multiomics_integration

Using miRNA, proteomics and metabolomics data and their integration to study disease subclassification and insights in PSC patients.

1. These scripts reads the data (csv files) and pre-processes it in preparation for analysis and integration:

metadata_preprocessing.R
miRNA_preprocessing.R
protein_preprocessing.R
metadata_preprocessing.R

2. These scripts analyse the data

data_exploration.Rmd
WGCNA_multi_omics.Rmd
mixOmics_multi_omics.Rmd
enrichment_analysis.Rmd

3. Extra scripts

WGCNA_conc.Rmd (older version of WGCNA_multi_omics.Rmd) WGCNA_uniomic.Rmd (using WGCNA on each omic data without concatenation or integration)