diff --git a/bazel/repository.bzl b/bazel/repository.bzl
index 58245494ac..9ba8ad5388 100644
--- a/bazel/repository.bzl
+++ b/bazel/repository.bzl
@@ -111,10 +111,10 @@ def opentelemetry_cpp_deps():
         http_archive,
         name = "com_github_opentelemetry_proto",
         build_file = "@io_opentelemetry_cpp//bazel:opentelemetry_proto.BUILD",
-        sha256 = "516dc94685dbaa14fb792788f31d2ef2b0c3ad08dfa8a9a8164e3cf60c1ab6f7",
-        strip_prefix = "opentelemetry-proto-1.2.0",
+        sha256 = "bed250ceec8e4a83aa5604d7d5595a61945059dc662edd058a9da082283f7a00",
+        strip_prefix = "opentelemetry-proto-1.3.1",
         urls = [
-            "https://github.com/open-telemetry/opentelemetry-proto/archive/v1.2.0.tar.gz",
+            "https://github.com/open-telemetry/opentelemetry-proto/archive/v1.3.1.tar.gz",
         ],
     )
 
diff --git a/cmake/opentelemetry-proto.cmake b/cmake/opentelemetry-proto.cmake
index 2208235691..c2982e23c0 100644
--- a/cmake/opentelemetry-proto.cmake
+++ b/cmake/opentelemetry-proto.cmake
@@ -72,13 +72,18 @@ set(TRACE_PROTO "${PROTO_PATH}/opentelemetry/proto/trace/v1/trace.proto")
 set(LOGS_PROTO "${PROTO_PATH}/opentelemetry/proto/logs/v1/logs.proto")
 set(METRICS_PROTO "${PROTO_PATH}/opentelemetry/proto/metrics/v1/metrics.proto")
 
+set(PROFILES_PROTO "${PROTO_PATH}/opentelemetry/proto/profiles/v1experimental/profiles.proto")
+set(PROFILES_EXT_PROTO "${PROTO_PATH}/opentelemetry/proto/profiles/v1experimental/pprofextended.proto")
+
 set(TRACE_SERVICE_PROTO
     "${PROTO_PATH}/opentelemetry/proto/collector/trace/v1/trace_service.proto")
 set(LOGS_SERVICE_PROTO
     "${PROTO_PATH}/opentelemetry/proto/collector/logs/v1/logs_service.proto")
 set(METRICS_SERVICE_PROTO
-    "${PROTO_PATH}/opentelemetry/proto/collector/metrics/v1/metrics_service.proto"
-)
+    "${PROTO_PATH}/opentelemetry/proto/collector/metrics/v1/metrics_service.proto")
+
+set(PROFILES_SERVICE_PROTO
+    "${PROTO_PATH}/opentelemetry/proto/collector/profiles/v1experimental/profiles_service.proto")
 
 set(GENERATED_PROTOBUF_PATH
     "${CMAKE_BINARY_DIR}/generated/third_party/opentelemetry-proto")
@@ -112,6 +117,34 @@ set(TRACE_SERVICE_PB_CPP_FILE
 set(TRACE_SERVICE_PB_H_FILE
     "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/collector/trace/v1/trace_service.pb.h"
 )
+
+#
+# Notes about the PROFILES signal:
+# - *.proto files added in opentelemetry-proto 1.3.0
+# - C++ code is generated from proto files
+# - The generated code is not used yet.
+#
+
+set(PROFILES_CPP_FILE
+    "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/profiles/v1experimental/profiles.pb.cc")
+set(PROFILES_H_FILE
+    "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/profiles/v1experimental/profiles.pb.h")
+set(PROFILES_EXT_CPP_FILE
+    "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/profiles/v1experimental/pprofextended.pb.cc")
+set(PROFILES_EXT_H_FILE
+    "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/profiles/v1experimental/pprofextended.pb.h")
+set(PROFILES_SERVICE_PB_H_FILE
+    "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/collector/profiles/v1experimental/profiles_service.pb.h")
+set(PROFILES_SERVICE_PB_CPP_FILE
+    "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/collector/profiles/v1experimental/profiles_service.pb.cc")
+
+if(WITH_OTLP_GRPC)
+  set(PROFILES_SERVICE_GRPC_PB_H_FILE
+      "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/collector/profiles/v1experimental/profiles_service.grpc.pb.h")
+  set(PROFILES_SERVICE_GRPC_PB_CPP_FILE
+      "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/collector/profiles/v1experimental/profiles_service.grpc.pb.cc")
+endif()
+
 if(WITH_OTLP_GRPC)
   set(TRACE_SERVICE_GRPC_PB_CPP_FILE
       "${GENERATED_PROTOBUF_PATH}/opentelemetry/proto/collector/trace/v1/trace_service.grpc.pb.cc"
@@ -188,12 +221,18 @@ set(PROTOBUF_GENERATED_FILES
     ${LOGS_PB_CPP_FILE}
     ${METRICS_PB_H_FILE}
     ${METRICS_PB_CPP_FILE}
+    ${PROFILES_H_FILE}
+    ${PROFILES_CPP_FILE}
+    ${PROFILES_EXT_H_FILE}
+    ${PROFILES_EXT_CPP_FILE}
     ${TRACE_SERVICE_PB_H_FILE}
     ${TRACE_SERVICE_PB_CPP_FILE}
     ${LOGS_SERVICE_PB_H_FILE}
     ${LOGS_SERVICE_PB_CPP_FILE}
     ${METRICS_SERVICE_PB_H_FILE}
-    ${METRICS_SERVICE_PB_CPP_FILE})
+    ${METRICS_SERVICE_PB_CPP_FILE}
+    ${PROFILES_SERVICE_PB_H_FILE}
+    ${PROFILES_SERVICE_PB_CPP_FILE})
 
 if(WITH_OTLP_GRPC)
   list(APPEND PROTOBUF_COMMON_FLAGS
@@ -208,7 +247,9 @@ if(WITH_OTLP_GRPC)
     ${LOGS_SERVICE_GRPC_PB_H_FILE}
     ${LOGS_SERVICE_GRPC_PB_CPP_FILE}
     ${METRICS_SERVICE_GRPC_PB_H_FILE}
-    ${METRICS_SERVICE_GRPC_PB_CPP_FILE})
+    ${METRICS_SERVICE_GRPC_PB_CPP_FILE}
+    ${PROFILES_SERVICE_GRPC_PB_H_FILE}
+    ${PROFILES_SERVICE_GRPC_PB_CPP_FILE})
 endif()
 
 set(PROTOBUF_RUN_PROTOC_COMMAND "\"${PROTOBUF_PROTOC_EXECUTABLE}\"")
@@ -221,9 +262,12 @@ foreach(
   ${TRACE_PROTO}
   ${LOGS_PROTO}
   ${METRICS_PROTO}
+  ${PROFILES_PROTO}
+  ${PROFILES_EXT_PROTO}
   ${TRACE_SERVICE_PROTO}
   ${LOGS_SERVICE_PROTO}
-  ${METRICS_SERVICE_PROTO})
+  ${METRICS_SERVICE_PROTO}
+  ${PROFILES_SERVICE_PROTO})
   set(PROTOBUF_RUN_PROTOC_COMMAND
       "${PROTOBUF_RUN_PROTOC_COMMAND} \"${PROTOBUF_RUN_PROTOC_ARG}\"")
 endforeach()
@@ -235,6 +279,7 @@ add_custom_command(
     ${PROTOBUF_INCLUDE_FLAGS} ${COMMON_PROTO} ${RESOURCE_PROTO} ${TRACE_PROTO}
     ${LOGS_PROTO} ${METRICS_PROTO} ${TRACE_SERVICE_PROTO} ${LOGS_SERVICE_PROTO}
     ${METRICS_SERVICE_PROTO}
+    ${PROFILES_PROTO} ${PROFILES_EXT_PROTO} ${PROFILES_SERVICE_PROTO}
   COMMENT "[Run]: ${PROTOBUF_RUN_PROTOC_COMMAND}")
 
 include_directories("${GENERATED_PROTOBUF_PATH}")
diff --git a/third_party/opentelemetry-proto b/third_party/opentelemetry-proto
index 24d4bc0020..b3060d2104 160000
--- a/third_party/opentelemetry-proto
+++ b/third_party/opentelemetry-proto
@@ -1 +1 @@
-Subproject commit 24d4bc002003c74db7aa608c8e254155daf8e49d
+Subproject commit b3060d2104df364136d75a35779e6bd48bac449a