diff --git a/lib/internal/process/per_thread.js b/lib/internal/process/per_thread.js
index b061dd340c78cc..b16705f9fb95b0 100644
--- a/lib/internal/process/per_thread.js
+++ b/lib/internal/process/per_thread.js
@@ -6,18 +6,21 @@
 
 const {
   ArrayIsArray,
+  ArrayPrototypeMap,
+  ArrayPrototypePush,
+  ArrayPrototypeSplice,
   BigUint64Array,
   Float64Array,
   NumberMAX_SAFE_INTEGER,
-  ObjectDefineProperties,
   ObjectDefineProperty,
   ObjectFreeze,
-  ObjectGetOwnPropertyDescriptors,
+  ReflectApply,
   RegExpPrototypeTest,
-  Set,
-  SetPrototype,
-  SetPrototypeHas,
+  SafeSet,
+  StringPrototypeEndsWith,
   StringPrototypeReplace,
+  StringPrototypeSlice,
+  StringPrototypeStartsWith,
   Uint32Array,
 } = primordials;
 
@@ -94,7 +97,7 @@ function wrapProcessMethods(binding) {
   } = binding;
 
   function _rawDebug(...args) {
-    binding._rawDebug(format.apply(null, args));
+    binding._rawDebug(ReflectApply(format, null, args));
   }
 
   // Create the argument array that will be passed to the native function.
@@ -256,19 +259,19 @@ function buildAllowedFlags() {
   const allowedNodeEnvironmentFlags = [];
   for (const [name, info] of options) {
     if (info.envVarSettings === kAllowedInEnvironment) {
-      allowedNodeEnvironmentFlags.push(name);
+      ArrayPrototypePush(allowedNodeEnvironmentFlags, name);
     }
   }
 
   for (const [ from, expansion ] of aliases) {
     let isAccepted = true;
     for (const to of expansion) {
-      if (!to.startsWith('-') || to === '--') continue;
+      if (!StringPrototypeStartsWith(to, '-') || to === '--') continue;
       const recursiveExpansion = aliases.get(to);
       if (recursiveExpansion) {
         if (recursiveExpansion[0] === to)
-          recursiveExpansion.splice(0, 1);
-        expansion.push(...recursiveExpansion);
+          ArrayPrototypeSplice(recursiveExpansion, 0, 1);
+        ArrayPrototypePush(expansion, ...recursiveExpansion);
         continue;
       }
       isAccepted = options.get(to).envVarSettings === kAllowedInEnvironment;
@@ -276,11 +279,11 @@ function buildAllowedFlags() {
     }
     if (isAccepted) {
       let canonical = from;
-      if (canonical.endsWith('='))
-        canonical = canonical.substr(0, canonical.length - 1);
-      if (canonical.endsWith(' <arg>'))
-        canonical = canonical.substr(0, canonical.length - 4);
-      allowedNodeEnvironmentFlags.push(canonical);
+      if (StringPrototypeEndsWith(canonical, '='))
+        canonical = StringPrototypeSlice(canonical, 0, canonical.length - 1);
+      if (StringPrototypeEndsWith(canonical, ' <arg>'))
+        canonical = StringPrototypeSlice(canonical, 0, canonical.length - 4);
+      ArrayPrototypePush(allowedNodeEnvironmentFlags, canonical);
     }
   }
 
@@ -289,14 +292,10 @@ function buildAllowedFlags() {
 
   // Save these for comparison against flags provided to
   // process.allowedNodeEnvironmentFlags.has() which lack leading dashes.
-  // Avoid interference w/ user code by flattening `Set.prototype` into
-  // each object.
-  const nodeFlags = ObjectDefineProperties(
-    new Set(allowedNodeEnvironmentFlags.map(trimLeadingDashes)),
-    ObjectGetOwnPropertyDescriptors(SetPrototype)
-  );
-
-  class NodeEnvironmentFlagsSet extends Set {
+  const nodeFlags = new SafeSet(ArrayPrototypeMap(allowedNodeEnvironmentFlags,
+                                                  trimLeadingDashes));
+
+  class NodeEnvironmentFlagsSet extends SafeSet {
     constructor(...args) {
       super(...args);
 
@@ -328,9 +327,9 @@ function buildAllowedFlags() {
         key = StringPrototypeReplace(key, replaceUnderscoresRegex, '-');
         if (RegExpPrototypeTest(leadingDashesRegex, key)) {
           key = StringPrototypeReplace(key, trailingValuesRegex, '');
-          return SetPrototypeHas(this, key);
+          return super.has(key);
         }
-        return SetPrototypeHas(nodeFlags, key);
+        return nodeFlags.has(key);
       }
       return false;
     }
diff --git a/lib/internal/process/promises.js b/lib/internal/process/promises.js
index ad21152dd12a08..023f7df0360d02 100644
--- a/lib/internal/process/promises.js
+++ b/lib/internal/process/promises.js
@@ -1,9 +1,11 @@
 'use strict';
 
 const {
+  ArrayPrototypePush,
+  ArrayPrototypeShift,
   Error,
   ObjectDefineProperty,
-  WeakMap,
+  SafeWeakMap,
 } = primordials;
 
 const {
@@ -25,7 +27,7 @@ const {
 // *Must* match Environment::TickInfo::Fields in src/env.h.
 const kHasRejectionToWarn = 1;
 
-const maybeUnhandledPromises = new WeakMap();
+const maybeUnhandledPromises = new SafeWeakMap();
 const pendingUnhandledRejections = [];
 const asyncHandledRejections = [];
 let lastPromiseId = 0;
@@ -121,7 +123,7 @@ function unhandledRejection(promise, reason) {
     domain: process.domain
   });
   // This causes the promise to be referenced at least for one tick.
-  pendingUnhandledRejections.push(promise);
+  ArrayPrototypePush(pendingUnhandledRejections, promise);
   setHasRejectionToWarn(true);
 }
 
@@ -137,7 +139,7 @@ function handledRejection(promise) {
                                 `asynchronously (rejection id: ${uid})`);
       warning.name = 'PromiseRejectionHandledWarning';
       warning.id = uid;
-      asyncHandledRejections.push({ promise, warning });
+      ArrayPrototypePush(asyncHandledRejections, { promise, warning });
       setHasRejectionToWarn(true);
       return;
     }
@@ -178,7 +180,7 @@ function processPromiseRejections() {
   let maybeScheduledTicksOrMicrotasks = asyncHandledRejections.length > 0;
 
   while (asyncHandledRejections.length > 0) {
-    const { promise, warning } = asyncHandledRejections.shift();
+    const { promise, warning } = ArrayPrototypeShift(asyncHandledRejections);
     if (!process.emit('rejectionHandled', promise)) {
       process.emitWarning(warning);
     }
@@ -186,7 +188,7 @@ function processPromiseRejections() {
 
   let len = pendingUnhandledRejections.length;
   while (len--) {
-    const promise = pendingUnhandledRejections.shift();
+    const promise = ArrayPrototypeShift(pendingUnhandledRejections);
     const promiseInfo = maybeUnhandledPromises.get(promise);
     if (promiseInfo === undefined) {
       continue;
diff --git a/lib/internal/process/signal.js b/lib/internal/process/signal.js
index abc2b93dbfb7f3..0631fe2b29ab01 100644
--- a/lib/internal/process/signal.js
+++ b/lib/internal/process/signal.js
@@ -1,7 +1,8 @@
 'use strict';
 
 const {
-  Map,
+  FunctionPrototypeBind,
+  SafeMap,
 } = primordials;
 
 const {
@@ -11,7 +12,7 @@ const {
 const { signals } = internalBinding('constants').os;
 
 let Signal;
-const signalWraps = new Map();
+const signalWraps = new SafeMap();
 
 function isSignal(event) {
   return typeof event === 'string' && signals[event] !== undefined;
@@ -26,7 +27,7 @@ function startListeningIfSignal(type) {
 
     wrap.unref();
 
-    wrap.onsignal = process.emit.bind(process, type, type);
+    wrap.onsignal = FunctionPrototypeBind(process.emit, process, type, type);
 
     const signum = signals[type];
     const err = wrap.start(signum);