diff --git a/jetstream/jetstream.go b/jetstream/jetstream.go
index 8f4e545d7..f7a30a476 100644
--- a/jetstream/jetstream.go
+++ b/jetstream/jetstream.go
@@ -158,6 +158,7 @@ type (
 	}
 	streamInfoResponse struct {
 		apiResponse
+		apiPaged
 		*StreamInfo
 	}
 
diff --git a/jetstream/options.go b/jetstream/options.go
index ae2941082..52f9054bd 100644
--- a/jetstream/options.go
+++ b/jetstream/options.go
@@ -264,7 +264,11 @@ func WithDeletedDetails(deletedDetails bool) StreamInfoOpt {
 	}
 }
 
-// WithSubjectFilter can be used to display the information about messages stored on given subjects
+// WithSubjectFilter can be used to display the information about messages
+// stored on given subjects.
+// NOTE: if the subject filter matches over 100k
+// subjects, this will result in multiple requests to the server to retrieve all
+// the information, and all of the returned subjects will be kept in memory.
 func WithSubjectFilter(subject string) StreamInfoOpt {
 	return func(req *streamInfoRequest) error {
 		req.SubjectFilter = subject
diff --git a/jetstream/stream.go b/jetstream/stream.go
index e864cf164..a5c6492e8 100644
--- a/jetstream/stream.go
+++ b/jetstream/stream.go
@@ -102,6 +102,7 @@ type (
 	StreamInfoOpt func(*streamInfoRequest) error
 
 	streamInfoRequest struct {
+		apiPaged
 		DeletedDetails bool   `json:"deleted_details,omitempty"`
 		SubjectFilter  string `json:"subjects_filter,omitempty"`
 	}
@@ -259,28 +260,56 @@ func (s *stream) Info(ctx context.Context, opts ...StreamInfoOpt) (*StreamInfo,
 	}
 	var req []byte
 	var err error
-	if infoReq != nil {
-		req, err = json.Marshal(infoReq)
-		if err != nil {
-			return nil, err
-		}
-	}
+	var subjectMap map[string]uint64
+	var offset int
 
 	infoSubject := apiSubj(s.jetStream.apiPrefix, fmt.Sprintf(apiStreamInfoT, s.name))
-	var resp streamInfoResponse
-
-	if _, err = s.jetStream.apiRequestJSON(ctx, infoSubject, &resp, req); err != nil {
-		return nil, err
-	}
-	if resp.Error != nil {
-		if resp.Error.ErrorCode == JSErrCodeConsumerNotFound {
-			return nil, ErrStreamNotFound
+	var info *StreamInfo
+	for {
+		if infoReq != nil {
+			if infoReq.SubjectFilter != "" {
+				if subjectMap == nil {
+					subjectMap = make(map[string]uint64)
+				}
+				infoReq.Offset = offset
+			}
+			req, err = json.Marshal(infoReq)
+			if err != nil {
+				return nil, err
+			}
+		}
+		var resp streamInfoResponse
+		if _, err = s.jetStream.apiRequestJSON(ctx, infoSubject, &resp, req); err != nil {
+			return nil, err
+		}
+		if resp.Error != nil {
+			if resp.Error.ErrorCode == JSErrCodeStreamNotFound {
+				return nil, ErrStreamNotFound
+			}
+			return nil, resp.Error
+		}
+		info = resp.StreamInfo
+		var total int
+		if resp.Total != 0 {
+			total = resp.Total
+		}
+		if len(resp.StreamInfo.State.Subjects) > 0 {
+			for subj, msgs := range resp.StreamInfo.State.Subjects {
+				subjectMap[subj] = msgs
+			}
+			offset = len(subjectMap)
+		}
+		if total == 0 || total <= offset {
+			info.State.Subjects = nil
+			// we don't want to store subjects in cache
+			cached := *info
+			s.info = &cached
+			info.State.Subjects = subjectMap
+			break
 		}
-		return nil, resp.Error
 	}
-	s.info = resp.StreamInfo
 
-	return resp.StreamInfo, nil
+	return info, nil
 }
 
 // CachedInfo returns *StreamInfo cached on a stream struct
diff --git a/jetstream/test/stream_test.go b/jetstream/test/stream_test.go
index bb85f67d9..ca1009084 100644
--- a/jetstream/test/stream_test.go
+++ b/jetstream/test/stream_test.go
@@ -610,6 +610,48 @@ func TestStreamInfo(t *testing.T) {
 	}
 }
 
+func TestSubjectsFilterPaging(t *testing.T) {
+	srv := RunBasicJetStreamServer()
+	defer shutdownJSServerAndRemoveStorage(t, srv)
+
+	nc, err := nats.Connect(srv.ClientURL())
+	if err != nil {
+		t.Fatalf("Unexpected error: %v", err)
+	}
+	defer nc.Close()
+	js, err := jetstream.New(nc)
+	if err != nil {
+		t.Fatalf("Unexpected error: %v", err)
+	}
+
+	s, err := js.CreateStream(context.Background(), jetstream.StreamConfig{Name: "foo", Subjects: []string{"FOO.*"}})
+	if err != nil {
+		t.Fatalf("Unexpected error: %v", err)
+	}
+	for i := 0; i < 110000; i++ {
+		if _, err := js.PublishAsync(fmt.Sprintf("FOO.%d", i), nil); err != nil {
+			t.Fatalf("Unexpected error: %v", err)
+		}
+	}
+	select {
+	case <-js.PublishAsyncComplete():
+	case <-time.After(5 * time.Second):
+		t.Fatal("PublishAsyncComplete timeout")
+	}
+
+	info, err := s.Info(context.Background(), jetstream.WithSubjectFilter("FOO.*"))
+	if err != nil {
+		t.Fatalf("Unexpected error: %v", err)
+	}
+	if len(info.State.Subjects) != 110000 {
+		t.Fatalf("Unexpected number of subjects; want: 110000; got: %d", len(info.State.Subjects))
+	}
+	cInfo := s.CachedInfo()
+	if len(cInfo.State.Subjects) != 0 {
+		t.Fatalf("Unexpected number of subjects; want: 0; got: %d", len(cInfo.State.Subjects))
+	}
+}
+
 func TestStreamCachedInfo(t *testing.T) {
 	srv := RunBasicJetStreamServer()
 	defer shutdownJSServerAndRemoveStorage(t, srv)