diff --git a/jsonnet/mimir-mixin/alerts/alerts.libsonnet b/jsonnet/mimir-mixin/alerts/alerts.libsonnet
index a0e286ccea8..9eefe7f822e 100644
--- a/jsonnet/mimir-mixin/alerts/alerts.libsonnet
+++ b/jsonnet/mimir-mixin/alerts/alerts.libsonnet
@@ -13,7 +13,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'There are {{ printf "%f" $value }} unhealthy ingester(s).',
+            message: 'Cortex cluster %(alert_aggregation_variables)s has {{ printf "%%f" $value }} unhealthy ingester(s).' % $._config,
           },
         },
         {
@@ -35,8 +35,8 @@
           },
           annotations: {
             message: |||
-              {{ $labels.job }} {{ $labels.route }} is experiencing {{ printf "%.2f" $value }}% errors.
-            |||,
+              The route {{ $labels.route }} in %(alert_aggregation_variables)s is experiencing {{ printf "%%.2f" $value }}%% errors.
+            ||| % $._config,
           },
         },
         {
@@ -98,8 +98,8 @@
           },
           annotations: {
             message: |||
-              Incorrect results for {{ printf "%.2f" $value }}% of queries.
-            |||,
+              The Cortex cluster %(alert_aggregation_variables)s is experiencing {{ printf "%%.2f" $value }}%% incorrect query results.
+            ||| % $._config,
           },
         },
         {
@@ -113,8 +113,8 @@
           },
           annotations: {
             message: |||
-              An inconsistent runtime config file is used across cluster {{ $labels.job }}.
-            |||,
+              An inconsistent runtime config file is used across cluster %(alert_aggregation_variables)s.
+            ||| % $._config,
           },
         },
         {
@@ -145,8 +145,8 @@
           },
           annotations: {
             message: |||
-              There are {{ $value }} queued up queries in query-frontend.
-            |||,
+              There are {{ $value }} queued up queries in %(alert_aggregation_variables)s query-frontend.
+            ||| % $._config,
           },
         },
         {
@@ -160,8 +160,8 @@
           },
           annotations: {
             message: |||
-              There are {{ $value }} queued up queries in query-scheduler.
-            |||,
+              There are {{ $value }} queued up queries in %(alert_aggregation_variables)s query-scheduler.
+            ||| % $._config,
           },
         },
         {
@@ -178,8 +178,8 @@
           },
           annotations: {
             message: |||
-              Memcached {{ $labels.name }} used by Cortex in {{ $labels.namespace }} is experiencing {{ printf "%.2f" $value }}% errors for {{ $labels.operation }} operation.
-            |||,
+              Memcached {{ $labels.name }} used by Cortex %(alert_aggregation_variables)s is experiencing {{ printf "%%.2f" $value }}%% errors for {{ $labels.operation }} operation.
+            ||| % $._config,
           },
         },
         {
@@ -430,8 +430,8 @@
           },
           annotations: {
             message: |||
-              Chunk memcached cluster is too small, should be at least {{ printf "%.2f" $value }}GB.
-            |||,
+              Chunk memcached cluster in %(alert_aggregation_variables)s is too small, should be at least {{ printf "%%.2f" $value }}GB.
+            ||| % $._config,
           },
         },
         {
@@ -448,8 +448,8 @@
           },
           annotations: {
             message: |||
-              The number of in-memory series per ingester in {{ $labels.namespace }} is too high.
-            |||,
+              The number of in-memory series per ingester in %(alert_aggregation_variables)s is too high.
+            ||| % $._config,
           },
         },
         {
@@ -464,8 +464,8 @@
           },
           annotations: {
             message: |||
-              Ingesters in {{ $labels.namespace }} ingest too many samples per second.
-            |||,
+              Ingesters in %(alert_aggregation_variables)s ingest too many samples per second.
+            ||| % $._config,
           },
         },
         {
@@ -483,8 +483,8 @@
           },
           annotations: {
             message: |||
-              Ingester {{ $labels.namespace }}/{{ $labels.pod }} is using too much memory.
-            |||,
+              Ingester {{ $labels.pod }} in %(alert_aggregation_variables)s is using too much memory.
+            ||| % $._config,
           },
         },
         {
@@ -502,8 +502,8 @@
           },
           annotations: {
             message: |||
-              Ingester {{ $labels.namespace }}/{{ $labels.pod }} is using too much memory.
-            |||,
+              Ingester {{ $labels.pod }} in %(alert_aggregation_variables)s is using too much memory.
+            ||| % $._config,
           },
         },
       ],
@@ -526,8 +526,8 @@
           },
           annotations: {
             message: |||
-              Cortex Ruler {{ $labels.instance }} is experiencing {{ printf "%.2f" $value }}% write (push) errors.
-            |||,
+              Cortex Ruler {{ $labels.instance }} in %(alert_aggregation_variables)s is experiencing {{ printf "%%.2f" $value }}%% write (push) errors.
+            ||| % $._config,
           },
         },
         {
@@ -545,8 +545,8 @@
           },
           annotations: {
             message: |||
-              Cortex Ruler {{ $labels.instance }} is experiencing {{ printf "%.2f" $value }}% errors while evaluating rules.
-            |||,
+              Cortex Ruler {{ $labels.instance }} in %(alert_aggregation_variables)s is experiencing {{ printf "%%.2f" $value }}%% errors while evaluating rules.
+            ||| % $._config,
           },
         },
         {
@@ -563,8 +563,8 @@
           },
           annotations: {
             message: |||
-              Cortex Ruler {{ $labels.instance }} is experiencing {{ printf "%.2f" $value }}% missed iterations for the rule group {{ $labels.rule_group }}.
-            |||,
+              Cortex Ruler {{ $labels.instance }} in %(alert_aggregation_variables)s is experiencing {{ printf "%%.2f" $value }}%% missed iterations for the rule group {{ $labels.rule_group }}.
+            ||| % $._config,
           },
         },
         {
@@ -579,8 +579,8 @@
           },
           annotations: {
             message: |||
-              Cortex Rulers {{ $labels.job }} are experiencing errors when checking the ring for rule group ownership.
-            |||,
+              Cortex Rulers in %(alert_aggregation_variables)s are experiencing errors when checking the ring for rule group ownership.
+            ||| % $._config,
           },
         },
       ],
@@ -600,7 +600,7 @@
             severity: 'warning',
           },
           annotations: {
-            message: '{{ $labels.job }}/{{ $labels.instance }} sees incorrect number of gossip members.',
+            message: 'Cortex instance {{ $labels.instance }} in %(alert_aggregation_variables)s sees incorrect number of gossip members.' % $._config,
           },
         },
       ],
diff --git a/jsonnet/mimir-mixin/alerts/blocks.libsonnet b/jsonnet/mimir-mixin/alerts/blocks.libsonnet
index d1157f38438..a60ac2da263 100644
--- a/jsonnet/mimir-mixin/alerts/blocks.libsonnet
+++ b/jsonnet/mimir-mixin/alerts/blocks.libsonnet
@@ -9,24 +9,24 @@
           alert: 'CortexIngesterHasNotShippedBlocks',
           'for': '15m',
           expr: |||
-            (min by(namespace, instance) (time() - thanos_objstore_bucket_last_successful_upload_time{job=~".+/ingester.*"}) > 60 * 60 * 4)
+            (min by(%(alert_aggregation_labels)s, instance) (time() - thanos_objstore_bucket_last_successful_upload_time{job=~".+/ingester.*"}) > 60 * 60 * 4)
             and
-            (max by(namespace, instance) (thanos_objstore_bucket_last_successful_upload_time{job=~".+/ingester.*"}) > 0)
+            (max by(%(alert_aggregation_labels)s, instance) (thanos_objstore_bucket_last_successful_upload_time{job=~".+/ingester.*"}) > 0)
             and
             # Only if the ingester has ingested samples over the last 4h.
-            (max by(namespace, instance) (rate(cortex_ingester_ingested_samples_total[4h])) > 0)
+            (max by(%(alert_aggregation_labels)s, instance) (rate(cortex_ingester_ingested_samples_total[4h])) > 0)
             and
             # Only if the ingester was ingesting samples 4h ago. This protects from the case the ingester instance
             # had ingested samples in the past, then no traffic was received for a long period and then it starts
             # receiving samples again. Without this check, the alert would fire as soon as it gets back receiving
             # samples, while the a block shipping is expected within the next 4h.
-            (max by(namespace, instance) (rate(cortex_ingester_ingested_samples_total[1h] offset 4h)) > 0)
-          |||,
+            (max by(%(alert_aggregation_labels)s, instance) (rate(cortex_ingester_ingested_samples_total[1h] offset 4h)) > 0)
+          ||| % $._config,
           labels: {
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} has not shipped any block in the last 4 hours.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s has not shipped any block in the last 4 hours.' % $._config,
           },
         },
         {
@@ -35,15 +35,15 @@
           alert: 'CortexIngesterHasNotShippedBlocksSinceStart',
           'for': '4h',
           expr: |||
-            (max by(namespace, instance) (thanos_objstore_bucket_last_successful_upload_time{job=~".+/ingester.*"}) == 0)
+            (max by(%(alert_aggregation_labels)s, instance) (thanos_objstore_bucket_last_successful_upload_time{job=~".+/ingester.*"}) == 0)
             and
-            (max by(namespace, instance) (rate(cortex_ingester_ingested_samples_total[4h])) > 0)
-          |||,
+            (max by(%(alert_aggregation_labels)s, instance) (rate(cortex_ingester_ingested_samples_total[4h])) > 0)
+          ||| % $._config,
           labels: {
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} has not shipped any block in the last 4 hours.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s has not shipped any block in the last 4 hours.' % $._config,
           },
         },
         {
@@ -61,7 +61,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: "Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} has compacted a block {{ $value | humanizeDuration }} ago but it hasn't been successfully uploaded to the storage yet.",
+            message: "Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s has compacted a block {{ $value | humanizeDuration }} ago but it hasn't been successfully uploaded to the storage yet." % $._config,
           },
         },
         {
@@ -77,7 +77,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} is failing to compact TSDB head.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s is failing to compact TSDB head.' % $._config,
           },
         },
         {
@@ -89,7 +89,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} is failing to truncate TSDB head.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s is failing to truncate TSDB head.' % $._config,
           },
         },
         {
@@ -101,7 +101,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} is failing to create TSDB checkpoint.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s is failing to create TSDB checkpoint.' % $._config,
           },
         },
         {
@@ -113,7 +113,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} is failing to delete TSDB checkpoint.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s is failing to delete TSDB checkpoint.' % $._config,
           },
         },
         {
@@ -125,7 +125,7 @@
             severity: 'warning',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} is failing to truncate TSDB WAL.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s is failing to truncate TSDB WAL.' % $._config,
           },
         },
         {
@@ -137,7 +137,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} got a corrupted TSDB WAL.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s got a corrupted TSDB WAL.' % $._config,
           },
         },
         {
@@ -150,7 +150,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Ingester {{ $labels.namespace }}/{{ $labels.instance }} is failing to write to TSDB WAL.',
+            message: 'Cortex Ingester {{ $labels.instance }} in %(alert_aggregation_variables)s is failing to write to TSDB WAL.' % $._config,
           },
         },
         {
@@ -166,7 +166,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Querier {{ $labels.namespace }}/{{ $labels.instance }} has not successfully scanned the bucket since {{ $value | humanizeDuration }}.',
+            message: 'Cortex Querier {{ $labels.instance }} in %(alert_aggregation_variables)s has not successfully scanned the bucket since {{ $value | humanizeDuration }}.' % $._config,
           },
         },
         {
@@ -177,20 +177,20 @@
           expr: |||
             100 * (
               (
-                sum by(namespace) (rate(cortex_querier_storegateway_refetches_per_query_count[5m]))
+                sum by(%(alert_aggregation_labels)s) (rate(cortex_querier_storegateway_refetches_per_query_count[5m]))
                 -
-                sum by(namespace) (rate(cortex_querier_storegateway_refetches_per_query_bucket{le="0.0"}[5m]))
+                sum by(%(alert_aggregation_labels)s) (rate(cortex_querier_storegateway_refetches_per_query_bucket{le="0.0"}[5m]))
               )
               /
-              sum by(namespace) (rate(cortex_querier_storegateway_refetches_per_query_count[5m]))
+              sum by(%(alert_aggregation_labels)s) (rate(cortex_querier_storegateway_refetches_per_query_count[5m]))
             )
             > 1
-          |||,
+          ||| % $._config,
           labels: {
             severity: 'warning',
           },
           annotations: {
-            message: 'Cortex Queries in {{ $labels.namespace }} are refetching series from different store-gateways (because of missing blocks) for the {{ printf "%.0f" $value }}% of queries.',
+            message: 'Cortex Queries in %(alert_aggregation_variables)s are refetching series from different store-gateways (because of missing blocks) for the {{ printf "%%.0f" $value }}%% of queries.' % $._config,
           },
         },
         {
@@ -206,20 +206,20 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Store Gateway {{ $labels.namespace }}/{{ $labels.instance }} has not successfully synched the bucket since {{ $value | humanizeDuration }}.',
+            message: 'Cortex Store Gateway {{ $labels.instance }} in %(alert_aggregation_variables)s has not successfully synched the bucket since {{ $value | humanizeDuration }}.' % $._config,
           },
         },
         {
           // Alert if the bucket index has not been updated for a given user.
           alert: 'CortexBucketIndexNotUpdated',
           expr: |||
-            min by(namespace, user) (time() - cortex_bucket_index_last_successful_update_timestamp_seconds) > 7200
-          |||,
+            min by(%(alert_aggregation_labels)s, user) (time() - cortex_bucket_index_last_successful_update_timestamp_seconds) > 7200
+          ||| % $._config,
           labels: {
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex bucket index for tenant {{ $labels.user }} in {{ $labels.namespace }} has not been updated since {{ $value | humanizeDuration }}.',
+            message: 'Cortex bucket index for tenant {{ $labels.user }} in %(alert_aggregation_variables)s has not been updated since {{ $value | humanizeDuration }}.' % $._config,
           },
         },
         {
@@ -227,13 +227,13 @@
           alert: 'CortexTenantHasPartialBlocks',
           'for': '6h',
           expr: |||
-            max by(namespace, user) (cortex_bucket_blocks_partials_count) > 0
-          |||,
+            max by(%(alert_aggregation_labels)s, user) (cortex_bucket_blocks_partials_count) > 0
+          ||| % $._config,
           labels: {
             severity: 'warning',
           },
           annotations: {
-            message: 'Cortex tenant {{ $labels.user }} in {{ $labels.namespace }} has {{ $value }} partial blocks.',
+            message: 'Cortex tenant {{ $labels.user }} in %(alert_aggregation_variables)s has {{ $value }} partial blocks.' % $._config,
           },
         },
       ],
diff --git a/jsonnet/mimir-mixin/alerts/compactor.libsonnet b/jsonnet/mimir-mixin/alerts/compactor.libsonnet
index 1f28a7e54a1..5538545e249 100644
--- a/jsonnet/mimir-mixin/alerts/compactor.libsonnet
+++ b/jsonnet/mimir-mixin/alerts/compactor.libsonnet
@@ -14,7 +14,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Compactor {{ $labels.namespace }}/{{ $labels.instance }} has not successfully cleaned up blocks in the last 6 hours.',
+            message: 'Cortex Compactor {{ $labels.instance }} in %(alert_aggregation_variables)s has not successfully cleaned up blocks in the last 6 hours.' % $._config,
           },
         },
         {
@@ -30,7 +30,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Compactor {{ $labels.namespace }}/{{ $labels.instance }} has not run compaction in the last 24 hours.',
+            message: 'Cortex Compactor {{ $labels.instance }} in %(alert_aggregation_variables)s has not run compaction in the last 24 hours.' % $._config,
           },
         },
         {
@@ -44,7 +44,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Compactor {{ $labels.namespace }}/{{ $labels.instance }} has not run compaction in the last 24 hours.',
+            message: 'Cortex Compactor {{ $labels.instance }} in %(alert_aggregation_variables)s has not run compaction in the last 24 hours.' % $._config,
           },
         },
         {
@@ -57,7 +57,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Compactor {{ $labels.namespace }}/{{ $labels.instance }} failed to run 2 consecutive compactions.',
+            message: 'Cortex Compactor {{ $labels.instance }} in %(alert_aggregation_variables)s failed to run 2 consecutive compactions.' % $._config,
           },
         },
         {
@@ -73,7 +73,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Compactor {{ $labels.namespace }}/{{ $labels.instance }} has not uploaded any block in the last 24 hours.',
+            message: 'Cortex Compactor {{ $labels.instance }} in %(alert_aggregation_variables)s has not uploaded any block in the last 24 hours.' % $._config,
           },
         },
         {
@@ -87,7 +87,7 @@
             severity: 'critical',
           },
           annotations: {
-            message: 'Cortex Compactor {{ $labels.namespace }}/{{ $labels.instance }} has not uploaded any block in the last 24 hours.',
+            message: 'Cortex Compactor {{ $labels.instance }} in %(alert_aggregation_variables)s has not uploaded any block in the last 24 hours.' % $._config,
           },
         },
       ],
diff --git a/jsonnet/mimir-mixin/groups.libsonnet b/jsonnet/mimir-mixin/groups.libsonnet
index 6d33ea3661d..c2c35f90d21 100644
--- a/jsonnet/mimir-mixin/groups.libsonnet
+++ b/jsonnet/mimir-mixin/groups.libsonnet
@@ -41,5 +41,22 @@
         alert_aggregation_labels_override
       )
       else group_by_cluster,
+
+    // This field contains contains the Prometheus template variables that should
+    // be used to display values of the configured "group_by_cluster" (or the
+    // deprecated "alert_aggregation_labels").
+    alert_aggregation_variables:
+      std.join(
+        '/',
+        // Generate the variable replacement for each label.
+        std.map(
+          function(l) '{{ $labels.%s }}' % l,
+          // Split the configured labels by comma and remove whitespaces.
+          std.map(
+            function(l) std.strReplace(l, ' ', ''),
+            std.split($._config.alert_aggregation_labels, ',')
+          ),
+        ),
+      ),
   },
 }