diff --git a/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TBinaryProtocol.cs b/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TBinaryProtocol.cs
index 820f5ee51a5..4a3454aa40f 100644
--- a/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TBinaryProtocol.cs
+++ b/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TBinaryProtocol.cs
@@ -192,7 +192,7 @@ public override void WriteDouble(double d)
             WriteI64(BitConverter.DoubleToInt64Bits(d));
         }
 
-#if NETSTANDARD2_1_OR_GREATER
+#if NETSTANDARD2_1_OR_GREATER || NET6_0_OR_GREATER
         public override void WriteBinary(ReadOnlySpan<byte> bytes)
         {
             WriteI32(bytes.Length);
diff --git a/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TCompactProtocol.cs b/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TCompactProtocol.cs
index 29155a4eec1..75f62278d35 100644
--- a/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TCompactProtocol.cs
+++ b/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TCompactProtocol.cs
@@ -356,7 +356,7 @@ public override void WriteDouble(double d)
             Transport.Write(PreAllocatedBuffer, 0, 8);
         }
 
-#if NETSTANDARD2_1_OR_GREATER
+#if NETSTANDARD2_1_OR_GREATER || NET6_0_OR_GREATER
         public override void WriteBinary(ReadOnlySpan<byte> bytes)
         {
             Int32ToVarInt((uint)bytes.Length, ref PreAllocatedVarInt);
diff --git a/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TProtocol.cs b/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TProtocol.cs
index fdba44886d7..ae88af98a4c 100644
--- a/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TProtocol.cs
+++ b/src/OpenTelemetry.Exporter.Jaeger/ApacheThrift/Protocol/TProtocol.cs
@@ -143,7 +143,7 @@ protected virtual void Dispose(bool disposing)
 
         public virtual void WriteString(string s)
         {
-#if NETSTANDARD2_1_OR_GREATER
+#if NETSTANDARD2_1_OR_GREATER || NET6_0_OR_GREATER
             if (s.Length <= 128)
             {
                 Span<byte> buffer = stackalloc byte[256];
@@ -165,7 +165,7 @@ public virtual void WriteString(string s)
             }
         }
 
-#if NETSTANDARD2_1_OR_GREATER
+#if NETSTANDARD2_1_OR_GREATER || NET6_0_OR_GREATER
         public abstract void WriteBinary(ReadOnlySpan<byte> bytes);
 #endif
 
diff --git a/src/OpenTelemetry.Exporter.Jaeger/CHANGELOG.md b/src/OpenTelemetry.Exporter.Jaeger/CHANGELOG.md
index cf675a45c3f..80d91226941 100644
--- a/src/OpenTelemetry.Exporter.Jaeger/CHANGELOG.md
+++ b/src/OpenTelemetry.Exporter.Jaeger/CHANGELOG.md
@@ -2,6 +2,9 @@
 
 ## Unreleased
 
+* Enabled performance optimizations for .NET 6.0+ runtimes.
+  ([#4349](https://github.com/open-telemetry/opentelemetry-dotnet/pull/4349))
+
 ## 1.5.0-alpha.1
 
 Released 2023-Mar-07