diff --git a/src/list/inner/CascaderItem.tsx b/src/list/inner/CascaderItem.tsx
index 435f97a2dd..381b55c6bd 100644
--- a/src/list/inner/CascaderItem.tsx
+++ b/src/list/inner/CascaderItem.tsx
@@ -11,6 +11,7 @@ import List from '../List';
 import { convertChildrenToData, generateSelectParent, generateString } from '../util';
 import { ListContext } from '../context';
 import { BaseItemProps } from '..';
+import TriggerContext from '../../popover/context';
 
 const CascaderItem: React.ForwardRefRenderFunction<
   HTMLLIElement,
@@ -23,6 +24,7 @@ const CascaderItem: React.ForwardRefRenderFunction<
   const popoverClassName = `${prefixCls}--content`;
   /** context */
   const context = useContext(ListContext);
+  const popoverContext = useContext(TriggerContext);
   const { disabled: contextDisabled, selectParent, onClick: contextOnClick, setOptions } = context;
   /** end */
   const childSelectPrent = generateSelectParent(label, value, selectParent);
@@ -91,19 +93,21 @@ const CascaderItem: React.ForwardRefRenderFunction<
     if (!isEmpty(childrens) || React.isValidElement(children)) {
       return (
         <div className={prefixClsItem}>
-          <Popover
-            placement="rightTop"
-            overlayClassName={popoverClassName}
-            // document click contains node
-            getContainer={() => document.body}
-            content={content()}
-            strategy={strategy}
-            distoryOnHide
-            delay={200}
-            offset={[0, 12]}
-          >
-            {element}
-          </Popover>
+          <TriggerContext.Provider value={popoverContext}>
+            <Popover
+                placement="rightTop"
+                overlayClassName={popoverClassName}
+                // document click contains node
+                getContainer={() => document.body}
+                content={content()}
+                strategy={strategy}
+                distoryOnHide
+                delay={200}
+                offset={[0, 12]}
+              >
+                {element}
+              </Popover>
+          </TriggerContext.Provider>
         </div>
       );
     }
diff --git a/src/popover/Popover.tsx b/src/popover/Popover.tsx
index 1682d72348..34253eaf70 100644
--- a/src/popover/Popover.tsx
+++ b/src/popover/Popover.tsx
@@ -1,4 +1,4 @@
-import React, { useState, useMemo, useCallback, useRef, useLayoutEffect, useEffect } from 'react';
+import React, { useState, useMemo, useCallback, useRef, useLayoutEffect, useEffect, useContext } from 'react';
 import classNames from 'classnames';
 import { debounce, isFunction, isNil, omit } from 'lodash';
 import ReactDOM from 'react-dom';
@@ -8,6 +8,7 @@ import { PopoverProps } from './interface';
 import { composeRef, supportRef } from '../utils/composeRef';
 import useControlledState from '../utils/hooks/useControlledState';
 import usePop from './usePop';
+import TriggerContext from './context';
 
 const Popover = (props: PopoverProps) => {
   const {
@@ -43,7 +44,10 @@ const Popover = (props: PopoverProps) => {
   const [referenceElement, setReferenceELement] = useState<null | HTMLElement>(null);
   const [popperElement, setPopperElement] = useState<null | HTMLElement>(null);
   const arrowElement = useRef<HTMLDivElement | null>(null);
-
+  const context = useContext(TriggerContext);
+  const hasPopupMouseDown = useRef<boolean>(false);
+  const mouseDownTimeout = useRef<any>(undefined);
+  // const
   useEffect(() => {
     if (!visible) overContentRef.current = false;
   }, [visible]);
@@ -120,11 +124,32 @@ const Popover = (props: PopoverProps) => {
     },
     [disabled, enterable, setVisible, onVisibleChange, update]
   );
+
+  // ============ nest popover on Document click close ============
+  const onPopupMouseDown = (event: React.MouseEvent<HTMLElement, MouseEvent>) => {
+    hasPopupMouseDown.current = true;
+
+    clearTimeout(mouseDownTimeout.current);
+    mouseDownTimeout.current = window.setTimeout(() => {
+      hasPopupMouseDown.current = false;
+    }, 0);
+
+    if (context) {
+      context?.onPopupMouseDown(event);
+    }
+  };
+
+  const triggerContextValue = { onPopupMouseDown };
+
   const onDocumentClick = useCallback(
     (event: MouseEvent) => {
       const { target } = event;
       if (isFunction(referenceElement?.contains) && isFunction(popperElement?.contains)) {
-        if (!referenceElement?.contains(target as Node) && !popperElement?.contains(target as Node)) {
+        if (
+          !referenceElement?.contains(target as Node) &&
+          !popperElement?.contains(target as Node) &&
+          !hasPopupMouseDown.current
+        ) {
           updateVisible(false);
         }
       }
@@ -139,6 +164,8 @@ const Popover = (props: PopoverProps) => {
     };
   }, [onDocumentClick]);
 
+  // ============ end ============
+
   const isClickToShow = useMemo(() => trigger.indexOf('click') !== -1, [trigger]);
 
   const isHoverToShow = useMemo(() => trigger.indexOf('hover') !== -1, [trigger]);
@@ -224,6 +251,7 @@ const Popover = (props: PopoverProps) => {
       style={{ ...(overlayStyle || {}), ...styles.popper }}
       onMouseEnter={onContentMouseEnter}
       onMouseLeave={onContentMouseLeave}
+      onMouseDownCapture={(e) => onPopupMouseDown(e)}
       onClick={onContentClick}
       role="none"
       {...omit(rest, 'arrowPointAtCenter')}
@@ -257,6 +285,7 @@ const Popover = (props: PopoverProps) => {
     cloneProps.ref = composeRef(setReferenceELement, (child as any).ref);
     triggerNode = React.cloneElement(child as React.ReactElement, cloneProps);
   }
+
   const container = useMemo(() => {
     if (isFunction(getContainer) && !isNil(referenceElement)) {
       return getContainer(referenceElement);
@@ -277,8 +306,10 @@ const Popover = (props: PopoverProps) => {
   );
   return (
     <>
-      {triggerNode}
-      {distoryOnHide ? visible && renderContent : renderContent}
+      <TriggerContext.Provider value={triggerContextValue}>
+        {triggerNode}
+        {distoryOnHide ? visible && renderContent : renderContent}
+      </TriggerContext.Provider>
     </>
   );
 };
diff --git a/src/popover/context.ts b/src/popover/context.ts
new file mode 100644
index 0000000000..632b4cbe50
--- /dev/null
+++ b/src/popover/context.ts
@@ -0,0 +1,9 @@
+import * as React from 'react';
+
+interface TriggerContextProps {
+  onPopupMouseDown: React.MouseEventHandler<HTMLElement>;
+}
+
+const TriggerContext = React.createContext<TriggerContextProps | null>(null);
+
+export default TriggerContext;