diff --git a/instrumentation/opentelemetry-instrumentation-httpx/pyproject.toml b/instrumentation/opentelemetry-instrumentation-httpx/pyproject.toml
index 873b40e3a8..61e1bc4b6e 100644
--- a/instrumentation/opentelemetry-instrumentation-httpx/pyproject.toml
+++ b/instrumentation/opentelemetry-instrumentation-httpx/pyproject.toml
@@ -32,7 +32,7 @@ dependencies = [
 
 [project.optional-dependencies]
 instruments = [
-  "httpx >= 0.18.0",
+  "httpx >= 0.18.0, <= 0.23.0",
 ]
 test = [
   "opentelemetry-instrumentation-httpx[instruments]",
diff --git a/opentelemetry-instrumentation/src/opentelemetry/instrumentation/bootstrap_gen.py b/opentelemetry-instrumentation/src/opentelemetry/instrumentation/bootstrap_gen.py
index aabbd0a6d0..2e5cc794a6 100644
--- a/opentelemetry-instrumentation/src/opentelemetry/instrumentation/bootstrap_gen.py
+++ b/opentelemetry-instrumentation/src/opentelemetry/instrumentation/bootstrap_gen.py
@@ -81,7 +81,7 @@
         "instrumentation": "opentelemetry-instrumentation-grpc==0.36b0.dev",
     },
     "httpx": {
-        "library": "httpx >= 0.18.0",
+        "library": "httpx >= 0.18.0, <= 0.23.0",
         "instrumentation": "opentelemetry-instrumentation-httpx==0.36b0.dev",
     },
     "jinja2": {