diff --git a/lib/compress.js b/lib/compress.js
index 245c3737b2f..eb932c7708d 100644
--- a/lib/compress.js
+++ b/lib/compress.js
@@ -14076,6 +14076,7 @@ Compressor.prototype.compress = function(node) {
                 var sym = def.orig[0];
                 if (sym instanceof AST_SymbolCatch) return;
                 body.push(make_node(AST_SimpleStatement, sym, { body: init_ref(compressor, flatten_var(sym)) }));
+                def.first_decl = null;
             });
             var defs = Object.create(null), syms = new Dictionary();
             if (simple_argnames && all(call.args, function(arg) {
diff --git a/test/compress/let.js b/test/compress/let.js
index 7a60e19592a..ba6c4bc74ae 100644
--- a/test/compress/let.js
+++ b/test/compress/let.js
@@ -2493,3 +2493,47 @@ issue_5756_3: {
     expect_stdout: "PASS"
     node_version: ">=4"
 }
+
+issue_5759: {
+    options = {
+        collapse_vars: true,
+        inline: true,
+        join_vars: true,
+        reduce_vars: true,
+        unused: true,
+    }
+    input: {
+        "use strict";
+        function f() {
+            for (var a in [ true ]) {
+                let b;
+                (function() {
+                    var c = void 0;
+                    b;
+                    console.log(c);
+                    var d = null;
+                    console.log(c);
+                })();
+            }
+        }
+        f();
+    }
+    expect: {
+        "use strict";
+        function f() {
+            for (var a in [ true ]) {
+                let b;
+                var c = c = void 0;
+                b;
+                console.log(c);
+                console.log(c);
+            }
+        }
+        f();
+    }
+    expect_stdout: [
+        "undefined",
+        "undefined",
+    ]
+    node_version: ">=4"
+}