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ImmuCellAI 2.0 is an advanced bulk transcriptome deconvolution tool that accurately infers the proportions of a comprehensive range of immune cell types, including rare subsets, from bulk RNA-seq data.

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ImmuCellAI 2.0

ImmuCellAI 2.0 is an advanced bulk transcriptome deconvolution tool that accurately infers the proportions of a comprehensive range of immune cell types, including rare subsets, from bulk RNA-seq data.

ImmuCellAI 2.0 Website

The ImmuCellAI 2.0 Website is a valuable online resource for immunology research, supporting the estimation of immune cell abundance across 9 major immune cell types and their corresponding 53 minor subtypes. Access it here: https://guolab.wchscu.cn/immucellai/

Install ImmuCellAI 2.0

Install using pip

pip install immucellai2

Usage

ImmuCellAI 2.0 expects a TPM matrix as input and can be implemented with only two lines of code in Python.

import immucellai2
reference_data = immucellai2.load_tumor_reference_data()
result = immucellai2.run_ImmuCellAI2(
    reference_file=reference_data,
    sample_file=<file_path>,    #  User-defined
    output_file=<file_path>,    #  User-defined
    thread_num=8
)

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ImmuCellAI 2.0 is an advanced bulk transcriptome deconvolution tool that accurately infers the proportions of a comprehensive range of immune cell types, including rare subsets, from bulk RNA-seq data.

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