From 0e5a7c38a56878f95459e78e396e28ff214ec492 Mon Sep 17 00:00:00 2001 From: Michael Schatz Date: Fri, 7 Apr 2017 14:23:28 -0400 Subject: [PATCH] Update README.md --- README.md | 1 + 1 file changed, 1 insertion(+) diff --git a/README.md b/README.md index f6b8e29..79a0646 100644 --- a/README.md +++ b/README.md @@ -1,4 +1,5 @@ # GenomeScope: Fast genome analysis from unassembled short reads +## Vurture, GW, Sedlazeck, FJ, Nattestad, M, Underwood, CJ, Fang, H, Gurtowski, J, Schatz, MC (2017) *Bioinformatics* doi: https://doi.org/10.1093/bioinformatics/btx153 Current developments in de novo assembly technologies have been focused on relatively simple genomes. Even the human genome, with a heterozygosity rate of only ~0.1% and 2n diploid structure, is significantly simpler than many other species, especially plants. However, genomics is rapidly advancing towards sequencing more complex species such as pineapple, sugarcane, or wheat that have much higher rates of heterozygosity (>1% for pineapple), much higher ploidy (8n for sugarcane), and much larger genomes (16Gbp for wheat).