diff --git a/CHANGES.rst b/CHANGES.rst
index 095e28f..ba905a0 100644
--- a/CHANGES.rst
+++ b/CHANGES.rst
@@ -3,6 +3,10 @@
 
 - Fixing compatibility with pytest-asyncio. [#278]
 
+- Adding new directive ``doctest-requires-all`` to conditionally skip all
+  doctests in narrative documentations based on availability of
+  dependencies. [#280]
+
 - Versions of Python <3.9 are no longer supported. [#274]
 
 1.3.0 (2024-11-25)
diff --git a/README.rst b/README.rst
index 739c22b..48b26f6 100644
--- a/README.rst
+++ b/README.rst
@@ -336,6 +336,9 @@ the package's ``setup.cfg`` file. The syntax for this option is a list of
 
 Multiple requirements can be specified if separated by semicolons.
 
+It is also possible to conditionally skip all the doctests in a narrative
+documentation with ``doctest-requires-all``.
+
 Remote Data
 ~~~~~~~~~~~
 
diff --git a/pytest_doctestplus/plugin.py b/pytest_doctestplus/plugin.py
index 3f8e6da..d323c12 100644
--- a/pytest_doctestplus/plugin.py
+++ b/pytest_doctestplus/plugin.py
@@ -389,6 +389,10 @@ class DocTestParserPlus(doctest.DocTestParser):
              doctest chunk if the given modules/packages are not
              installed.
 
+           - ``.. doctest-requires-all:: module1, module2``: Skip all subsequent
+             doctest chunks if the given modules/packages are not
+             installed.
+
            - ``.. doctest-skip-all``: Skip all subsequent doctests.
 
            - ``.. doctest-remote-data::``: Skip the next doctest chunk if
@@ -422,10 +426,18 @@ def parse(self, s, name=None):
 
                 if isinstance(entry, str) and entry:
                     required = []
+                    required_all = []
                     skip_next = False
                     lines = entry.strip().splitlines()
+                    requires_all_match = [re.match(
+                        fr'{comment_char}\s+doctest-requires-all\s*::\s+(.*)', x) for x in lines]
+                    if any(requires_all_match):
+                        required_all = [re.split(r'\s*[,\s]\s*', match.group(1)) for match in requires_all_match if match][0]
+
+                    required_modules_all = DocTestFinderPlus.check_required_modules(required_all)
+
                     if any(re.match(
-                            f'{comment_char} doctest-skip-all', x.strip()) for x in lines):
+                            f'{comment_char} doctest-skip-all', x.strip()) for x in lines) or not required_modules_all:
                         skip_all = True
                         continue
 
diff --git a/pytest_doctestplus/sphinx/doctestplus.py b/pytest_doctestplus/sphinx/doctestplus.py
index b9b24a2..f370005 100644
--- a/pytest_doctestplus/sphinx/doctestplus.py
+++ b/pytest_doctestplus/sphinx/doctestplus.py
@@ -43,6 +43,7 @@ class DoctestRequiresDirective(DoctestSkipDirective):
 def setup(app):
 
     app.add_directive('doctest-requires', DoctestRequiresDirective)
+    app.add_directive('doctest-requires-all', DoctestRequiresDirective)
     app.add_directive('doctest-skip', DoctestSkipDirective)
     app.add_directive('doctest-skip-all', DoctestSkipDirective)
     app.add_directive('doctest', DoctestSkipDirective, override=True)
diff --git a/tests/test_doctestplus.py b/tests/test_doctestplus.py
index 6b54786..e2a3abd 100644
--- a/tests/test_doctestplus.py
+++ b/tests/test_doctestplus.py
@@ -435,6 +435,29 @@ def test_requires(testdir):
     testdir.inline_run(p, '--doctest-plus', '--doctest-rst').assertoutcome(skipped=1)
 
 
+def test_requires_all(testdir):
+    testdir.makeini(
+        """
+        [pytest]
+        doctestplus = enabled
+    """)
+
+    # should be ignored
+    p = testdir.makefile(
+        '.rst',
+        """
+        .. doctest-requires-all:: foobar
+
+            >>> import foobar
+
+        This is a narrative line, before another doctest snippet
+
+           >>> import foobar
+        """
+    )
+    testdir.inline_run(p, '--doctest-plus', '--doctest-rst').assertoutcome(skipped=1)
+
+
 def test_ignore_warnings_module(testdir):
 
     # First check that we get a warning if we don't add the IGNORE_WARNINGS