diff --git a/.github/workflows/instrumentations_1.yml b/.github/workflows/instrumentations_1.yml
index 0640c056a6..978642a7a3 100644
--- a/.github/workflows/instrumentations_1.yml
+++ b/.github/workflows/instrumentations_1.yml
@@ -25,7 +25,7 @@ jobs:
         python-version: [py38, py39, py310, py311, pypy3]
         package:
           - "urllib"
-          - "urllib3v"
+          - "urllib3"
           - "wsgi"
           - "distro"
           - "richconsole"
diff --git a/instrumentation/opentelemetry-instrumentation-urllib3/pyproject.toml b/instrumentation/opentelemetry-instrumentation-urllib3/pyproject.toml
index fbd27f7bd8..628cb46554 100644
--- a/instrumentation/opentelemetry-instrumentation-urllib3/pyproject.toml
+++ b/instrumentation/opentelemetry-instrumentation-urllib3/pyproject.toml
@@ -35,11 +35,6 @@ dependencies = [
 instruments = [
   "urllib3 >= 1.0.0, < 3.0.0",
 ]
-test = [
-  "opentelemetry-instrumentation-urllib3[instruments]",
-  "httpretty ~= 1.0",
-  "opentelemetry-test-utils == 0.45b0.dev",
-]
 
 [project.entry-points.opentelemetry_instrumentor]
 urllib3 = "opentelemetry.instrumentation.urllib3:URLLib3Instrumentor"
diff --git a/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-0.txt b/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-0.txt
new file mode 100644
index 0000000000..730ef16977
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-0.txt
@@ -0,0 +1,20 @@
+asgiref==3.7.2
+attrs==23.2.0
+Deprecated==1.2.14
+httpretty==1.1.4
+importlib-metadata==6.11.0
+iniconfig==2.0.0
+packaging==23.2
+pluggy==1.4.0
+py==1.11.0
+py-cpuinfo==9.0.0
+pytest==7.1.3
+pytest-benchmark==4.0.0
+tomli==2.0.1
+typing_extensions==4.10.0
+urllib3==1.26.18
+wrapt==1.16.0
+zipp==3.17.0
+-e opentelemetry-instrumentation
+-e util/opentelemetry-util-http
+-e instrumentation/opentelemetry-instrumentation-urllib3
diff --git a/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-1.txt b/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-1.txt
new file mode 100644
index 0000000000..1f10502f57
--- /dev/null
+++ b/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-1.txt
@@ -0,0 +1,20 @@
+asgiref==3.7.2
+attrs==23.2.0
+Deprecated==1.2.14
+httpretty==1.1.4
+importlib-metadata==6.11.0
+iniconfig==2.0.0
+packaging==23.2
+pluggy==1.4.0
+py==1.11.0
+py-cpuinfo==9.0.0
+pytest==7.1.3
+pytest-benchmark==4.0.0
+tomli==2.0.1
+typing_extensions==4.10.0
+urllib3==2.2.1
+wrapt==1.16.0
+zipp==3.17.0
+-e opentelemetry-instrumentation
+-e util/opentelemetry-util-http
+-e instrumentation/opentelemetry-instrumentation-urllib3
diff --git a/tox.ini b/tox.ini
index b59ee8d21b..d7c30a8e7b 100644
--- a/tox.ini
+++ b/tox.ini
@@ -110,8 +110,12 @@ envlist =
     pypy3-test-instrumentation-urllib
 
     ; opentelemetry-instrumentation-urllib3
-    py3{8,9,10,11}-test-instrumentation-urllib3v-{1,2}
-    pypy3-test-instrumentation-urllib3v-{1,2}
+    ; The numbers at the end of the environment names
+    ; below mean these dependencies are being used:
+    ; 0: urllib3 >=1.0.0,<2.0.0
+    ; 1: urllib3 >=2.0.0,<3.0.0
+    py3{8,9,10,11}-test-instrumentation-urllib3-{0,1}
+    pypy3-test-instrumentation-urllib3-{0,1}
 
     ; opentelemetry-instrumentation-requests
     py3{8,9,10,11}-test-instrumentation-requests
@@ -300,8 +304,6 @@ deps =
   pymemcache-300: pymemcache >3.0.0,<3.4.2
   pymemcache-342: pymemcache ==3.4.2
   pymemcache-400: pymemcache ==4.0.0
-  urllib3v-1: urllib3 >=1.0.0,<2.0.0
-  urllib3v-2: urllib3 >=2.0.0,<3.0.0
 
   ; FIXME: add coverage testing
   ; FIXME: add mypy testing
@@ -341,8 +343,6 @@ commands_pre =
 
   grpc: pip install {toxinidir}/instrumentation/opentelemetry-instrumentation-grpc[test]
 
-  urllib3v-{1,2}: pip install {toxinidir}/util/opentelemetry-util-http
-
   wsgi: pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-wsgi/test-requirements.txt
 
   asyncpg: pip install {toxinidir}/instrumentation/opentelemetry-instrumentation-asyncpg[test]
@@ -364,7 +364,8 @@ commands_pre =
 
   urllib: pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib/test-requirements.txt
 
-  urllib3v-{1,2}: pip install {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3[test]
+  urllib3-0: pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-0.txt
+  urllib3-1: pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-1.txt
 
   botocore: pip install {toxinidir}/instrumentation/opentelemetry-instrumentation-botocore[test]
 
@@ -479,7 +480,7 @@ commands =
   test-instrumentation-fastapi: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-fastapi/tests {posargs}
   test-instrumentation-flask: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-flask/tests {posargs}
   test-instrumentation-urllib: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib/tests {posargs}
-  test-instrumentation-urllib3v: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3/tests {posargs}
+  test-instrumentation-urllib3: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3/tests {posargs}
   test-instrumentation-grpc: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-grpc/tests {posargs}
   test-instrumentation-jinja2: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-jinja2/tests {posargs}
   test-instrumentation-kafka-python: pytest {toxinidir}/instrumentation/opentelemetry-instrumentation-kafka-python/tests {posargs}
@@ -591,7 +592,7 @@ commands_pre =
   pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-pyramid/test-requirements.txt
   pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-requests/test-requirements.txt
   pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib/test-requirements.txt
-  python -m pip install -e {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3[test]
+  pip install -r {toxinidir}/instrumentation/opentelemetry-instrumentation-urllib3/test-requirements-1.txt
   python -m pip install -e {toxinidir}/instrumentation/opentelemetry-instrumentation-pymysql[test]
   # prerequisite: follow the instructions here https://github.com/PyMySQL/mysqlclient#install
   # for your OS to install the required dependencies