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Circular chromosomes in the VCF header #733

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nh13 opened this issue Jul 5, 2023 · 1 comment
Open

Circular chromosomes in the VCF header #733

nh13 opened this issue Jul 5, 2023 · 1 comment
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@nh13
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nh13 commented Jul 5, 2023

Similar to #403, I'd like to formalize the use of topology (especially for circular contigs) so that variants may span the origin of a circular contig without having to split into multiple records, use SV notation, etc.

@jmarshall jmarshall added the vcf label Jul 5, 2023
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jmarshall commented Jul 5, 2023

I feel like at the time we planned to extend this to VCF, but I can't find any record of that now.

I guess the natural VCF translation of the @SQ TP field would be an optional reserved attribute in §1.4.7 Contig field format, something along the lines of

topology: Molecular topology, as per SAM's @SQ TP header field. Either linear or circular.

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