diff --git a/packages/playwright-core/src/server/chromium/crPage.ts b/packages/playwright-core/src/server/chromium/crPage.ts
index 8150fe61cd8fc..34d1c53cd4236 100644
--- a/packages/playwright-core/src/server/chromium/crPage.ts
+++ b/packages/playwright-core/src/server/chromium/crPage.ts
@@ -510,28 +510,30 @@ class FrameSession {
           this._handleFrameTree(frameTree);
           this._addRendererListeners();
         }
-        const localFrames = this._isMainFrame() ? this._page.frames() : [this._page._frameManager.frame(this._targetId)!];
-        for (const frame of localFrames) {
-          // Note: frames might be removed before we send these.
-          this._client._sendMayFail('Page.createIsolatedWorld', {
-            frameId: frame._id,
-            grantUniveralAccess: true,
-            worldName: UTILITY_WORLD_NAME,
-          });
-          for (const binding of this._crPage._browserContext._pageBindings.values())
-            frame.evaluateExpression(binding.source).catch(e => {});
-          for (const source of this._crPage._browserContext.initScripts)
-            frame.evaluateExpression(source).catch(e => {});
-        }
+
         const isInitialEmptyPage = this._isMainFrame() && this._page.mainFrame().url() === ':';
         if (isInitialEmptyPage) {
-          // Ignore lifecycle events for the initial empty page. It is never the final page
+          // Ignore lifecycle events, worlds and bindings for the initial empty page. It is never the final page
           // hence we are going to get more lifecycle updates after the actual navigation has
           // started (even if the target url is about:blank).
           lifecycleEventsEnabled.catch(e => {}).then(() => {
             this._eventListeners.push(eventsHelper.addEventListener(this._client, 'Page.lifecycleEvent', event => this._onLifecycleEvent(event)));
           });
         } else {
+          const localFrames = this._isMainFrame() ? this._page.frames() : [this._page._frameManager.frame(this._targetId)!];
+          for (const frame of localFrames) {
+            // Note: frames might be removed before we send these.
+            this._client._sendMayFail('Page.createIsolatedWorld', {
+              frameId: frame._id,
+              grantUniveralAccess: true,
+              worldName: UTILITY_WORLD_NAME,
+            });
+            for (const binding of this._crPage._browserContext._pageBindings.values())
+              frame.evaluateExpression(binding.source).catch(e => {});
+            for (const source of this._crPage._browserContext.initScripts)
+              frame.evaluateExpression(source).catch(e => {});
+          }
+
           this._firstNonInitialNavigationCommittedFulfill();
           this._eventListeners.push(eventsHelper.addEventListener(this._client, 'Page.lifecycleEvent', event => this._onLifecycleEvent(event)));
         }
diff --git a/tests/page/page-add-init-script.spec.ts b/tests/page/page-add-init-script.spec.ts
index a24c1dad39a27..b2b7782ebac91 100644
--- a/tests/page/page-add-init-script.spec.ts
+++ b/tests/page/page-add-init-script.spec.ts
@@ -98,3 +98,14 @@ it('init script should run only once in iframe', async ({ page, server, browserN
     'init script: ' + (browserName === 'firefox' ? 'no url yet' : '/frames/frame.html'),
   ]);
 });
+
+it('init script should run only once in popup', async ({ page, browserName }) => {
+  await page.context().addInitScript(() => {
+    window['callCount'] = (window['callCount'] || 0) + 1;
+  });
+  const [popup] = await Promise.all([
+    page.waitForEvent('popup'),
+    page.evaluate(() => window.open('about:blank')),
+  ]);
+  expect(await popup.evaluate('callCount')).toEqual(1);
+});