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polyclonal documentation

polyclonal is a Python package for modeling mutational escape from polyclonal antibodies using deep mutational scanning data.

It is written by the Bloom lab.

See Yu et al (2022) for an explanation of the approach implemented in polyclonal.

See below for information and examples of how to use this package.

Contents

.. toctree::
   :hidden:

   self

.. toctree::
   :maxdepth: 1

   installation
   biophysical_model
   visualize_RBD
   simulate_RBD
   fit_RBD
   fit_2epitope
   regularization
   RBD_average
   real_LyCoV1404
   reference_site_numbering
   real_cocktail
   specify_epitopes
   expt_design
   optimization
   partition_function
   polyclonal
   package_index
   acknowledgments