diff --git a/ext/opentelemetry-ext-requests/src/opentelemetry/ext/requests/__init__.py b/ext/opentelemetry-ext-requests/src/opentelemetry/ext/requests/__init__.py
index c98a24cc885..2a82e9820cb 100644
--- a/ext/opentelemetry-ext-requests/src/opentelemetry/ext/requests/__init__.py
+++ b/ext/opentelemetry-ext-requests/src/opentelemetry/ext/requests/__init__.py
@@ -55,7 +55,7 @@
 
 
 # pylint: disable=unused-argument
-def _instrument(tracer_provider=None):
+def _instrument(tracer_provider=None, span_callback=None):
     """Enables tracing of all requests calls that go through
       :code:`requests.session.Session.request` (this includes
       :code:`requests.get`, etc.)."""
@@ -101,6 +101,8 @@ def instrumented_request(self, method, url, *args, **kwargs):
             span.set_status(
                 Status(_http_status_to_canonical_code(result.status_code))
             )
+            if span_callback is not None:
+                span_callback(span, result)
 
             return result
 
@@ -156,8 +158,22 @@ def _http_status_to_canonical_code(code: int, allow_redirect: bool = True):
 
 
 class RequestsInstrumentor(BaseInstrumentor):
+    """An instrumentor for requests
+    See `BaseInstrumentor`
+    """
+
     def _instrument(self, **kwargs):
-        _instrument(tracer_provider=kwargs.get("tracer_provider"))
+        """Instruments requests module
+
+        Args:
+            **kwargs: Optional arguments
+                ``tracer_provider``: a TracerProvider, defaults to global
+                ``span_callback``: An optional callback invoked before returning the http response. Invoked with Span and requests.Response
+        """
+        _instrument(
+            tracer_provider=kwargs.get("tracer_provider"),
+            span_callback=kwargs.get("span_callback"),
+        )
 
     def _uninstrument(self, **kwargs):
         _uninstrument()
diff --git a/ext/opentelemetry-ext-requests/tests/test_requests_integration.py b/ext/opentelemetry-ext-requests/tests/test_requests_integration.py
index 7764aad3ec5..28359d8f38a 100644
--- a/ext/opentelemetry-ext-requests/tests/test_requests_integration.py
+++ b/ext/opentelemetry-ext-requests/tests/test_requests_integration.py
@@ -183,6 +183,37 @@ def test_distributed_context(self):
         finally:
             propagators.set_global_httptextformat(previous_propagator)
 
+    def test_span_callback(self):
+        RequestsInstrumentor().uninstrument()
+
+        def span_callback(span, result: requests.Response):
+            span.set_attribute(
+                "http.response.body", result.content.decode("utf-8")
+            )
+
+        RequestsInstrumentor().instrument(
+            tracer_provider=self.tracer_provider, span_callback=span_callback,
+        )
+
+        result = requests.get(self.URL)
+        self.assertEqual(result.text, "Hello!")
+
+        span_list = self.memory_exporter.get_finished_spans()
+        self.assertEqual(len(span_list), 1)
+        span = span_list[0]
+
+        self.assertEqual(
+            span.attributes,
+            {
+                "component": "http",
+                "http.method": "GET",
+                "http.url": self.URL,
+                "http.status_code": 200,
+                "http.status_text": "OK",
+                "http.response.body": "Hello!",
+            },
+        )
+
     def test_custom_tracer_provider(self):
         resource = resources.Resource.create({})
         result = self.create_tracer_provider(resource=resource)