diff --git a/packages/jest-runner/src/jest-plugins/with-coverage-analysis.ts b/packages/jest-runner/src/jest-plugins/with-coverage-analysis.ts
index 22b45be647..798aa115c9 100644
--- a/packages/jest-runner/src/jest-plugins/with-coverage-analysis.ts
+++ b/packages/jest-runner/src/jest-plugins/with-coverage-analysis.ts
@@ -18,7 +18,7 @@ const jestEnvironmentGenericFileName = fileURLToPath(new URL('./jest-environment
  */
 function getJestDefaults(jestWrapper: JestWrapper) {
   // New defaults since 27: https://jestjs.io/blog/2021/05/25/jest-27
-  if (semver.satisfies(jestWrapper.getVersion(), '>=27')) {
+  if (semver.satisfies(semver.coerce(jestWrapper.getVersion())!, '>=27')) {
     return {
       testRunner: 'jest-circus/runner',
       testEnvironment: 'node',
diff --git a/packages/jest-runner/src/jest-test-adapters/jest-test-adapter-factory.ts b/packages/jest-runner/src/jest-test-adapters/jest-test-adapter-factory.ts
index 5724298aa1..da1c1fd38d 100644
--- a/packages/jest-runner/src/jest-test-adapters/jest-test-adapter-factory.ts
+++ b/packages/jest-runner/src/jest-test-adapters/jest-test-adapter-factory.ts
@@ -1,13 +1,21 @@
 import { Logger } from '@stryker-mutator/api/logging';
 import { StrykerOptions } from '@stryker-mutator/api/core';
 import { commonTokens, Injector, tokens } from '@stryker-mutator/api/plugin';
-import semver from 'semver';
+import semver, { SemVer } from 'semver';
 
 import { JestPluginContext, pluginTokens } from '../plugin-di.js';
 import { JestWrapper } from '../utils/jest-wrapper.js';
 
 import { JestLessThan25TestAdapter } from './jest-less-than-25-adapter.js';
 import { JestGreaterThan25TestAdapter } from './jest-greater-than-25-adapter.js';
+interface CoercedVersion {
+  version: SemVer;
+  raw: string;
+}
+
+function coerceVersion(version: string): CoercedVersion {
+  return { version: semver.coerce(version)!, raw: version };
+}
 
 export function jestTestAdapterFactory(
   log: Logger,
@@ -15,11 +23,11 @@ export function jestTestAdapterFactory(
   options: StrykerOptions,
   injector: Injector<JestPluginContext>,
 ): JestGreaterThan25TestAdapter | JestLessThan25TestAdapter {
-  const version = jestWrapper.getVersion();
-  log.debug('Detected Jest version %s', version);
-  guardJestVersion(version, options, log);
+  const coercedVersion = coerceVersion(jestWrapper.getVersion());
+  log.debug('Detected Jest version %s', coercedVersion.raw);
+  guardJestVersion(coercedVersion, options, log);
 
-  if (semver.satisfies(version, '<25.0.0')) {
+  if (semver.satisfies(coercedVersion.version, '<25.0.0')) {
     return injector.injectClass(JestLessThan25TestAdapter);
   } else {
     return injector.injectClass(JestGreaterThan25TestAdapter);
@@ -27,10 +35,10 @@ export function jestTestAdapterFactory(
 }
 jestTestAdapterFactory.inject = tokens(commonTokens.logger, pluginTokens.jestWrapper, commonTokens.options, commonTokens.injector);
 
-function guardJestVersion(jest: string, options: StrykerOptions, log: Logger) {
-  if (semver.satisfies(jest, '<22.0.0')) {
-    throw new Error(`You need Jest version >= 22.0.0 to use the @stryker-mutator/jest-runner plugin, found ${jest}`);
-  } else if (semver.satisfies(jest, '<24')) {
+function guardJestVersion({ version, raw }: CoercedVersion, options: StrykerOptions, log: Logger) {
+  if (semver.satisfies(version, '<22.0.0')) {
+    throw new Error(`You need Jest version >= 22.0.0 to use the @stryker-mutator/jest-runner plugin, found ${raw}`);
+  } else if (semver.satisfies(version, '<24')) {
     if (options.coverageAnalysis !== 'off') {
       throw new Error(
         `You need Jest version >= 24.0.0 to use the @stryker-mutator/jest-runner with "coverageAnalysis": "${options.coverageAnalysis}", you're currently using version 23.0.0. Please upgrade your jest version, or set "coverageAnalysis": "off".`,
@@ -38,7 +46,7 @@ function guardJestVersion(jest: string, options: StrykerOptions, log: Logger) {
     }
     log.warn(
       '[DEPRECATED] Support for Jest version < 24 is deprecated and will be removed in the next major version of Stryker, please upgrade your jest version (your current version is %s).',
-      jest,
+      raw,
     );
   }
 }
diff --git a/packages/jest-runner/test/unit/jest-test-adapters/jest-test-adapter-factory.spec.ts b/packages/jest-runner/test/unit/jest-test-adapters/jest-test-adapter-factory.spec.ts
index 6690523532..e58e8648b6 100644
--- a/packages/jest-runner/test/unit/jest-test-adapters/jest-test-adapter-factory.spec.ts
+++ b/packages/jest-runner/test/unit/jest-test-adapters/jest-test-adapter-factory.spec.ts
@@ -37,19 +37,32 @@ describe(jestTestAdapterFactory.name, () => {
     expect(testInjector.logger.debug).calledWith('Detected Jest version %s', '25.0.0');
   });
 
-  it('should return a JestGreaterThan25Adapter when the Jest version is higher or equal to 25.0.0', () => {
+  it('should return a JestGreaterThan25Adapter when the Jest version is greater or equal to 25.0.0', () => {
     jestWrapperMock.getVersion.returns('25.0.0');
     const testAdapter = act();
 
     expect(testAdapter).instanceOf(JestGreaterThan25TestAdapter);
   });
-  it('should return a JestLessThan25Adapter when the Jest version is higher or equal to 22.0.0, but less then 25 and coverage analysis is disabled', () => {
+  it('should return a JestGreaterThan25Adapter when the Jest version is an alpha version greater than 25.0.0', () => {
+    jestWrapperMock.getVersion.returns('30.0.0-alpha.6');
+    const testAdapter = act();
+
+    expect(testAdapter).instanceOf(JestGreaterThan25TestAdapter);
+  });
+  it('should return a JestLessThan25Adapter when the Jest version is greater or equal to 22.0.0, but less then 25 and coverage analysis is disabled', () => {
     testInjector.options.coverageAnalysis = 'off';
     jestWrapperMock.getVersion.returns('22.0.0');
     const testAdapter = act();
 
     expect(testAdapter).instanceOf(JestLessThan25TestAdapter);
   });
+  it('should return a JestLessThan25Adapter when the Jest version is an alpha version greater than 22.0.0, lower than 25', () => {
+    testInjector.options.coverageAnalysis = 'off';
+    jestWrapperMock.getVersion.returns('23.0.0-alpha.6');
+    const testAdapter = act();
+
+    expect(testAdapter).instanceOf(JestLessThan25TestAdapter);
+  });
 
   it('should throw an error when the Jest version is lower than 22.0.0', () => {
     jestWrapperMock.getVersion.returns('21.0.0');
@@ -57,6 +70,12 @@ describe(jestTestAdapterFactory.name, () => {
     expect(act).to.throw(Error, 'You need Jest version >= 22.0.0 to use the @stryker-mutator/jest-runner plugin, found 21.0.0');
   });
 
+  it('should throw an error when the Jest version is an alpha version lower than 22.0.0', () => {
+    jestWrapperMock.getVersion.returns('21.0.0-alpha.6');
+
+    expect(act).to.throw(Error, 'You need Jest version >= 22.0.0 to use the @stryker-mutator/jest-runner plugin, found 21.0.0-alpha.6');
+  });
+
   it('should throw an error when the Jest version is between 22 and 24, but coverage analysis is enabled', () => {
     jestWrapperMock.getVersion.returns('23.0.0');
     testInjector.options.coverageAnalysis = 'all';
diff --git a/packages/jest-runner/test/unit/jest-test-runner.spec.ts b/packages/jest-runner/test/unit/jest-test-runner.spec.ts
index d077c11a1a..5e77a0dd65 100644
--- a/packages/jest-runner/test/unit/jest-test-runner.spec.ts
+++ b/packages/jest-runner/test/unit/jest-test-runner.spec.ts
@@ -376,7 +376,7 @@ describe(JestTestRunner.name, () => {
         });
       });
 
-      it('should not add a set setupFile if testRunner is not specified and jest version >= 27 (circus test runner)', async () => {
+      it('should not add a setupFile if testRunner is not specified and jest version >= 27 (circus test runner)', async () => {
         jestWrapperMock.getVersion.returns('27.0.0');
         options.jest.config = { testRunner: undefined };
         const sut = await arrangeInitializedSut();
@@ -386,6 +386,16 @@ describe(JestTestRunner.name, () => {
         });
       });
 
+      it('should not add a setupFile if testRunner is not specified and jest is an alpha version >= 27 (circus test runner)', async () => {
+        jestWrapperMock.getVersion.returns('30.0.0-alpha.6');
+        options.jest.config = { testRunner: undefined };
+        const sut = await arrangeInitializedSut();
+        await sut.dryRun(factory.dryRunOptions({ coverageAnalysis: 'perTest' }));
+        expect(jestTestAdapterMock.run).calledWithMatch({
+          jestConfig: sinon.match({ setupFilesAfterEnv: undefined }),
+        });
+      });
+
       it('should not allow the circus test runner for coverage analysis "perTest"', async () => {
         options.jest.config = { testRunner: 'jest-circus/runner' };
         const sut = await arrangeInitializedSut();