Skip to content

Commit

Permalink
Fix table links
Browse files Browse the repository at this point in the history
  • Loading branch information
PavelBal committed Mar 25, 2022
1 parent a761edc commit 6ad67a5
Showing 1 changed file with 4 additions and 4 deletions.
8 changes: 4 additions & 4 deletions Evaluation/Input/Content/Section2.2_Data.md
Original file line number Diff line number Diff line change
@@ -1,6 +1,6 @@
### 2.2.1 In vitro and physico-chemical data

A literature search was performed to collect available information on physico-chemical properties of ethinylestradiol, see [Table 1](#Table 1).
A literature search was performed to collect available information on physico-chemical properties of ethinylestradiol, see [Table 1](#table-1).

| **Parameter** | **Unit** | **Value** | Source | **Description** |
| :------------------------------ | ----------------- | ---------------- | --------------------------------- | ---------------------------------------------- |
Expand All @@ -19,11 +19,11 @@ A literature search was performed to collect available information on physico-ch
| Clint HLM<sup>+</sup> | µL/min/mg prot. | 118.83 | [Ezuruike 2018](#5-references) | Intrinsic clearance in Human Liver Microsomes |
| Ki CYP1A2 | µmol/l | 10.6 | [Karjalainen 2008](#5-references) | CYP1A2 inhibition constant |

**Table 1:**<a name="Table 1"></a> Physico-chemical and *in-vitro* metabolization properties of ethinylestradiol extracted from literature. *<sup>+</sup>: Value used in final model*
**Table 1:**<a name="table-1"></a> Physico-chemical and *in-vitro* metabolization properties of ethinylestradiol extracted from literature. *<sup>+</sup>: Value used in final model*

### 2.2.2 Clinical data

A literature search was performed to collect available clinical data on ethinylestradiol, see [Table 2](#Table 2).
A literature search was performed to collect available clinical data on ethinylestradiol, see [Table 2](#table-2).

| **Source** | Route | **Dose [mg]/** **Schedule \*** | **Pop.** | **Sex** | **N** | **Form.** |
| -------------------- | ------------------------------- | ------------ | ------- | --------------------------------- | --------------------------------- | --------------------------------- |
Expand All @@ -44,4 +44,4 @@ A literature search was performed to collect available clinical data on ethinyle
| [Kothare 2012](#5-references)<sup>+</sup> | p.o. | 0.03/0.03 q.d. | HV | F | 20 | tablet |
| [Timmer 2000](#5-references)<sup>+</sup> | p.o. | 0.03 | HV | F | - | tablet |

**Table 2:**<a name="Table 2"></a> Literature sources of clinical concentration data of ethinylestradiol used for model development and validation. *\*: single dose unless otherwise specified;<sup>+</sup>: Data used for final parameter identification*
**Table 2:**<a name="table-2"></a> Literature sources of clinical concentration data of ethinylestradiol used for model development and validation. *\*: single dose unless otherwise specified;<sup>+</sup>: Data used for final parameter identification*

0 comments on commit 6ad67a5

Please sign in to comment.