diff --git a/app/code/Magento/SalesSequence/Model/ResourceModel/Meta.php b/app/code/Magento/SalesSequence/Model/ResourceModel/Meta.php
index 7a4aabea85680..8422123c0ca84 100644
--- a/app/code/Magento/SalesSequence/Model/ResourceModel/Meta.php
+++ b/app/code/Magento/SalesSequence/Model/ResourceModel/Meta.php
@@ -132,6 +132,7 @@ protected function _beforeSave(\Magento\Framework\Model\AbstractModel $object)
             || $object->getData('store_id') === null
             || !$object->getData('sequence_table')
         ) {
+            // phpcs:ignore Magento2.Exceptions.DirectThrow
             throw new Exception(__('Not enough arguments'));
         }
 
diff --git a/app/code/Magento/SalesSequence/Model/Sequence/DeleteByStore.php b/app/code/Magento/SalesSequence/Model/Sequence/DeleteByStore.php
new file mode 100644
index 0000000000000..e86cc8b1b2e6d
--- /dev/null
+++ b/app/code/Magento/SalesSequence/Model/Sequence/DeleteByStore.php
@@ -0,0 +1,117 @@
+<?php
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+declare(strict_types=1);
+
+namespace Magento\SalesSequence\Model\Sequence;
+
+use Magento\Framework\App\ResourceConnection as AppResource;
+use Magento\SalesSequence\Model\MetaFactory;
+use Magento\SalesSequence\Model\ResourceModel\Meta as ResourceMetadata;
+
+/**
+ * Delete Sequence by Store.
+ */
+class DeleteByStore
+{
+    /**
+     * @var ResourceMetadata
+     */
+    private $resourceMetadata;
+
+    /**
+     * @var MetaFactory
+     */
+    private $metaFactory;
+
+    /**
+     * @var AppResource
+     */
+    private $appResource;
+
+    /**
+     * @param ResourceMetadata $resourceMetadata
+     * @param MetaFactory $metaFactory
+     * @param AppResource $appResource
+     */
+    public function __construct(
+        ResourceMetadata $resourceMetadata,
+        MetaFactory $metaFactory,
+        AppResource $appResource
+    ) {
+        $this->resourceMetadata = $resourceMetadata;
+        $this->metaFactory = $metaFactory;
+        $this->appResource = $appResource;
+    }
+
+    /**
+     * Deletes all sequence linked entites
+     *
+     * @param int $storeId
+     * @return void
+     * @throws \Exception
+     */
+    public function execute($storeId): void
+    {
+        $metadataIds = $this->getMetadataIdsByStoreId($storeId);
+        $profileIds = $this->getProfileIdsByMetadataIds($metadataIds);
+
+        $this->appResource->getConnection()->delete(
+            $this->appResource->getTableName('sales_sequence_profile'),
+            ['profile_id IN (?)' => $profileIds]
+        );
+
+        foreach ($metadataIds as $metadataId) {
+            $metadata = $this->metaFactory->create();
+            $this->resourceMetadata->load($metadata, $metadataId);
+            if (!$metadata->getId()) {
+                continue;
+            }
+
+            $this->appResource->getConnection()->dropTable(
+                $metadata->getSequenceTable()
+            );
+            $this->resourceMetadata->delete($metadata);
+        }
+    }
+
+    /**
+     * Retrieves Metadata Ids by store id
+     *
+     * @param int $storeId
+     * @return int[]
+     */
+    private function getMetadataIdsByStoreId($storeId)
+    {
+        $connection = $this->appResource->getConnection();
+        $bind = ['store_id' => $storeId];
+        $select = $connection->select()->from(
+            $this->appResource->getTableName('sales_sequence_meta'),
+            ['meta_id']
+        )->where(
+            'store_id = :store_id'
+        );
+
+        return $connection->fetchCol($select, $bind);
+    }
+
+    /**
+     * Retrieves Profile Ids by metadata ids
+     *
+     * @param int[] $metadataIds
+     * @return int[]
+     */
+    private function getProfileIdsByMetadataIds(array $metadataIds)
+    {
+        $connection = $this->appResource->getConnection();
+        $select = $connection->select()
+            ->from(
+                $this->appResource->getTableName('sales_sequence_profile'),
+                ['profile_id']
+            )->where('meta_id IN (?)', $metadataIds);
+
+        return $connection->fetchCol($select);
+    }
+}
diff --git a/app/code/Magento/SalesSequence/Observer/SequenceRemovalObserver.php b/app/code/Magento/SalesSequence/Observer/SequenceRemovalObserver.php
new file mode 100644
index 0000000000000..c10ef80f6eb9b
--- /dev/null
+++ b/app/code/Magento/SalesSequence/Observer/SequenceRemovalObserver.php
@@ -0,0 +1,48 @@
+<?php
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+declare(strict_types=1);
+
+namespace Magento\SalesSequence\Observer;
+
+use Magento\Framework\Event\ObserverInterface;
+use Magento\Framework\Event\Observer as EventObserver;
+use Magento\SalesSequence\Model\Sequence\DeleteByStore;
+
+/**
+ * Observer for Sequence Removal.
+ */
+class SequenceRemovalObserver implements ObserverInterface
+{
+    /**
+     * @var DeleteByStore
+     */
+    private $deleteByStore;
+
+    /**
+     * @param DeleteByStore $deleteByStore
+     */
+    public function __construct(
+        DeleteByStore $deleteByStore
+    ) {
+        $this->deleteByStore = $deleteByStore;
+    }
+
+    /**
+     * Deletes all sequence linked entities.
+     *
+     * @param EventObserver $observer
+     * @return $this
+     * @throws \Magento\Framework\Exception\LocalizedException
+     */
+    public function execute(EventObserver $observer)
+    {
+        if ($store = $observer->getData('store')) {
+            $this->deleteByStore->execute($store->getId());
+        }
+
+        return $this;
+    }
+}
diff --git a/app/code/Magento/SalesSequence/Test/Unit/Model/Sequence/DeleteByStoreTest.php b/app/code/Magento/SalesSequence/Test/Unit/Model/Sequence/DeleteByStoreTest.php
new file mode 100644
index 0000000000000..17dbd6c37265f
--- /dev/null
+++ b/app/code/Magento/SalesSequence/Test/Unit/Model/Sequence/DeleteByStoreTest.php
@@ -0,0 +1,147 @@
+<?php
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+namespace Magento\SalesSequence\Test\Unit\Model\Sequence;
+
+use Magento\Framework\App\ResourceConnection;
+use Magento\Framework\DB\Adapter\AdapterInterface;
+use Magento\Framework\DB\Select;
+use Magento\Framework\TestFramework\Unit\Helper\ObjectManager;
+use Magento\SalesSequence\Model\Meta;
+use Magento\SalesSequence\Model\MetaFactory;
+use Magento\SalesSequence\Model\ResourceModel\Meta as ResourceMeta;
+use Magento\SalesSequence\Model\Sequence\DeleteByStore;
+use PHPUnit\Framework\MockObject\MockObject;
+use PHPUnit\Framework\TestCase;
+
+/**
+ * Test for \Magento\SalesSequence\Model\Sequence\DeleteByStore class.
+ */
+class DeleteByStoreTest extends TestCase
+{
+    /**
+     * @var DeleteByStore
+     */
+    private $deleteByStore;
+
+    /**
+     * @var ResourceMeta | MockObject
+     */
+    private $resourceSequenceMeta;
+
+    /**
+     * @var Meta | MockObject
+     */
+    private $meta;
+
+    /**
+     * @var MetaFactory | MockObject
+     */
+    private $metaFactory;
+
+    /**
+     * @var AdapterInterface | MockObject
+     */
+    private $connectionMock;
+
+    /**
+     * @var ResourceConnection | MockObject
+     */
+    private $resourceMock;
+
+    /**
+     * @var Select | MockObject
+     */
+    private $select;
+
+    protected function setUp()
+    {
+        $this->connectionMock = $this->getMockForAbstractClass(
+            AdapterInterface::class,
+            [],
+            '',
+            false,
+            false,
+            true,
+            ['delete', 'query']
+        );
+        $this->resourceSequenceMeta = $this->createPartialMock(
+            ResourceMeta::class,
+            ['load', 'delete']
+        );
+        $this->meta = $this->createPartialMock(
+            Meta::class,
+            ['getSequenceTable']
+        );
+        $this->resourceMock = $this->createMock(ResourceConnection::class);
+        $this->select = $this->createMock(Select::class);
+        $this->metaFactory = $this->createPartialMock(MetaFactory::class, ['create']);
+        $this->metaFactory->method('create')->willReturn($this->meta);
+
+        $helper = new ObjectManager($this);
+        $this->deleteByStore = $helper->getObject(
+            DeleteByStore::class,
+            [
+                'resourceMetadata' => $this->resourceSequenceMeta,
+                'metaFactory' => $this->metaFactory,
+                'appResource' => $this->resourceMock,
+            ]
+        );
+    }
+
+    /**
+     * @throws \Exception
+     * @SuppressWarnings(PHPMD.UnusedLocalVariable)
+     */
+    public function testExecute()
+    {
+        $profileTableName = 'sales_sequence_profile';
+        $storeId = 1;
+        $metadataIds = [1, 2];
+        $profileIds = [10, 11];
+        $this->resourceMock->method('getTableName')
+            ->willReturnCallback(
+                static function ($tableName) {
+                    return $tableName;
+                }
+            );
+        $this->resourceMock->method('getConnection')
+            ->willReturn($this->connectionMock);
+        $this->connectionMock
+            ->method('select')
+            ->willReturn($this->select);
+
+        $this->select->method('from')
+            ->willReturn($this->select);
+        $this->select->method('where')
+            ->willReturn($this->select);
+
+        $this->connectionMock->method('fetchCol')
+            ->willReturnCallback(
+                static function ($arg, $arg2) use ($metadataIds, $profileIds) {
+                    if (array_key_exists('store', $arg2)) {
+                        return $metadataIds;
+                    }
+
+                    return $profileIds;
+                }
+            );
+
+        $this->connectionMock->expects($this->once())
+            ->method('delete')
+            ->with($profileTableName, ['profile_id IN (?)' => $profileIds])
+            ->willReturn(2);
+        $this->resourceSequenceMeta
+            ->method('load')
+            ->willReturn($this->meta);
+        $this->connectionMock
+            ->method('dropTable')
+            ->willReturn(true);
+        $this->resourceSequenceMeta
+            ->method('delete')
+            ->willReturn($this->resourceSequenceMeta);
+        $this->deleteByStore->execute($storeId);
+    }
+}
diff --git a/app/code/Magento/SalesSequence/etc/events.xml b/app/code/Magento/SalesSequence/etc/events.xml
new file mode 100644
index 0000000000000..5bbde6ab188a5
--- /dev/null
+++ b/app/code/Magento/SalesSequence/etc/events.xml
@@ -0,0 +1,12 @@
+<?xml version="1.0"?>
+<!--
+/**
+ * Copyright © Magento, Inc. All rights reserved.
+ * See COPYING.txt for license details.
+ */
+-->
+<config xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:noNamespaceSchemaLocation="urn:magento:framework:Event/etc/events.xsd">
+    <event name="store_delete">
+        <observer name="magento_sequence" instance="Magento\SalesSequence\Observer\SequenceRemovalObserver" />
+    </event>
+</config>
diff --git a/dev/tests/integration/framework/Magento/TestFramework/Application.php b/dev/tests/integration/framework/Magento/TestFramework/Application.php
index 1bfc928f2916a..f0ce2e24545eb 100644
--- a/dev/tests/integration/framework/Magento/TestFramework/Application.php
+++ b/dev/tests/integration/framework/Magento/TestFramework/Application.php
@@ -558,7 +558,7 @@ private function copyAppConfigFiles()
             }
         }
     }
-    
+
     /**
      * Copies global configuration file from the tests folder (see TESTS_GLOBAL_CONFIG_FILE)
      *
diff --git a/dev/tests/integration/testsuite/Magento/Catalog/Model/Product/UrlTest.php b/dev/tests/integration/testsuite/Magento/Catalog/Model/Product/UrlTest.php
index ff2979150954e..451e19be28e5f 100644
--- a/dev/tests/integration/testsuite/Magento/Catalog/Model/Product/UrlTest.php
+++ b/dev/tests/integration/testsuite/Magento/Catalog/Model/Product/UrlTest.php
@@ -53,8 +53,8 @@ public function testGetUrlInStore()
      * @magentoConfigFixture fixturestore_store web/unsecure/base_url http://sample-second.com/
      * @magentoConfigFixture fixturestore_store web/unsecure/base_link_url http://sample-second.com/
      * @magentoDataFixture Magento/Catalog/_files/product_simple_multistore.php
-     * @magentoDbIsolation disabled
      * @dataProvider getUrlsWithSecondStoreProvider
+     * @magentoDbIsolation disabled
      * @magentoAppArea adminhtml
      */
     public function testGetUrlInStoreWithSecondStore($storeCode, $expectedProductUrl)
diff --git a/dev/tests/integration/testsuite/Magento/Store/Model/StoreTest.php b/dev/tests/integration/testsuite/Magento/Store/Model/StoreTest.php
index 00de5544d8fb7..58c7d1cba45fe 100644
--- a/dev/tests/integration/testsuite/Magento/Store/Model/StoreTest.php
+++ b/dev/tests/integration/testsuite/Magento/Store/Model/StoreTest.php
@@ -176,11 +176,13 @@ public function getBaseUrlDataProvider()
      */
     public function testGetBaseUrlInPub()
     {
-        \Magento\TestFramework\Helper\Bootstrap::getInstance()->reinitialize([
-            Bootstrap::INIT_PARAM_FILESYSTEM_DIR_PATHS => [
-                DirectoryList::PUB => [DirectoryList::URL_PATH => ''],
-            ],
-        ]);
+        \Magento\TestFramework\Helper\Bootstrap::getInstance()->reinitialize(
+            [
+                Bootstrap::INIT_PARAM_FILESYSTEM_DIR_PATHS => [
+                    DirectoryList::PUB => [DirectoryList::URL_PATH => ''],
+                ],
+            ]
+        );
 
         $this->model = $this->_getStoreModel();
         $this->model->load('default');
@@ -276,14 +278,14 @@ public function testIsCanDelete()
 
     /**
      * @magentoDataFixture Magento/Store/_files/core_second_third_fixturestore.php
-     * @magentoDataFixture Magento/Catalog/_files/product_simple.php
-     * @magentoDbIsolation disabled
+     * @magentoDataFixture Magento/Catalog/_files/products.php
+     * @magentoAppIsolation enabled
      */
     public function testGetCurrentUrl()
     {
         $objectManager = \Magento\TestFramework\Helper\Bootstrap::getObjectManager();
         $objectManager->get(\Magento\Framework\App\Config\MutableScopeConfigInterface::class)
-        ->setValue('web/url/use_store', true, ScopeInterface::SCOPE_STORE, 'secondstore');
+            ->setValue('web/url/use_store', true, ScopeInterface::SCOPE_STORE, 'secondstore');
 
         $this->model->load('admin');
         $this->model
@@ -316,9 +318,10 @@ public function testGetCurrentUrl()
     }
 
     /**
-     * @magentoDataFixture Magento/Store/_files/second_store.php
-     * @magentoDataFixture Magento/Catalog/_files/category_product.php
-     * @magentoDbIsolation disabled
+     * @magentoDataFixture Magento/Store/_files/core_second_third_fixturestore.php
+     * @magentoDataFixture Magento/Catalog/_files/products.php
+     * @magentoAppIsolation enabled
+     * @magentoDbIsolation enabled
      */
     public function testGetCurrentUrlWithUseStoreInUrlFalse()
     {
@@ -327,34 +330,34 @@ public function testGetCurrentUrlWithUseStoreInUrlFalse()
             ->setValue('web/url/use_store', false, ScopeInterface::SCOPE_STORE, 'default');
 
         /** @var \Magento\Store\Model\Store $secondStore */
-        $secondStore = $objectManager->get(StoreRepositoryInterface::class)->get('fixture_second_store');
+        $secondStore = $objectManager->get(StoreRepositoryInterface::class)->get('secondstore');
 
         /** @var \Magento\Catalog\Model\ProductRepository $productRepository */
         $productRepository = $objectManager->create(ProductRepository::class);
-        $product = $productRepository->get('simple333');
+        $product = $productRepository->get('simple');
 
         $product->setStoreId($secondStore->getId());
         $url = $product->getUrlInStore();
 
         /** @var \Magento\Catalog\Model\CategoryRepository $categoryRepository */
         $categoryRepository = $objectManager->get(\Magento\Catalog\Model\CategoryRepository::class);
-        $category = $categoryRepository->get(333, $secondStore->getStoreId());
+        $category = $categoryRepository->get(2, $secondStore->getStoreId());
 
         $this->assertEquals(
-            $secondStore->getBaseUrl() . 'catalog/category/view/s/category-1/id/333/',
+            $secondStore->getBaseUrl() . 'catalog/category/view/s/default-category/id/2/',
             $category->getUrl()
         );
         $this->assertEquals(
             $secondStore->getBaseUrl() .
-            'catalog/product/view/id/333/s/simple-product-three/?___store=fixture_second_store',
+            'catalog/product/view/id/1/s/simple-product/?___store=secondstore',
             $url
         );
         $this->assertEquals(
-            $secondStore->getBaseUrl() . '?___store=fixture_second_store&___from_store=default',
+            $secondStore->getBaseUrl() . '?___store=secondstore&___from_store=default',
             $secondStore->getCurrentUrl()
         );
         $this->assertEquals(
-            $secondStore->getBaseUrl() . '?___store=fixture_second_store',
+            $secondStore->getBaseUrl() . '?___store=secondstore',
             $secondStore->getCurrentUrl(false)
         );
     }
@@ -366,14 +369,16 @@ public function testGetCurrentUrlWithUseStoreInUrlFalse()
      */
     public function testCRUD()
     {
-        $this->model->setData([
-            'code' => 'test',
-            'website_id' => 1,
-            'group_id' => 1,
-            'name' => 'test name',
-            'sort_order' => 0,
-            'is_active' => 1,
-        ]);
+        $this->model->setData(
+            [
+                'code' => 'test',
+                'website_id' => 1,
+                'group_id' => 1,
+                'name' => 'test name',
+                'sort_order' => 0,
+                'is_active' => 1,
+            ]
+        );
         $crud = new \Magento\TestFramework\Entity(
             $this->model,
             ['name' => 'new name'],
@@ -446,8 +451,8 @@ public function testIsUseStoreInUrl($storeInUrl, $disableStoreInUrl, $expectedRe
     }
 
     /**
-     * @see self::testIsUseStoreInUrl;
      * @return array
+     * @see self::testIsUseStoreInUrl;
      */
     public function isUseStoreInUrlDataProvider()
     {