diff --git a/common.gypi b/common.gypi
index 52636bb2fac590..1dca7c9a106e2e 100644
--- a/common.gypi
+++ b/common.gypi
@@ -36,7 +36,7 @@
 
     # Reset this number to 0 on major V8 upgrades.
     # Increment by one for each non-official patch applied to deps/v8.
-    'v8_embedder_string': '-node.20',
+    'v8_embedder_string': '-node.21',
 
     ##### V8 defaults for Node.js #####
 
diff --git a/deps/v8/src/objects/js-function.cc b/deps/v8/src/objects/js-function.cc
index 1640cb0d31529c..94f7a672a704e1 100644
--- a/deps/v8/src/objects/js-function.cc
+++ b/deps/v8/src/objects/js-function.cc
@@ -676,6 +676,10 @@ void SetInstancePrototype(Isolate* isolate, Handle<JSFunction> function,
       // At that point, a new initial map is created and the prototype is put
       // into the initial map where it belongs.
       function->set_prototype_or_initial_map(*value, kReleaseStore);
+      if (value->IsJSObjectThatCanBeTrackedAsPrototype()) {
+        // Optimize as prototype to detach it from its transition tree.
+        JSObject::OptimizeAsPrototype(Handle<JSObject>::cast(value));
+      }
     } else {
       Handle<Map> new_map =
           Map::Copy(isolate, initial_map, "SetInstancePrototype");
@@ -801,8 +805,10 @@ void JSFunction::EnsureHasInitialMap(Handle<JSFunction> function) {
   Handle<HeapObject> prototype;
   if (function->has_instance_prototype()) {
     prototype = handle(function->instance_prototype(), isolate);
+    map->set_prototype(*prototype);
   } else {
     prototype = isolate->factory()->NewFunctionPrototype(function);
+    Map::SetPrototype(isolate, map, prototype);
   }
   DCHECK(map->has_fast_object_elements());