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variants from primary tumors and metastasis tumors without normal controls #45

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qindan2008 opened this issue Oct 28, 2020 · 0 comments
Open

variants from primary tumors and metastasis tumors without normal controls #45

qindan2008 opened this issue Oct 28, 2020 · 0 comments

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@qindan2008
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Hello,
I have 10 pairs of samples. They're paired primary and metastasis tumors, but none of them have normal controls.
Can variants called by mutect2 or other snp callers be used by SciClone and ClonEvol ? The variants are just mixtures of germline and somatic mutations.
I just want to know about tumor clone and evolution.

Thank you very much.
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@qindan2008