diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index 106b452abd3..88e217b547e 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -32,14 +32,14 @@ jobs:
     - name: Cache PyPI
       uses: actions/cache@v2
       with:
-        key: pip-lint-${{ hashFiles('requirements/*.txt') }}
+        key: pip-lint-${{ hashFiles('requirements/pinned/*.txt') }}
         path: ~/.cache/pip
         restore-keys: |
             pip-lint-
     - name: Install dependencies
       uses: py-actions/py-dependency-install@v2
       with:
-        path: requirements/lint.txt
+        path: requirements/pinned/linux-lint.txt
     - name: Pre-Commit hooks
       uses: pre-commit/action@v2.0.0
     - name: Install itself
@@ -53,7 +53,7 @@ jobs:
     - name: Install spell checker
       run: |
         sudo apt install libenchant-dev
-        pip install -r requirements/doc-spelling.txt
+        pip install -r requirements/pinned/linux-3.8-doc-spelling.txt
     - name: Run docs spelling
       run: |
         # towncrier --yes  # uncomment me after publishing a release
@@ -111,7 +111,7 @@ jobs:
     - name: Cache PyPI
       uses: actions/cache@v2
       with:
-        key: pip-ci-${{ runner.os }}-${{ matrix.pyver }}-${{ matrix.no-extensions }}-${{ hashFiles('requirements/*.txt') }}
+        key: pip-ci-${{ runner.os }}-${{ matrix.pyver }}-${{ matrix.no-extensions }}-${{ hashFiles('requirements/pinned/*.txt') }}
         path: ${{ steps.pip-cache.outputs.dir }}
         restore-keys: |
             pip-ci-${{ runner.os }}-${{ matrix.pyver }}-${{ matrix.no-extensions }}-
diff --git a/.pre-commit-config.yaml b/.pre-commit-config.yaml
index f1688c3dcb4..94fd2ea76d0 100644
--- a/.pre-commit-config.yaml
+++ b/.pre-commit-config.yaml
@@ -31,7 +31,7 @@ repos:
       ^docs/[^/]*\.svg$
   - id: requirements-txt-fixer
     exclude: >-
-      ^requirements/dev.txt$
+      ^requirements/pinned/.*\.txt$
   - id: trailing-whitespace
   - id: file-contents-sorter
     files: |
diff --git a/CHANGES/5486.misc b/CHANGES/5486.misc
new file mode 100644
index 00000000000..bc8fa84a4e3
--- /dev/null
+++ b/CHANGES/5486.misc
@@ -0,0 +1 @@
+Complete pip-tools setup.
diff --git a/Makefile b/Makefile
index 6a617042960..c72dd3fe584 100644
--- a/Makefile
+++ b/Makefile
@@ -7,9 +7,10 @@ CYS := $(wildcard aiohttp/*.pyx) $(wildcard aiohttp/*.pyi)  $(wildcard aiohttp/*
 PYXS := $(wildcard aiohttp/*.pyx)
 CS := $(wildcard aiohttp/*.c)
 PYS := $(wildcard aiohttp/*.py)
-REQS := $(wildcard requirements/*.txt)
+REQS := $(wildcard requirements/pinned/*.txt)
 ALLS := $(sort $(CYS) $(CS) $(PYS) $(REQS))
 
+
 .PHONY: all
 all: test
 
@@ -45,9 +46,11 @@ endif
 # Enumerate intermediate files to don't remove them automatically.
 .SECONDARY: $(call to-hash,$(ALLS))
 
+.update-pip:
+	@pip install -U 'pip'
 
-.install-cython: $(call to-hash,requirements/cython.txt)
-	pip install -r requirements/cython.txt
+.install-cython: .update-pip $(call to-hash,requirements/pinned/*cython.txt)
+	@python tools/deps.py install cython
 	@touch .install-cython
 
 aiohttp/_find_header.c: $(call to-hash,aiohttp/hdrs.py ./tools/gen.py)
@@ -62,7 +65,7 @@ aiohttp/%.c: aiohttp/%.pyx $(call to-hash,$(CYS)) aiohttp/_find_header.c
 cythonize: .install-cython $(PYXS:.pyx=.c)
 
 .install-deps: .install-cython $(PYXS:.pyx=.c) $(call to-hash,$(CYS) $(REQS))
-	pip install -r requirements/dev.txt
+	@python tools/deps.py install dev
 	@touch .install-deps
 
 .PHONY: lint
@@ -135,17 +138,14 @@ doc:
 doc-spelling:
 	@make -C docs spelling SPHINXOPTS="-W -E"
 
-.update-pip:
-	@pip install -U 'pip'
-
 .PHONY: compile-deps
 compile-deps: .update-pip
 	@pip install pip-tools
-	@pip-compile --allow-unsafe -q requirements/dev.in
+	@python tools/deps.py compile
 
 .PHONY: install
 install: .update-pip
-	@pip install -r requirements/dev.in -c requirements/dev.txt
+	@python tools/deps.py install dev
 
 .PHONY: install-dev
 install-dev: .develop
diff --git a/requirements/cython.txt b/requirements/cython.in
similarity index 100%
rename from requirements/cython.txt
rename to requirements/cython.in
diff --git a/requirements/dev.in b/requirements/dev.in
index fc7aee6945c..c5cb20f7102 100644
--- a/requirements/dev.in
+++ b/requirements/dev.in
@@ -1,4 +1,4 @@
--r lint.txt
+-r lint.in
 -r test.txt
 -r doc.txt
 cherry_picker==1.3.2; python_version>="3.6"
diff --git a/requirements/dev.txt b/requirements/dev.txt
deleted file mode 100644
index 6c3e3f33d68..00000000000
--- a/requirements/dev.txt
+++ /dev/null
@@ -1,252 +0,0 @@
-#
-# This file is autogenerated by pip-compile
-# To update, run:
-#
-#    pip-compile --allow-unsafe requirements/dev.in
-#
-aiodns==2.0.0 ; sys_platform == "linux" or sys_platform == "darwin" and python_version >= "3.7"
-    # via -r requirements/base.txt
-aiohttp-theme==0.1.6
-    # via -r requirements/doc.txt
-aiosignal==1.1.2
-    # via -r requirements/base.txt
-alabaster==0.7.12
-    # via sphinx
-appdirs==1.4.4
-    # via
-    #   black
-    #   virtualenv
-async-generator==1.10
-    # via -r requirements/base.txt
-async-timeout==4.0.0a3
-    # via -r requirements/base.txt
-attrs==20.3.0
-    # via
-    #   -r requirements/base.txt
-    #   flake8-pyi
-    #   pytest
-babel==2.9.0
-    # via sphinx
-black==20.8b1 ; implementation_name == "cpython"
-    # via -r requirements/lint.txt
-blockdiag==2.0.1
-    # via sphinxcontrib-blockdiag
-brotli==1.0.9
-    # via -r requirements/base.txt
-cchardet==2.1.7
-    # via -r requirements/base.txt
-certifi==2020.12.5
-    # via requests
-cffi==1.14.4
-    # via
-    #   cryptography
-    #   pycares
-cfgv==3.2.0
-    # via pre-commit
-chardet==4.0.0
-    # via
-    #   -r requirements/base.txt
-    #   requests
-cherry_picker==1.3.2 ; python_version >= "3.6"
-    # via -r requirements/dev.in
-click==7.1.2
-    # via
-    #   black
-    #   cherry-picker
-    #   towncrier
-coverage==5.3.1
-    # via
-    #   -r requirements/test.txt
-    #   pytest-cov
-cryptography==3.3.1
-    # via
-    #   pyjwt
-    #   trustme
-distlib==0.3.1
-    # via virtualenv
-docutils==0.16
-    # via sphinx
-filelock==3.0.12
-    # via virtualenv
-flake8-pyi==20.10.0
-    # via -r requirements/lint.txt
-flake8==3.8.4
-    # via
-    #   -r requirements/lint.txt
-    #   flake8-pyi
-freezegun==1.0.0
-    # via -r requirements/test.txt
-frozenlist==1.1.1
-    # via
-    #   -r requirements/base.txt
-    #   aiosignal
-funcparserlib==0.3.6
-    # via blockdiag
-gidgethub==5.0.0
-    # via cherry-picker
-gunicorn==20.0.4
-    # via -r requirements/base.txt
-identify==1.5.12
-    # via pre-commit
-idna==2.10
-    # via
-    #   requests
-    #   trustme
-    #   yarl
-imagesize==1.2.0
-    # via sphinx
-incremental==17.5.0
-    # via towncrier
-iniconfig==1.1.1
-    # via pytest
-isort==5.6.4
-    # via -r requirements/lint.txt
-jinja2==2.11.2
-    # via
-    #   sphinx
-    #   towncrier
-markupsafe==1.1.1
-    # via jinja2
-mccabe==0.6.1
-    # via flake8
-multidict==5.1.0
-    # via
-    #   -r requirements/multidict.txt
-    #   yarl
-mypy-extensions==0.4.3 ; implementation_name == "cpython"
-    # via
-    #   -r requirements/test.txt
-    #   black
-    #   mypy
-mypy==0.790 ; implementation_name == "cpython"
-    # via
-    #   -r requirements/lint.txt
-    #   -r requirements/test.txt
-nodeenv==1.5.0
-    # via pre-commit
-packaging==20.8
-    # via
-    #   pytest
-    #   sphinx
-pathspec==0.8.1
-    # via black
-pillow==8.1.0
-    # via blockdiag
-pluggy==0.13.1
-    # via pytest
-pre-commit==2.9.3
-    # via -r requirements/lint.txt
-py==1.10.0
-    # via pytest
-pycares==3.1.1
-    # via aiodns
-pycodestyle==2.6.0
-    # via flake8
-pycparser==2.20
-    # via cffi
-pyflakes==2.2.0
-    # via
-    #   flake8
-    #   flake8-pyi
-pygments==2.8.0
-    # via
-    #   -r requirements/doc.txt
-    #   sphinx
-pyjwt[crypto]==2.0.0
-    # via gidgethub
-pyparsing==2.4.7
-    # via packaging
-pytest-cov==2.10.1
-    # via -r requirements/test.txt
-pytest-mock==3.5.1
-    # via -r requirements/test.txt
-pytest==6.1.2
-    # via
-    #   -r requirements/lint.txt
-    #   -r requirements/test.txt
-    #   pytest-cov
-    #   pytest-mock
-python-dateutil==2.8.1
-    # via freezegun
-pytz==2020.5
-    # via babel
-pyyaml==5.3.1
-    # via pre-commit
-re-assert==1.1.0
-    # via -r requirements/test.txt
-regex==2020.11.13
-    # via
-    #   black
-    #   re-assert
-requests==2.25.1
-    # via
-    #   cherry-picker
-    #   sphinx
-setuptools-git==1.2
-    # via -r requirements/test.txt
-six==1.15.0
-    # via
-    #   cryptography
-    #   python-dateutil
-    #   virtualenv
-snowballstemmer==2.0.0
-    # via sphinx
-sphinx==3.5.0
-    # via
-    #   -r requirements/doc.txt
-    #   sphinxcontrib-asyncio
-    #   sphinxcontrib-blockdiag
-sphinxcontrib-applehelp==1.0.2
-    # via sphinx
-sphinxcontrib-asyncio==0.3.0
-    # via -r requirements/doc.txt
-sphinxcontrib-blockdiag==2.0.0
-    # via -r requirements/doc.txt
-sphinxcontrib-devhelp==1.0.2
-    # via sphinx
-sphinxcontrib-htmlhelp==1.0.3
-    # via sphinx
-sphinxcontrib-jsmath==1.0.1
-    # via sphinx
-sphinxcontrib-qthelp==1.0.3
-    # via sphinx
-sphinxcontrib-serializinghtml==1.1.4
-    # via sphinx
-toml==0.10.2
-    # via
-    #   black
-    #   cherry-picker
-    #   pre-commit
-    #   pytest
-    #   towncrier
-towncrier==19.2.0
-    # via -r requirements/doc.txt
-trustme==0.7.0 ; platform_machine != "i686"
-    # via -r requirements/test.txt
-typed-ast==1.4.2
-    # via
-    #   black
-    #   mypy
-typing-extensions==3.7.4.3
-    # via
-    #   -r requirements/base.txt
-    #   async-timeout
-    #   black
-    #   mypy
-uritemplate==3.0.1
-    # via gidgethub
-urllib3==1.26.2
-    # via requests
-virtualenv==20.3.1
-    # via pre-commit
-webcolors==1.11.1
-    # via blockdiag
-yarl==1.6.3
-    # via -r requirements/base.txt
-
-# The following packages are considered to be unsafe in a requirements file:
-setuptools==51.3.1
-    # via
-    #   blockdiag
-    #   gunicorn
-    #   sphinx
diff --git a/requirements/doc-spelling.txt b/requirements/doc-spelling.in
similarity index 100%
rename from requirements/doc-spelling.txt
rename to requirements/doc-spelling.in
diff --git a/requirements/lint.txt b/requirements/lint.in
similarity index 71%
rename from requirements/lint.txt
rename to requirements/lint.in
index 71ddfd1f8b0..ccfe30aac8c 100644
--- a/requirements/lint.txt
+++ b/requirements/lint.in
@@ -1,7 +1,8 @@
 black==20.8b1; implementation_name=="cpython"
 flake8==3.8.4
 flake8-pyi==20.10.0
-isort==5.6.4
+importlib-metadata==3.7.0; python_version < "3.8"
+isort==5.7.0
 mypy==0.790; implementation_name=="cpython"
 pre-commit==2.9.3
 pytest==6.1.2
diff --git a/tools/deps.py b/tools/deps.py
new file mode 100755
index 00000000000..e0d8a45044d
--- /dev/null
+++ b/tools/deps.py
@@ -0,0 +1,101 @@
+#!/usr/bin/env python3
+
+import argparse
+import collections
+import hashlib
+import os
+import pathlib
+import platform
+import subprocess
+import sys
+
+PLATFORM_NAME = sys.platform if platform.python_implementation() != "PyPy" else "pypy"
+ROOT = pathlib.Path(__file__).parent.parent
+REQ_FOLDER = ROOT / "requirements"
+PIN_FOLDER = REQ_FOLDER / "pinned"
+
+
+def txt_file_name(in_file_name):
+    components = (
+        PLATFORM_NAME,
+        f"{sys.version_info.major}.{sys.version_info.minor}",
+        in_file_name,
+    )
+    txt_name = f"{'-'.join(components)}.txt"
+    return PIN_FOLDER / txt_name
+
+
+def compile_dependencies():
+    for in_file in REQ_FOLDER.glob("*.in"):
+        output_file = txt_file_name(in_file.stem)
+
+        subprocess.call(
+            (
+                "pip-compile",
+                "--allow-unsafe",
+                "--generate-hashes",
+                "--no-header",
+                "--no-annotate",
+                "--quiet",
+                "--output-file",
+                str(output_file),
+                str(in_file),
+            )
+        )
+
+
+def install_dependencies(in_name):
+    txt_file = txt_file_name(in_name)
+
+    subprocess.call(
+        (
+            "pip",
+            "install",
+            "--require-hashes",
+            "-r",
+            str(txt_file),
+        )
+    )
+
+
+def replace_duplicates_with_symlinks():
+    hash_to_file = collections.defaultdict(list)
+
+    orig_dir = os.getcwd()
+    os.chdir(PIN_FOLDER)
+    try:
+        for txt_fname in pathlib.Path(".").glob("*.txt"):
+            if not txt_fname.is_symlink():
+                with open(txt_fname, "rb") as f:
+                    digest = hashlib.sha1(f.read()).hexdigest()
+                    hash_to_file[digest].append(txt_fname)
+
+        for digest, files in hash_to_file.items():
+            if len(files) > 1:
+                base_file, *other_files = files
+                for other_file in other_files:
+                    os.unlink(other_file)
+                    os.symlink(base_file, other_file)
+    finally:
+        os.chdir(orig_dir)
+
+
+if __name__ == "__main__":
+    parser = argparse.ArgumentParser()
+    subparsers = parser.add_subparsers(dest="cmd", help="sub-command help")
+
+    install_parser = subparsers.add_parser("install", help="install dependencies")
+    compile_parser = subparsers.add_parser("compile", help="compile dependencies")
+    remove_duplicates = subparsers.add_parser(
+        "rdup", help="remove duplicate .txt files"
+    )
+
+    install_parser.add_argument("file", type=str, help="dep to install", default="dev")
+
+    args = parser.parse_args()
+    if args.cmd == "install":
+        install_dependencies(args.file)
+    elif args.cmd == "compile":
+        compile_dependencies()
+    elif args.cmd == "rdup":
+        replace_duplicates_with_symlinks()