WIP: Fix bug issue 190: Add new test ... also WIP. Update BCK and dfB…

…DG to address study with unpaired readers.

Rpackage/iMRMC/R/doAUCMRMC.R

@@ -825,9 +825,11 @@ doAUCmrmcCov <- function(perReaderPair.1) {
   ####
   #### Biased moments
   #### 
-  m.biased <- numer / denom
-
+  index.TF <- denom != 0
+  m.biased <- numer
+  m.biased[index.TF] <- m.biased[index.TF] / denom[index.TF]
 
+
 
   ####
   #### Transformation: map biased sums to unbiased sums
@@ -856,7 +858,9 @@ doAUCmrmcCov <- function(perReaderPair.1) {
   ####
   #### Unbiased moments
   #### 
-  m <- numer.U / denom.U
+  index.TF <- denom.U != 0
+  m <- numer.U
+  m[index.TF] <- m[index.TF] / denom.U[index.TF]
 
 
 
@@ -951,6 +955,14 @@ doAUCmrmcCov <- function(perReaderPair.1) {
                         "BCK.NR.coeff", "BCK.DR.coeff", "BCK.RND.coeff")
 
 
+
+  # Manage studies that do not pair readers or cases across modalities
+  index <- BCK.coeff[1, ] == 0
+  BCK[1, index] <- 0
+  BCK.biased[1, index] <- 0
+
+
+
   ####
   #### Degrees of freedom
   #### 

Rpackage/iMRMC/R/iMRMC_R.R

@@ -172,23 +172,27 @@ origPerReader <- function(result_AUC_MRMC) {
 
   # When the modalities are different, fill them appropriately
   index.TF <- current$modalityA != current$modalityB
-  current.12 <- current[index.TF, ]
-  if (nM > 1) {
-    for (i in 1:sum(index.TF)) {
-      current.i <- current[
-        (current$readerID == current.12$readerID[i]) &
-          (current$modalityA == current.12$modalityA[i]) &
-          (current$modalityB == current.12$modalityA[i]), 
-      ]
-      current.12$varAUCA[i] <- current.i$varAUCA
-      current.i <- current[
-        (current$readerID == current.12$readerID[i]) &
-          (current$modalityA == current.12$modalityB[i]) &
-          (current$modalityB == current.12$modalityB[i]), 
-      ]
-      current.12$varAUCB[i] <- current.i$varAUCB
+  if (sum(index.TF) > 0) {
+
+    current.12 <- current[index.TF, ]
+    if (nM > 1) {
+      for (i in 1:sum(index.TF)) {
+        current.i <- current[
+          (current$readerID == current.12$readerID[i]) &
+            (current$modalityA == current.12$modalityA[i]) &
+            (current$modalityB == current.12$modalityA[i]), 
+        ]
+        current.12$varAUCA[i] <- current.i$varAUCA
+        current.i <- current[
+          (current$readerID == current.12$readerID[i]) &
+            (current$modalityA == current.12$modalityB[i]) &
+            (current$modalityB == current.12$modalityB[i]), 
+        ]
+        current.12$varAUCB[i] <- current.i$varAUCB
+      }
+      current[index.TF, c("varAUCA", "varAUCB")] <- current.12[, c("varAUCA", "varAUCB")]
     }
-    current[index.TF, c("varAUCA", "varAUCB")] <- current.12[, c("varAUCA", "varAUCB")]
+
   }
 
   # Add columns for AUCAminusAUCB and varAUCAminusAUCB