diff --git a/dsn.go b/dsn.go
index 85d86f1d7..557f5b897 100644
--- a/dsn.go
+++ b/dsn.go
@@ -141,11 +141,16 @@ func (c *Config) ocspMode() string {
 
 // DSN constructs a DSN for Snowflake db.
 func DSN(cfg *Config) (dsn string, err error) {
-	if cfg.Region == "us-west-2" {
+	if strings.ToLower(cfg.Region) == "us-west-2" {
 		cfg.Region = ""
 	}
 	// in case account includes region
 	region, posDot := extractRegionFromAccount(cfg.Account)
+	if strings.ToLower(region) == "us-west-2" {
+		region = ""
+		cfg.Account = cfg.Account[:posDot]
+		logger.Info("Ignoring default region .us-west-2 in DSN from Account configuration.")
+	}
 	if region != "" {
 		if cfg.Region != "" {
 			return "", errRegionConflict()
@@ -587,6 +592,11 @@ func transformAccountToHost(cfg *Config) (err error) {
 		// account name is specified instead of host:port
 		cfg.Account = cfg.Host
 		region, posDot := extractRegionFromAccount(cfg.Account)
+		if strings.ToLower(region) == "us-west-2" {
+			region = ""
+			cfg.Account = cfg.Account[:posDot]
+			logger.Info("Ignoring default region .us-west-2 from Account configuration.")
+		}
 		if region != "" {
 			cfg.Region = region
 			cfg.Account = cfg.Account[:posDot]
diff --git a/dsn_test.go b/dsn_test.go
index ec4f61303..9052b5c19 100644
--- a/dsn_test.go
+++ b/dsn_test.go
@@ -1297,6 +1297,22 @@ func TestDSN(t *testing.T) {
 			},
 			dsn: "u:p@account-name.cn-region.snowflakecomputing.cn:443?account=account-name&ocspFailOpen=true&region=cn-region&validateDefaultParameters=true",
 		},
+		{
+			cfg: &Config{
+				User:     "u",
+				Password: "p",
+				Account:  "account.us-west-2",
+			},
+			dsn: "u:p@account.snowflakecomputing.com:443?ocspFailOpen=true&validateDefaultParameters=true",
+		},
+		{
+			cfg: &Config{
+				User:     "u",
+				Password: "p",
+				Account:  "account_us-west-2",
+			},
+			dsn: "u:p@account_us-west-2.snowflakecomputing.com:443?ocspFailOpen=true&validateDefaultParameters=true",
+		},
 		{
 			cfg: &Config{
 				User:     "u",