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MEC layer II stellate cell: Synaptic mechanisms of grid cells (Schmidt-Hieber & Hausser 2013)

modeldb.science/150239

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demo		demo
nrn		nrn
README.html		README.html
mosinit.hoc		mosinit.hoc
screenshot.png		screenshot.png

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This code accompanies the publication:

Schmidt-Hieber C, Hausser M (2013)
Cellular mechanisms of spatial navigation in the medial entorhinal
cortex.
Nat Neurosci 16:325--331

Send comments to c.schmidt-hieber_at_ucl.ac.uk

Currently, only the compartmental stellate cell model [1] is included.
I will add the oi and can model implementations at a later time.

INSTALLATION

Install NEURON, ideally with Python support:
http://www.neuron.yale.edu

USAGE

1. Compile the mechanism files in the mod directory:
   $ nrnivmodl nrn/mod

2. Run the demo:
   $ ./x86_64/special demo/test_rin.hoc -

   or

   $ python demo/test_rin.py

The demo runs with 11 injected current pulses from -0.05 to .45 nA in
steps of 0.05.  When the demo is finished (takes a few seconds) you
should have a graph that looks like this:

<img src="./screenshot.png" alt="screenshot">

[1] Morphology based on:
D. L. Garden, P. D. Dodson, C. O'Donnell, M. D. White, M. F. Nolan
Tuning of synaptic integration in the medial entorhinal cortex to the
organization of grid cell firing fields.
Neuron 60, 875 (2008).
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