tab_rate_generic_parameters VALUES('Lumen_PKSim','PARAM_EffectiveLumenConcentration',240,'Molecular weight','MW');
-INSERT INTO tab_rate_generic_parameters VALUES('LinksCommon','MucosaActiveInfluxFromLumen_Hill',2704,'Effective concentration in lumen','EffectiveLumenConcentration');
+INSERT INTO tab_rate_generic_parameters VALUES('LinksCommon','MucosaActiveInfluxFromLumen_Hill',2690,'Effective concentration in lumen','EffectiveLumenConcentration');
 INSERT INTO tab_rate_generic_parameters VALUES('LinksCommon','MucosaActiveInfluxFromLumen_MM',2690,'Effective concentration in lumen','EffectiveLumenConcentration');
 INSERT INTO tab_rate_generic_parameters VALUES('LinksCommon','MucosaPgPToLumen_Hill',2704,'Effective concentration in lumen','EffectiveLumenConcentration');
 INSERT INTO tab_rate_generic_parameters VALUES('LinksCommon','MucosaPgPToLumen_MM',2704,'Effective concentration in lumen','EffectiveLumenConcentration');

diff --git a/src/Db/PKSimDB.sqlite b/src/Db/PKSimDB.sqlite
diff --git a/tests/PKSim.Tests/Data/MucosaInflux_Hill.pksim5 b/tests/PKSim.Tests/Data/MucosaInflux_Hill.pksim5
diff --git a/tests/PKSim.Tests/IntegrationTests/ProcessToProcessBuilderMapperSpecs.cs b/tests/PKSim.Tests/IntegrationTests/ProcessToProcessBuilderMapperSpecs.cs
@@ -8,7 +8,7 @@
 
 namespace PKSim.IntegrationTests
 {
-   public abstract class concern_for_ProcessToProcessBuilderMapper : ContextWithLoadedProject<IProcessToProcessBuilderMapper>
+   public abstract class concern_for_Mucosa_MultipleTransportDirections : ContextWithLoadedProject<IProcessToProcessBuilderMapper>
    {
       public override void GlobalContext()
       {
@@ -17,7 +17,7 @@ public override void GlobalContext()
       }
    }
 
-   public class When_creating_a_simulation_using_transport_in_multiple_mucosa_directions : concern_for_ProcessToProcessBuilderMapper
+   public class When_creating_a_simulation_using_transport_in_multiple_mucosa_directions : concern_for_Mucosa_MultipleTransportDirections
    {
       private Simulation _simulation;
 
@@ -37,4 +37,36 @@ public void should_not_create_too_many_transporters()
          transportInLumenToMucosa.GetChildren<IContainer>(x => x.ContainerType == ContainerType.Transport).Count().ShouldBeEqualTo(1);
       }
    }
+
+   public abstract class concern_for_MucosaInflux_Hill : ContextWithLoadedProject<IProcessToProcessBuilderMapper>
+   {
+      public override void GlobalContext()
+      {
+         base.GlobalContext();
+         LoadProject("MucosaInflux_Hill");
+      }
+   }
+
+   public class When_creating_a_simulation_using_mucosa_influx_hill_kinetic : concern_for_MucosaInflux_Hill
+   {
+      private Simulation _simulation;
+
+      protected override void Context()
+      {
+         base.Context();
+         var ind = FindByName<Individual>("I1");
+         var comp = FindByName<Compound>("C1");
+         var prot = FindByName<Protocol>("IV");
+         _simulation = DomainFactoryForSpecs.CreateSimulationWith(ind, comp, prot);
+
+      }
+
+      [Observation]
+      public void should_be_able_to_create_a_simulation()
+      {
+         _simulation.ShouldNotBeNull();
+      }
+   }
+
+
 }