diff --git a/br/pkg/lightning/backend/local/local.go b/br/pkg/lightning/backend/local/local.go
index 0d19c6887c4f8..b05091ae00bcd 100644
--- a/br/pkg/lightning/backend/local/local.go
+++ b/br/pkg/lightning/backend/local/local.go
@@ -1808,6 +1808,18 @@ func (local *local) isIngestRetryable(
 		return retryNone, nil, common.ErrKVServerIsBusy.GenWithStack(errPb.GetMessage())
 	case errPb.RegionNotFound != nil:
 		return retryNone, nil, common.ErrKVRegionNotFound.GenWithStack(errPb.GetMessage())
+	case errPb.ReadIndexNotReady != nil:
+		// this error happens when this region is splitting, the error might be:
+		//   read index not ready, reason can not read index due to split, region 64037
+		// we have paused schedule, but it's temporary,
+		// if next request takes a long time, there's chance schedule is enabled again
+		// or on key range border, another engine sharing this region tries to split this
+		// region may cause this error too.
+		newRegion, err = getRegion()
+		if err != nil {
+			return retryNone, nil, errors.Trace(err)
+		}
+		return retryWrite, newRegion, common.ErrKVReadIndexNotReady.GenWithStack(errPb.GetMessage())
 	}
 	return retryNone, nil, errors.Errorf("non-retryable error: %s", resp.GetError().GetMessage())
 }
diff --git a/br/pkg/lightning/backend/local/local_test.go b/br/pkg/lightning/backend/local/local_test.go
index 0711bfb1fc463..5ee3c31ebe13c 100644
--- a/br/pkg/lightning/backend/local/local_test.go
+++ b/br/pkg/lightning/backend/local/local_test.go
@@ -509,6 +509,15 @@ func TestIsIngestRetryable(t *testing.T) {
 	retryType, _, err = local.isIngestRetryable(ctx, resp, region, metas)
 	require.Equal(t, retryNone, retryType)
 	require.EqualError(t, err, "non-retryable error: unknown error")
+
+	resp.Error = &errorpb.Error{
+		ReadIndexNotReady: &errorpb.ReadIndexNotReady{
+			Reason: "test",
+		},
+	}
+	retryType, _, err = local.isIngestRetryable(ctx, resp, region, metas)
+	require.Equal(t, retryWrite, retryType)
+	require.Error(t, err)
 }
 
 type testIngester struct{}
diff --git a/br/pkg/lightning/common/errors.go b/br/pkg/lightning/common/errors.go
index ccb465ec4b86a..4f1c598a84535 100644
--- a/br/pkg/lightning/common/errors.go
+++ b/br/pkg/lightning/common/errors.go
@@ -70,13 +70,14 @@ var (
 	ErrCreatePDClient = errors.Normalize("create pd client error", errors.RFCCodeText("Lightning:PD:ErrCreatePDClient"))
 	ErrPauseGC        = errors.Normalize("pause gc error", errors.RFCCodeText("Lightning:PD:ErrPauseGC"))
 
-	ErrCheckKVVersion   = errors.Normalize("check tikv version error", errors.RFCCodeText("Lightning:KV:ErrCheckKVVersion"))
-	ErrCreateKVClient   = errors.Normalize("create kv client error", errors.RFCCodeText("Lightning:KV:ErrCreateKVClient"))
-	ErrCheckMultiIngest = errors.Normalize("check multi-ingest support error", errors.RFCCodeText("Lightning:KV:ErrCheckMultiIngest"))
-	ErrKVEpochNotMatch  = errors.Normalize("epoch not match", errors.RFCCodeText("Lightning:KV:EpochNotMatch"))
-	ErrKVNotLeader      = errors.Normalize("not leader", errors.RFCCodeText("Lightning:KV:NotLeader"))
-	ErrKVServerIsBusy   = errors.Normalize("server is busy", errors.RFCCodeText("Lightning:KV:ServerIsBusy"))
-	ErrKVRegionNotFound = errors.Normalize("region not found", errors.RFCCodeText("Lightning:KV:RegionNotFound"))
+	ErrCheckKVVersion      = errors.Normalize("check tikv version error", errors.RFCCodeText("Lightning:KV:ErrCheckKVVersion"))
+	ErrCreateKVClient      = errors.Normalize("create kv client error", errors.RFCCodeText("Lightning:KV:ErrCreateKVClient"))
+	ErrCheckMultiIngest    = errors.Normalize("check multi-ingest support error", errors.RFCCodeText("Lightning:KV:ErrCheckMultiIngest"))
+	ErrKVEpochNotMatch     = errors.Normalize("epoch not match", errors.RFCCodeText("Lightning:KV:EpochNotMatch"))
+	ErrKVNotLeader         = errors.Normalize("not leader", errors.RFCCodeText("Lightning:KV:NotLeader"))
+	ErrKVServerIsBusy      = errors.Normalize("server is busy", errors.RFCCodeText("Lightning:KV:ServerIsBusy"))
+	ErrKVRegionNotFound    = errors.Normalize("region not found", errors.RFCCodeText("Lightning:KV:RegionNotFound"))
+	ErrKVReadIndexNotReady = errors.Normalize("read index not ready", errors.RFCCodeText("Lightning:KV:ReadIndexNotReady"))
 
 	ErrUnknownBackend     = errors.Normalize("unknown backend %s", errors.RFCCodeText("Lightning:Restore:ErrUnknownBackend"))
 	ErrCheckLocalFile     = errors.Normalize("cannot find local file for table: %s engineDir: %s", errors.RFCCodeText("Lightning:Restore:ErrCheckLocalFile"))
diff --git a/errors.toml b/errors.toml
index d8112d297e6fe..c9e3aa6c9da9b 100755
--- a/errors.toml
+++ b/errors.toml
@@ -371,6 +371,11 @@ error = '''
 not leader
 '''
 
+["Lightning:KV:ReadIndexNotReady"]
+error = '''
+read index not ready
+'''
+
 ["Lightning:KV:RegionNotFound"]
 error = '''
 region not found