diff --git a/packages/@uppy/core/src/Uppy.test.ts b/packages/@uppy/core/src/Uppy.test.ts
index e279dbdd3c..c4ee610427 100644
--- a/packages/@uppy/core/src/Uppy.test.ts
+++ b/packages/@uppy/core/src/Uppy.test.ts
@@ -7,8 +7,10 @@ import assert from 'node:assert'
 import fs from 'node:fs'
 import path from 'node:path'
 import prettierBytes from '@transloadit/prettier-bytes'
+import type { Body, Meta } from '@uppy/utils/lib/UppyFile'
 import Core from './index.ts'
 import UIPlugin from './UIPlugin.ts'
+import BasePlugin, { type PluginOpts } from './BasePlugin.ts'
 import { debugLogger } from './loggers.ts'
 import AcquirerPlugin1 from './mocks/acquirerPlugin1.ts'
 import AcquirerPlugin2 from './mocks/acquirerPlugin2.ts'
@@ -61,6 +63,33 @@ describe('src/Core', () => {
       ).toEqual(1)
     })
 
+    it('should be able to .use() without passing generics again', () => {
+      interface TestOpts extends PluginOpts {
+        foo?: string
+        bar: string
+      }
+      class TestPlugin<M extends Meta, B extends Body> extends BasePlugin<
+        TestOpts,
+        M,
+        B
+      > {
+        foo: string
+
+        constructor(uppy: Core<M, B>, opts: TestOpts) {
+          super(uppy, opts)
+          this.id = 'Test'
+          this.type = 'acquirer'
+          this.foo = opts?.foo ?? 'bar'
+        }
+      }
+      new Core().use(TestPlugin)
+      new Core().use(TestPlugin, { foo: '', bar: '' })
+      // @ts-expect-error boolean not allowed
+      new Core().use(TestPlugin, { foo: false })
+      // @ts-expect-error missing option
+      new Core().use(TestPlugin, { foo: '' })
+    })
+
     it('should prevent the same plugin from being added more than once', () => {
       const core = new Core()
       core.use(AcquirerPlugin1)
diff --git a/packages/@uppy/core/src/Uppy.ts b/packages/@uppy/core/src/Uppy.ts
index 8ab01aa003..368416f016 100644
--- a/packages/@uppy/core/src/Uppy.ts
+++ b/packages/@uppy/core/src/Uppy.ts
@@ -39,7 +39,6 @@ import locale from './locale.ts'
 import type BasePlugin from './BasePlugin.ts'
 import type UIPlugin from './UIPlugin.ts'
 import type { Restrictions } from './Restricter.ts'
-import type { PluginOpts } from './BasePlugin.ts'
 
 type Processor = (fileIDs: string[], uploadID: string) => Promise<void> | void
 
@@ -1663,9 +1662,9 @@ export class Uppy<M extends Meta, B extends Body> {
   /**
    * Registers a plugin with Core.
    */
-  use<O extends PluginOpts, I extends UIPlugin<O, M, B> | BasePlugin<O, M, B>>(
-    Plugin: new (uppy: this, opts?: O) => I,
-    opts?: O,
+  use<T extends typeof BasePlugin<any, M, B> | typeof UIPlugin<any, M, B>>(
+    Plugin: T,
+    opts?: ConstructorParameters<T>[1],
   ): this {
     if (typeof Plugin !== 'function') {
       const msg =