diff --git a/hail/scripts/assert_pypi_has_room.py b/hail/scripts/assert_pypi_has_room.py
new file mode 100644
index 00000000000..edf50539a9c
--- /dev/null
+++ b/hail/scripts/assert_pypi_has_room.py
@@ -0,0 +1,11 @@
+import os
+
+wheel_size = os.path.getsize(os.environ["WHEEL"])
+pypi_used_storage = int(os.environ["PYPI_USED_STORAGE"])
+
+print(f'Wheel size: {wheel_size / 1024 / 1024:.0f}MiB. PyPI used storage: {pypi_used_storage / 1024 / 1024:.0f}MiB.')
+
+if wheel_size + pypi_used_storage > 10 * 1024 * 1024 * 1024:
+    print('Insufficient space available at PyPI.')
+    exit(1)
+print('Sufficient space is available at PyPI.')
diff --git a/hail/scripts/deploy.sh b/hail/scripts/deploy.sh
index 1446bee5a87..f29edfef12d 100755
--- a/hail/scripts/deploy.sh
+++ b/hail/scripts/deploy.sh
@@ -2,6 +2,8 @@
 
 set -ex
 
+SCRIPT_DIR=$( cd -- "$( dirname -- "${BASH_SOURCE[0]}" )" &> /dev/null && pwd )
+
 retry() {
     "$@" ||
         (sleep 2 && "$@") ||
@@ -59,6 +61,9 @@ then
     exit 1
 fi
 
+export PYPI_USED_STORAGE=$(curl https://pypi.org/pypi/hail/json | jq '[.releases[][].size ]| add')
+python3 $SCRIPT_DIR/assert_pypi_has_room.py
+
 # push git tag
 git tag $HAIL_PIP_VERSION -m "Hail version $HAIL_PIP_VERSION."
 git push origin $HAIL_PIP_VERSION